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Questions and Answers

What is a primary function of epithelial cells?

  • Connect and support body structures
  • Provide voluntary muscle movement
  • Transport blood through the body
  • Secrete and absorb ions and organic molecules (correct)

Which type of connective tissue forms ligaments?

  • Adipose tissue
  • Loose connective tissue
  • Fibrous connective tissue (correct)
  • Blood

What characteristic distinguishes skeletal muscle cells?

  • Presence in the heart
  • Involuntary movement
  • Found in blood vessels
  • Anchored by tendons to bone (correct)

Which connective tissue disease primarily features abnormal immune activity with inflammation?

<p>Rheumatoid Arthritis (D)</p> Signup and view all the answers

Where are simple columnar epithelial cells primarily found?

<p>In the stomach and intestines (D)</p> Signup and view all the answers

What is a characteristic feature of cardiac muscle cells?

<p>Involuntary control (A)</p> Signup and view all the answers

Which type of epithelial cells replicate often to replace damaged or dead cells?

<p>Stratified squamous (B)</p> Signup and view all the answers

What is the primary function of connective tissue?

<p>Support and anchor body structures (A)</p> Signup and view all the answers

What is the primary factor that affects extracellular fluid (ECF) volume in the body?

<p>Amount of sodium in the body (C)</p> Signup and view all the answers

Which of the following diseases is primarily associated with neural cells?

<p>Lou Gehrig’s Disease (A), Myasthenia Gravis (C)</p> Signup and view all the answers

Osmosis is defined as the movement of which substance across a semi-permeable membrane?

<p>Water (D)</p> Signup and view all the answers

Which term describes the ability of an extracellular solution to influence water movement into or out of a cell?

<p>Tonicity (A)</p> Signup and view all the answers

What is the main function of the cell membrane?

<p>Act as a barrier that controls molecule movement (D)</p> Signup and view all the answers

What does an increase in sodium ion concentration in extracellular fluid typically cause?

<p>Increase in osmolarity of the blood (D)</p> Signup and view all the answers

What is the term for the process by which ions entering a cell can trigger a potential change?

<p>Graded potentials (D)</p> Signup and view all the answers

Which communication method involves a signal being sent to the same cell?

<p>Autocrine (D)</p> Signup and view all the answers

What characterizes penetrating solutes?

<p>They readily move across the cell membrane (C)</p> Signup and view all the answers

What determines the water balance in the extracellular fluid?

<p>Sodium plasma levels (C)</p> Signup and view all the answers

What is a primary characteristic of connective tissue cells?

<p>They connect, anchor, and support body structures. (A)</p> Signup and view all the answers

Which type of muscle tissue is responsible for involuntary movements?

<p>Cardiac muscle. (B), Smooth muscle. (C)</p> Signup and view all the answers

Which of the following diseases primarily impacts connective tissue?

<p>Rheumatoid Arthritis. (A)</p> Signup and view all the answers

What type of epithelial cells are involved in secretion and absorption?

<p>Simple cuboidal. (C)</p> Signup and view all the answers

Which connective tissue component is responsible for elasticity?

<p>Elastin. (A)</p> Signup and view all the answers

The primary function of epithelial cells lining the stomach and intestines is to:

<p>Facilitate absorption and secretion. (C)</p> Signup and view all the answers

Which type of connective tissue is found under the skin?

<p>Loose connective tissue. (A), Adipose tissue. (D)</p> Signup and view all the answers

Which type of muscle allows for locomotion and maintaining posture?

<p>Skeletal muscle. (D)</p> Signup and view all the answers

What is true about stratified squamous epithelial cells?

<p>They are primarily found in areas subject to abrasion. (D)</p> Signup and view all the answers

Which disease is characterized by abnormal immune activity and inflammation affecting connective tissue?

<p>Lupus. (C)</p> Signup and view all the answers

What role does the phospholipid bilayer of the cell membrane play in the body?

<p>Serves as a barrier that slows diffusion of molecules (B)</p> Signup and view all the answers

Which of the following is true regarding intracellular fluid and sodium levels?

<p>Intracellular fluid contains higher levels of potassium (A)</p> Signup and view all the answers

In which phase of the cell cycle does DNA replication occur?

<p>S Phase (D)</p> Signup and view all the answers

What is the effect of hyperpolarization on a neuron's action potential?

<p>It decreases the likelihood of generating an action potential (D)</p> Signup and view all the answers

What distinguishes an active transport process from passive transport?

<p>Active transport requires energy input while passive does not (C)</p> Signup and view all the answers

Which statement best describes the role of tumor suppressor protein P53?

<p>Regulates cell cycle checkpoints to prevent cancer (D)</p> Signup and view all the answers

What can result from excessive sodium intake in terms of extracellular fluid volume?

<p>It increases extracellular fluid volume due to sodium retention (B)</p> Signup and view all the answers

Which type of receptor regulation involves decreasing the number of active receptors on the cell surface?

<p>Downregulation (D)</p> Signup and view all the answers

Which type of cell communication sends signals to neighboring cells?

<p>Paracrine (B)</p> Signup and view all the answers

What is the main purpose of cell differentiation?

<p>To allow cells to perform specialized functions (A)</p> Signup and view all the answers

What occurs when a mutation affects the regulatory checkpoints in the cell cycle?

<p>The checkpoints cease functioning. (B)</p> Signup and view all the answers

Which type of stem cell can differentiate into any cell type but cannot form placental tissue?

<p>Pluripotent stem cells (C)</p> Signup and view all the answers

Which cells are categorized as permanent cells?

<p>Brain cells (C)</p> Signup and view all the answers

What is hypertrophy primarily characterized by?

<p>Increase in cell size and functioning mass (D)</p> Signup and view all the answers

What type of adaptation occurs in tissues capable of mitotic division?

<p>Hyperplasia (C)</p> Signup and view all the answers

Which condition is an example of dysplasia?

<p>Cervical cancer (C)</p> Signup and view all the answers

What happens to stable cells when growth ceases?

<p>They enter G0 and may re-enter the cycle later. (A)</p> Signup and view all the answers

Which type of adaptation involves cell conversion to a different cell type?

<p>Metaplasia (D)</p> Signup and view all the answers

What is a common result of pathological hyperplasia?

<p>Increased risk of cancer development (C)</p> Signup and view all the answers

Which of the following statements about quiescent cells is accurate?

<p>They stop dividing under normal conditions. (C)</p> Signup and view all the answers

Which of the following functions are primarily associated with epithelial cells?

<p>Secretion, absorption, and sensory information (B)</p> Signup and view all the answers

What is a key characteristic of connective tissue?

<p>It is the most abundant tissue in the body (A)</p> Signup and view all the answers

Which type of muscle is voluntary and primarily responsible for locomotion?

<p>Skeletal muscle (C)</p> Signup and view all the answers

Which connective tissue disease is characterized mainly by abnormal immune activity and inflammation?

<p>Ehlers-Danlos Syndrome (B)</p> Signup and view all the answers

Which type of connective tissue is specialized for energy storage?

<p>Adipose tissue (B)</p> Signup and view all the answers

What is primarily responsible for the stretchability of connective tissue?

<p>Elastin (D)</p> Signup and view all the answers

Which type of epithelial cells is oriented to facilitate absorption in the digestive system?

<p>Simple columnar (A)</p> Signup and view all the answers

Which is a role of muscle cells aside from movement?

<p>Maintaining metabolic functions (C)</p> Signup and view all the answers

What distinguishes cardiac muscle from skeletal muscle?

<p>Cardiac muscle is involuntary and found only in the heart (A)</p> Signup and view all the answers

Which epithelial tissue type provides the most effective barrier against abrasions?

<p>Stratified squamous (D)</p> Signup and view all the answers

What is the main consequence of a mutation affecting regulatory checkpoints during the cell cycle?

<p>Further mutations may occur (A)</p> Signup and view all the answers

Which type of stem cells has the ability to differentiate into any cell type except for placental cells?

<p>Pluripotent stem cells (D)</p> Signup and view all the answers

What characterizes quiescent cells?

<p>They enter G0 and remain inactive (A)</p> Signup and view all the answers

Which adaptation is primarily defined as an increase in the number of cells in a tissue capable of mitotic division?

<p>Hyperplasia (B)</p> Signup and view all the answers

Which of the following is an example of physiological hyperplasia?

<p>Increased breast tissue during pregnancy (C)</p> Signup and view all the answers

What primarily happens to mature stem cells in the process of differentiation?

<p>They choose a specific cell fate (D)</p> Signup and view all the answers

What defines the process of atrophy in cells?

<p>Decrease in cell size (D)</p> Signup and view all the answers

Which condition is characterized by deranged cell growth that can lead to cancer?

<p>Dysplasia (B)</p> Signup and view all the answers

Which type of cell is classified as a permanent cell and cannot regenerate?

<p>Brain cells (B)</p> Signup and view all the answers

What characterizes hypertrophy in tissues?

<p>Increase in cell size and mass (C)</p> Signup and view all the answers

Which disease is primarily associated with voluntary muscle dysfunction?

<p>Myasthenia Gravis (B)</p> Signup and view all the answers

How does an increase in the concentration of NaCl in the extracellular environment primarily affect fluid compartments?

<p>It increases total extracellular fluid volume. (A)</p> Signup and view all the answers

What ion movement is associated with depolarization of a neuron?

<p>Movement of Na+ into the cell (C)</p> Signup and view all the answers

What is the main role of P53 in the cell cycle?

<p>To act as a tumor suppressor (C)</p> Signup and view all the answers

What is the key difference between penetrating and nonpenetrating solutes?

<p>Nonpenetrating solutes cannot readily move across the cell membrane. (A)</p> Signup and view all the answers

What type of cell communication involves sending signals to another nearby cell?

<p>Paracrine (D)</p> Signup and view all the answers

Which checkpoint in the cell cycle assesses DNA damage before mitosis?

<p>G2 Checkpoint (A)</p> Signup and view all the answers

What commonly results from excessive proliferation in cells due to checkpoint mutations?

<p>Tumor growth (C)</p> Signup and view all the answers

Which of the following terms refers to the total concentration of all solutes in a solution?

<p>Osmolarity (D)</p> Signup and view all the answers

What is the primary function of autocrine signaling in cellular communication?

<p>To allow a cell to respond to its own signals (A)</p> Signup and view all the answers

Flashcards

Epithelial cells function

Cover and line body surfaces; specialized for secretion, absorption, and providing sensory information. They also aid in transport and replicate often.

Connective tissue function

Connects, anchors, and supports body structures. It's the most abundant tissue type, providing structural framework.

Skeletal muscle function

Anchored to bone by tendons, responsible for movement (locomotion and posture). Voluntary.

Cardiac muscle location

Found only in the heart; responsible for heart contractions. Involuntary.

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Smooth muscle location

Found in organs like esophagus, stomach, intestines, bladder, and blood vessels. Involuntary.

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Simple squamous cells

Thin, flat cells, often forming linings for diffusion.

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Connective tissue proper type

Includes loose connective tissue (under skin), adipose tissue, and fibrous connective tissue (ligaments).

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Specialized connective tissue types

Includes blood, cartilage, and bone.

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Fluid compartments

Body compartments separated by selectively permeable membranes, controlling water and solute movement.

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Intracellular fluid (ICF)

Fluid inside cells, high in potassium, low in sodium.

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Extracellular fluid (ECF)

Fluid outside cells, high in sodium, low in potassium.

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Osmolarity

Total concentration of solutes in a solution.

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Tonicity

Ability of a solution to cause water movement into or out of a cell.

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Diffusion

Movement of molecules from high to low concentration.

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Action Potential

All-or-none electrical signal in a neuron.

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Depolarization

Cell becomes less negative, bringing action potential closer.

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Hyperpolarization

Cell becomes more negative, moving farther from action potential.

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Sodium (Na+) balance

Amount of sodium in the body influences extracellular fluid volume.

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Epithelial cells: Role

Epithelial cells cover and line body surfaces, serving as a protective barrier. They also specialize in secretion, absorption, and sensory information. They replicate frequently to repair damage.

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Epithelial cell types

Epithelial cells come in various forms, including simple squamous, simple cuboidal, simple columnar, stratified squamous, stratified cuboidal, and stratified columnar. Each type is adapted for specific functions based on its location in the body.

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Connective Tissue: Components

Connective tissue is primarily composed of collagen and elastin, which are essential for its structural strength and elasticity.

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Connective Tissue Proper

Connective tissue proper includes loose connective tissue (found under the skin), adipose tissue (for fat storage), and fibrous connective tissue (forming ligaments).

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Specialized Connective Tissue

Specialized connective tissue includes blood (containing red and white blood cells), cartilage (found at the ends of bones), and bone (for support and protection).

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Connective Tissue Diseases

Connective tissue diseases target the connective tissue framework. These diseases are often characterized by inflammation caused by abnormal immune activity.

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Skeletal Muscle: Role

Skeletal muscle, attached to bones by tendons, is responsible for voluntary movement, such as locomotion and maintaining posture.

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Cardiac Muscle: Characteristics

Found only in the heart, cardiac muscle is responsible for involuntary heart contractions. It is specialized for rhythmic contractions.

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Smooth Muscle: Function

Smooth muscle, found in various organs like the esophagus, stomach, bladder, and blood vessels, controls involuntary movements like peristalsis and blood vessel constriction.

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What is a Neuron?

A specialized cell that makes up the nervous system, responsible for initiating, integrating, and conducting electrical signals to other cells.

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What are 'Graded Potentials'?

Changes in membrane potential that can either depolarize (bring the cell closer to firing) or hyperpolarize (move it farther away from firing) the cell.

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What are 'Action Potentials'?

All-or-none electrical signals in neurons that propagate down the axon, transmitting information.

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What is 'Depolarization'?

A change in the cell membrane potential that makes the inside of the cell less negative (more positive), bringing it closer to firing an action potential.

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What is 'Hyperpolarization'?

A change in the cell membrane potential that makes the inside of the cell more negative, moving it farther away from firing an action potential.

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What is 'Tonicity'?

The ability of an extracellular solution to make water move into or out of a cell by osmosis. It's determined by the concentration of non-penetrating solutes.

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What is 'Osmolarity'?

The total concentration of all solutes in a solution, expressed as osmoles of solute per liter of solution.

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What is 'Cell Communication'?

The way cells interact with each other through chemical signals. This can be autocrine, paracrine, endocrine, or neuroendocrine.

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What is 'Differentiation'?

The process by which cells become more specialized in structure and function, depending on the stimuli they interact with.

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What is 'Proliferation'?

The increase in the number of cells through mitotic divisions, often stimulated by growth factors, hormones, and cytokines.

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What happens when a checkpoint mutation occurs?

A mutation in a cell cycle checkpoint disables it, allowing uncontrolled cell division and increasing the chance of further mutations.

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What are the 3 main stimulators of cell proliferation?

Growth factors, hormones (like estrogen/testosterone), and cytokines all promote cell division.

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Totipotent stem cell

Totipotent stem cells can develop into any cell type, including the placenta and embryo.

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Pluripotent stem cell

Pluripotent stem cells can become any of the three germ layers (ectoderm, mesoderm, endoderm), but not placental tissue.

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Multipotent stem cell

Multipotent stem cells are limited to a specific cell lineage, like skin, muscle, or neural tissue.

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Liable cells

Liable cells are constantly dividing and never enter G0 (resting phase). Found in tissues like the stomach and skin.

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Stable cells

Stable cells enter G0 but can re-enter the cell cycle for repair or regeneration. Found in tissues like the liver.

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Quiescent cells

Quiescent cells are normally in a non-dividing state, only dividing under specific conditions.

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Permanent cells

Permanent cells exit the cell cycle and cannot divide again.

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Hypertrophy

Hypertrophy is an increase in cell size, leading to larger tissue mass. Occurs in tissues that can't divide.

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What is a neuron's role?

Neurons are specialized cells responsible for initiating, integrating, and conducting electrical signals to other cells.

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What is an action potential?

An action potential is a brief electrical pulse that travels down the axon of a neuron, transmitting information.

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Checkpoint Mutation

A genetic change in a cell's control system that disrupts the normal checkpoints of the cell cycle. This disrupts the regulation of cell division and increases the risk of further mutations.

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Cell Proliferation Stimulators

Substances that trigger cell division, including growth factors, hormones (like estrogen or testosterone), and cytokines.

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Hyperplasia

An increase in the number of cells in a tissue or organ. This occurs in tissues that can divide.

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Atrophy

A decrease in cell size due to reduced demands or adverse conditions.

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Epithelial cells

Cells that cover and line body surfaces, specialized for secretion, absorption, and sensory information. They replicate often to replace damaged cells and are avascular (lack blood vessels).

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What are the functions of epithelial cells?

Epithelial cells cover and line body surfaces, secrete substances, absorb nutrients, provide sensory information, and aid in transporting filtered material through active transport.

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Connective tissue

Tissue that connects, anchors, and supports body structures. It is the most abundant tissue in the body and contains collagen and elastin for strength and flexibility.

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What are the main types of connective tissue?

Connective tissue proper includes loose connective tissue, adipose tissue, and fibrous connective tissue. Specialized connective tissue includes blood, cartilage, and bone.

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Skeletal muscle

Muscle anchored to bone by tendons, providing voluntary movement like locomotion and posture.

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Cardiac muscle

Muscle found only in the heart, responsible for involuntary heart contractions.

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Smooth muscle

Muscle found in various organs, controlling involuntary movements like digestion and regulating blood flow.

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What are the 3 types of muscle cells?

The three types of muscle cells are skeletal muscle (voluntary movement), cardiac muscle (involuntary heart contractions), and smooth muscle (involuntary movements in organs).

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What are the 2 main structural proteins in connective tissues?

The two main structural proteins in connective tissues are collagen and elastin. Collagen provides strength and structure, while elastin gives connective tissues flexibility and resilience.

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Study Notes

Cell Types and Functions

  • Epithelial Cells: Cover and line body surfaces, specializing in secretion and absorption. They replicate frequently to replace damaged cells and provide sensory input. They are avascular and aid in transporting filtered material. Example cell types include simple squamous, simple cuboidal, simple columnar, stratified squamous, stratified cuboidal, and stratified columnar. Examples include skin cells, cells lining the stomach and intestines. Diseases affecting epithelial cells include eczema, psoriasis, dermatitis, and carcinoma.

Connective Tissue Cells

  • Connective Tissue: The most abundant tissue, connecting, anchoring, and supporting body structures. It forms a framework, and contains collagen and elastin as major structural proteins. Diseases targeting connective tissue include abnormal immune activity, inflammation, rheumatoid arthritis, lupus, Marfan syndrome, Ehlers-Danlos syndrome, and scleroderma. Examples of connective tissue include loose connective tissue (under the skin), adipose tissue, fibrous connective tissue (ligaments), blood (WBCs, RBCs, plasma), cartilage, and bone.

Muscle Cells

  • Muscle Cells: Three types:
    • Skeletal Muscle: Anchored to bone, providing voluntary movement and posture.
    • Cardiac Muscle: Found only in the heart, involuntary.
    • Smooth Muscle: Found in organs like the esophagus, stomach, intestines, bladder, and blood vessels, involuntary. Diseases affecting muscle cells include Lou Gehrig's disease, atrophy, muscular dystrophy, myasthenia gravis, and cardiomyopathy.

Neural Cells

  • Neural Cells: Compose the nervous system, specialized for initiating, integrating, and conducting electrical signals. Diseases affecting neural cells include multiple sclerosis, Parkinson's disease, Alzheimer's disease, stroke, shingles, depression, and anxiety.

Cell Membrane Functions and Ion Movement

  • Cell Membrane: A phospholipid bilayer, forming the external barrier of cells. Functions include establishing fluid compartments, detecting chemical signals, linking cells, and acting as a diffusion barrier. Movement across the membrane includes diffusion from high to low concentration.

Fluid Compartments and Na+/Water Relationship

  • Fluid Compartments: Separated by selectively permeable membranes. Total body water is approximately 42 liters (60% of body weight).
    • Intracellular fluid (28L or 2/3 TBW): Higher K+, lower Na+
    • Extracellular fluid (14L or 1/3 TBW): Higher Na+, lower K+. Components include interstitial fluid and plasma.
  • The concentration of sodium in the body is a key determinant of ECF volume. Increased dietary salt increases ECF; decreased dietary water decreases ECF concentration.

Movement of Water and Molecules

  • Diffusion: Movement of substances from high to low concentration.
  • Osmosis: Movement of water across a selectively permeable membrane.
  • Osmolarity: Total concentration of solutes in a solution (osmoles per liter of solution).
    • Penetrating solutes: can cross cell membranes readily (e.g., urea)
    • Non-penetrating solutes: cannot cross easily (e.g., Na+, Cl-)
  • Tonicity: Effect of an extracellular solution on water movement into or out of a cell.

Action Potentials and Ion Movement

  • Action Potentials: Generated by ion movement leading to depolarization or hyperpolarization of the cell.
    • Depolarization (EPSP): Increased likelihood of an action potential
    • Hyperpolarization (IPSP): Decreases likelihood of an action potential.
  • Graded Potentials: Changes in membrane potential that vary in size depending on stimulus strength.

Cell Communication and Receptor Regulation

  • Cell Communication: Cells communicate through different mechanisms (autocrine, paracrine, endocrine, neuroendocrine). -Cells regulate responses by changing the number of active receptors.

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Test your knowledge on the various types of cells, including epithelial and connective tissue cells. Explore their functions, examples, and diseases associated with each type. This quiz will help reinforce your understanding of cellular structures and their roles in the body.

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