Cellular Adaptation and Injury
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Questions and Answers

What is metaplasia?

  • Reversible replacement of one mature cell type with another (correct)
  • Uncontrolled growth of cells leading to tumors
  • A process related to nutritional imbalances
  • Permanent replacement of one cell type with another

Which of the following best describes dysplasia?

  • A process strictly involving genetic mutations
  • An adaptive response to injury
  • A reversible process that leads to normal cell growth
  • Irregular growth of cells with varying size and shape (correct)

What causes free radical injury?

  • Excessive nutrient intake
  • Physical trauma to tissues
  • Oxidative stress from uncharged atoms with unpaired electrons (correct)
  • Malfunction of the immune system

Which of the following is a type of physical agent that can cause cellular injury?

<p>Extreme temperatures (A)</p> Signup and view all the answers

How can radiation injury affect cells?

<p>Through damaging DNA and producing free radicals (A)</p> Signup and view all the answers

What is a common outcome of persistent severe irritation of a tissue?

<p>Neoplasms and cancer development (D)</p> Signup and view all the answers

Which of the following agents can cause chemical injury to cells?

<p>Carbon monoxide (A)</p> Signup and view all the answers

What is most closely associated with impaired calcium homeostasis?

<p>Cellular injury and death (C)</p> Signup and view all the answers

What is the primary feature of atrophy in cellular change?

<p>Shrinkage in cell size (B)</p> Signup and view all the answers

Which condition is an example of physiologic hypertrophy?

<p>Enlargement of the uterus during pregnancy (B)</p> Signup and view all the answers

Which of the following correctly describes hyperplasia?

<p>Increase in the number of cells through division (C)</p> Signup and view all the answers

What distinguishes pathologic adaptation from physiologic adaptation?

<p>Pathologic adaptation occurs in response to damaging stimuli. (C)</p> Signup and view all the answers

What type of cellular adaptation involves an increase in the size of the organ?

<p>Hypertrophy (C)</p> Signup and view all the answers

Which of the following is a possible cause of atrophy?

<p>Inadequate nutrition (B)</p> Signup and view all the answers

Which of the following cellular adaptations is often reversible?

<p>Metaplasia (C)</p> Signup and view all the answers

Which mechanism is associated with compensatory hyperplasia?

<p>Removal of significant tissue (C)</p> Signup and view all the answers

What is the most common cause of cell injury?

<p>Ischemia (B)</p> Signup and view all the answers

Which of the following can lead to hypoxic cell injury?

<p>Increased altitude (D)</p> Signup and view all the answers

Which cellular response is NOT associated with hypoxia?

<p>Increased ATP production (C)</p> Signup and view all the answers

What is ischemia-reperfusion injury primarily caused by?

<p>Oxidative stress (D)</p> Signup and view all the answers

Which of the following is a result of impaired calcium homeostasis?

<p>Increased cytosolic calcium levels (C)</p> Signup and view all the answers

Which condition can lead to asphyxial injuries?

<p>Obstructed airway (A)</p> Signup and view all the answers

What common injury can arise from oxidative stress?

<p>Stroke (D)</p> Signup and view all the answers

Which of the following factors does NOT contribute to oxidative stress?

<p>High levels of ATP (A)</p> Signup and view all the answers

What role does calcium play in cellular function?

<p>It acts as a second messenger that can activate intracellular enzymes. (B)</p> Signup and view all the answers

Which condition is an example of abnormal endogenous products accumulation in cells?

<p>Tay-Sachs disease (B)</p> Signup and view all the answers

What is dystrophic calcification commonly associated with?

<p>Deposition of calcium salts in injured tissue. (A)</p> Signup and view all the answers

What characterizes necrosis compared to apoptosis?

<p>Necrosis results in inflammation and interferes with tissue regeneration. (B)</p> Signup and view all the answers

Which lab value signifies possible cell injury by indicating an increase in white blood cells?

<p>Leukocytosis (B)</p> Signup and view all the answers

What is the main difference between reversible cell injury and irreversible cell injury?

<p>Reversible injury allows for complete recovery, while irreversible leads to cell death. (A)</p> Signup and view all the answers

What is a common cause of metastatic calcification?

<p>Hypercalcemia due to various conditions. (B)</p> Signup and view all the answers

Which of the following is true regarding pathological calcifications?

<p>Dystrophic calcification is related to tissue injury, while metastatic calcification to calcium imbalance. (A)</p> Signup and view all the answers

What is the primary cause of dry gangrene?

<p>Lack of blood supply (D)</p> Signup and view all the answers

What results from the invasion of neutrophils in wet gangrene?

<p>Liquefactive necrosis (D)</p> Signup and view all the answers

What is the significance of telomeres in cellular aging?

<p>They become too short, halting cell division (C)</p> Signup and view all the answers

Which factor is NOT directly linked to cellular aging?

<p>Sarcomere development (A)</p> Signup and view all the answers

In gas gangrene, what causes the bubbles of gas observed in the infected area?

<p>Hydrolytic toxins from Clostridium (B)</p> Signup and view all the answers

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