Podcast
Questions and Answers
How does the structure of a cell membrane contribute to its function as a selective barrier?
How does the structure of a cell membrane contribute to its function as a selective barrier?
The phospholipid bilayer with embedded proteins allows selective passage of molecules. Hydrophobic core repels polar molecules, while protein channels facilitate transport.
How do prokaryotic cells ensure resistance to antibiotics in challenging environments?
How do prokaryotic cells ensure resistance to antibiotics in challenging environments?
Plasmid DNA confers unique phenotypic characters, including resistance to antibiotics, enhancing survival in hostile conditions.
Explain why cells are considered the basic units of life and how this relates to the complexity of living organisms.
Explain why cells are considered the basic units of life and how this relates to the complexity of living organisms.
Cells are the fundamental structural and functional units because they can independently perform essential life functions, highlighting organizational hierarchy.
Describe the roles of rough endoplasmic reticulum and smooth endoplasmic reticulum in protein production and lipid metabolism, respectively?
Describe the roles of rough endoplasmic reticulum and smooth endoplasmic reticulum in protein production and lipid metabolism, respectively?
What implications does the presence of a single circular DNA molecule in mitochondria have for mitochondrial inheritance and disease?
What implications does the presence of a single circular DNA molecule in mitochondria have for mitochondrial inheritance and disease?
Outline the key differences between mitosis and meiosis concerning chromosome number and genetic variation?
Outline the key differences between mitosis and meiosis concerning chromosome number and genetic variation?
Describe the key features and implications of mitochondrial replacement therapy techniques.
Describe the key features and implications of mitochondrial replacement therapy techniques.
What is the significance of the fluid mosaic model in describing the structure of the cell membrane?
What is the significance of the fluid mosaic model in describing the structure of the cell membrane?
How does the absence of a nuclear membrane in prokaryotic cells affect genetic material accessibility?
How does the absence of a nuclear membrane in prokaryotic cells affect genetic material accessibility?
In what ways do plant cells utilize their cell walls to interact with their environment?
In what ways do plant cells utilize their cell walls to interact with their environment?
How does the structural organization of a chloroplast contribute to the process of photosynthesis?
How does the structural organization of a chloroplast contribute to the process of photosynthesis?
What evolutionary advantages do eukaryotes gain through compartmentalization via membrane-bound organelles?
What evolutionary advantages do eukaryotes gain through compartmentalization via membrane-bound organelles?
Examine the role of the Golgi apparatus in modifying and trafficking proteins, considering its significance in cellular functions.
Examine the role of the Golgi apparatus in modifying and trafficking proteins, considering its significance in cellular functions.
Assess how mutations in mitochondrial DNA (mtDNA) may lead to various human diseases, considering maternal inheritance patterns.
Assess how mutations in mitochondrial DNA (mtDNA) may lead to various human diseases, considering maternal inheritance patterns.
Compare and contrast the significance of mitosis versus meiosis in ensuring genetic continuity and variation in organisms.
Compare and contrast the significance of mitosis versus meiosis in ensuring genetic continuity and variation in organisms.
Describe how the unique structure of sperm cells enhances their function in fertilization.
Describe how the unique structure of sperm cells enhances their function in fertilization.
Analyze the challenges associated with mitochondrial replacement therapy considering ethical concerns and technical complexities.
Analyze the challenges associated with mitochondrial replacement therapy considering ethical concerns and technical complexities.
Explain the functions of the centrosome and centrioles, and their importance specifically in animal cells.
Explain the functions of the centrosome and centrioles, and their importance specifically in animal cells.
In the context of DNA barcoding consider whether it is a reliable method of distinguishing species that are closely related, but morphologically similar?
In the context of DNA barcoding consider whether it is a reliable method of distinguishing species that are closely related, but morphologically similar?
Illustrate how errors during DNA replication can lead to mutations and their subsequent effects on cellular function and organismal health.
Illustrate how errors during DNA replication can lead to mutations and their subsequent effects on cellular function and organismal health.
Analyze how environmental factors can influence gene expression without altering the DNA sequence of an organism.
Analyze how environmental factors can influence gene expression without altering the DNA sequence of an organism.
How do the unique characteristics of prokaryotic cells enable them to thrive in diverse and extreme environments?
How do the unique characteristics of prokaryotic cells enable them to thrive in diverse and extreme environments?
How does a greater understanding of these biological fundamentals translate to improvement of modern medical technologies and treatments?
How does a greater understanding of these biological fundamentals translate to improvement of modern medical technologies and treatments?
Predict how the presence of specific organelles in plant cells uniquely contributes to their survival in an ecosystem.
Predict how the presence of specific organelles in plant cells uniquely contributes to their survival in an ecosystem.
Formulate a hypothesis on how genetic drift might affect the genetic diversity of a small, isolated population of organisms over time.
Formulate a hypothesis on how genetic drift might affect the genetic diversity of a small, isolated population of organisms over time.
Describe roles of the ribosomes in protein synthesis, comparing its function across both prokaryotic and eukaryotic cells.
Describe roles of the ribosomes in protein synthesis, comparing its function across both prokaryotic and eukaryotic cells.
Propose a scenario to explain how the semi-permeable nature of the cell membrane maintains homeostasis in a changing external environment.
Propose a scenario to explain how the semi-permeable nature of the cell membrane maintains homeostasis in a changing external environment.
Considering cell-to-cell communication, predict how disruptions in cellular signaling pathways can lead to diseases, focusing on an instance where such breakdowns has been investigated.
Considering cell-to-cell communication, predict how disruptions in cellular signaling pathways can lead to diseases, focusing on an instance where such breakdowns has been investigated.
Explain how viruses utilize host cell machinery for their replication, impacting host cell viability and functions.
Explain how viruses utilize host cell machinery for their replication, impacting host cell viability and functions.
Given that mitochondrial diseases often affect multiple organ systems, suggest why these conditions are challenging to diagnose.
Given that mitochondrial diseases often affect multiple organ systems, suggest why these conditions are challenging to diagnose.
Outline role of the Zono Pellusida's function in egg and what it's structure and composition does for the Oocyte
Outline role of the Zono Pellusida's function in egg and what it's structure and composition does for the Oocyte
Explain how both sperm cells and oocyte structure impacts polyspermy and how it contributes to healthy process.
Explain how both sperm cells and oocyte structure impacts polyspermy and how it contributes to healthy process.
Given that Mitochondria DNA (mtDNA) diseases are mostly inherited, why are both Mitochondrial Replacement Therapy and Pronuclear Transfer methods?
Given that Mitochondria DNA (mtDNA) diseases are mostly inherited, why are both Mitochondrial Replacement Therapy and Pronuclear Transfer methods?
Describe in simplistic terms what the "Pronucleus" does (in the scope of oocyte) and why scientists need to manipulate.
Describe in simplistic terms what the "Pronucleus" does (in the scope of oocyte) and why scientists need to manipulate.
Describe the ethical and general processes of Pronuclear Transfer and explain if this is generally widespreaded.
Describe the ethical and general processes of Pronuclear Transfer and explain if this is generally widespreaded.
Why does mitochondrial dysfunction present challenges in medical diagnoses and treatment. Provide specific examples of the affected tissue types to illustrate
Why does mitochondrial dysfunction present challenges in medical diagnoses and treatment. Provide specific examples of the affected tissue types to illustrate
How can the principles of normal embryological development be utilized to improve the efficacy of in vitro fertilization (IVF) for human infertility. Elaborate on how this ensures future zygote survivability
How can the principles of normal embryological development be utilized to improve the efficacy of in vitro fertilization (IVF) for human infertility. Elaborate on how this ensures future zygote survivability
Compare the approaches to prevent Mitochondrial related inheritance to 1900 medicine and provide a future insight for how new research may shift techniques.
Compare the approaches to prevent Mitochondrial related inheritance to 1900 medicine and provide a future insight for how new research may shift techniques.
Discuss how lifestyle factors and environmental exposures might affect the integrity of a cell's DNA and therefore alter overall human wellbeing and function.
Discuss how lifestyle factors and environmental exposures might affect the integrity of a cell's DNA and therefore alter overall human wellbeing and function.
Describe the role of the scientist in current day modern gene editing and how this would benefit scientific progression.
Describe the role of the scientist in current day modern gene editing and how this would benefit scientific progression.
How does a cell's structure relate to its function as the fundamental unit of life?
How does a cell's structure relate to its function as the fundamental unit of life?
What are the two core tenets of the cell theory as modified by Virchow?
What are the two core tenets of the cell theory as modified by Virchow?
How do eukaryotic and prokaryotic cells differ in terms of their nuclear organization and what terms describe them?
How do eukaryotic and prokaryotic cells differ in terms of their nuclear organization and what terms describe them?
What role does the cytoplasm play in both plant and animal cells?
What role does the cytoplasm play in both plant and animal cells?
In addition to genomic DNA, what other type of DNA is found in many bacteria, and what unique property does it confer?
In addition to genomic DNA, what other type of DNA is found in many bacteria, and what unique property does it confer?
What are the key differences in the DNA replication process between eukaryotic and prokaryotic cells?
What are the key differences in the DNA replication process between eukaryotic and prokaryotic cells?
How does the structural organization of genetic material differ between eukaryotic and prokaryotic cells?
How does the structural organization of genetic material differ between eukaryotic and prokaryotic cells?
What is the role of extensive compartmentalization in eukaryotic cells, and how is it achieved?
What is the role of extensive compartmentalization in eukaryotic cells, and how is it achieved?
How does the fluid mosaic model describe the structure and function of the cell membrane?
How does the fluid mosaic model describe the structure and function of the cell membrane?
How are membrane proteins classified based on the ease of their extraction, and where do they typically reside within the membrane?
How are membrane proteins classified based on the ease of their extraction, and where do they typically reside within the membrane?
What advantages does the quasi-fluid nature of the lipid bilayer confer to the cell?
What advantages does the quasi-fluid nature of the lipid bilayer confer to the cell?
What key roles does the non-living rigid cell wall perform for plant and fungal cells?
What key roles does the non-living rigid cell wall perform for plant and fungal cells?
What is the primary function of ribosomes, and in which cellular locations are they typically found?
What is the primary function of ribosomes, and in which cellular locations are they typically found?
What is the main purpose of mitochondria, and what unique genetic material do they possess?
What is the main purpose of mitochondria, and what unique genetic material do they possess?
How do nuclear pores facilitate communication between the nucleus and cytoplasm?
How do nuclear pores facilitate communication between the nucleus and cytoplasm?
Briefly explain the central dogma of molecular biology, detailing the flow of genetic information.
Briefly explain the central dogma of molecular biology, detailing the flow of genetic information.
What is the significance of having chromosomes that are characteristic for a species?
What is the significance of having chromosomes that are characteristic for a species?
What does it mean for a cell to be diploid or haploid, and how are these states represented?
What does it mean for a cell to be diploid or haploid, and how are these states represented?
Why is it necessary for gametes to be haploid cells?
Why is it necessary for gametes to be haploid cells?
What are the fundamental differences between mitosis and meiosis in terms of their purpose and final products?
What are the fundamental differences between mitosis and meiosis in terms of their purpose and final products?
Describe the process of gametogenesis and the types of cells that are produced as a result.
Describe the process of gametogenesis and the types of cells that are produced as a result.
What is the purpose of the acrosome reaction during fertilization?
What is the purpose of the acrosome reaction during fertilization?
What are some important features of Zygotes, and how are they related ?
What are some important features of Zygotes, and how are they related ?
What is mitochondrial replacement therapy (MRT), and what is its primary purpose?
What is mitochondrial replacement therapy (MRT), and what is its primary purpose?
Explain how pronuclear transfer works?
Explain how pronuclear transfer works?
What ethical concerns are raised by the creation of 'three-parent babies'?
What ethical concerns are raised by the creation of 'three-parent babies'?
What key features distinguish plant cells from animal cells?
What key features distinguish plant cells from animal cells?
What cell organelles play play the most significant role protein synthesis?
What cell organelles play play the most significant role protein synthesis?
What organelles contains DNA other than the nucleus?
What organelles contains DNA other than the nucleus?
What statements can be used for DNA Barcoding ?
What statements can be used for DNA Barcoding ?
Flashcards
Cell
Cell
The fundamental structural and functional unit of all living organisms, capable of independent existence and performing essential functions.
Cell Theory
Cell Theory
States that all living organisms are composed of cells and their products, and that all cells arise from pre-existing cells.
Nucleus
Nucleus
A dense, membrane-bound structure within a cell containing chromosomes with DNA.
Eukaryotic Cells
Eukaryotic Cells
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Prokaryotic Cells
Prokaryotic Cells
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Cytoplasm
Cytoplasm
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Ribosomes
Ribosomes
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Prokaryotic examples
Prokaryotic examples
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Eukaryotic feature
Eukaryotic feature
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Cell Wall
Cell Wall
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Plant cell wall
Plant cell wall
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Cell walls functions
Cell walls functions
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Cell Organelles
Cell Organelles
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Rough Endoplasmic Reticulum
Rough Endoplasmic Reticulum
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Lysosomes
Lysosomes
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Smooth Endoplasmic Reticulum
Smooth Endoplasmic Reticulum
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Golgi Apparatus
Golgi Apparatus
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Storage
Storage
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Mitochondria
Mitochondria
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Chloroplast
Chloroplast
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Centrosome
Centrosome
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Nuclear Pores
Nuclear Pores
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Nuclear matrix
Nuclear matrix
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Nucleolus
Nucleolus
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Chromosomes
Chromosomes
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Humans and cells
Humans and cells
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Haploid
Haploid
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Diploid
Diploid
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Cell division
Cell division
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Sperm and Aum
Sperm and Aum
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Mitosis vs Meiosis
Mitosis vs Meiosis
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Mitosis vs Meiosis pt2
Mitosis vs Meiosis pt2
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Diploid produces the cells while haploid makes 1/2 DNA
Diploid produces the cells while haploid makes 1/2 DNA
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Gametes Functions
Gametes Functions
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Zygote Features
Zygote Features
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Replace mother defective mitochondria
Replace mother defective mitochondria
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Reconstructed Egg Technology
Reconstructed Egg Technology
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3 parents offspring
3 parents offspring
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Pronuclear transfer
Pronuclear transfer
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Plant and animal differences.
Plant and animal differences.
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Plant and animal vacuoles.
Plant and animal vacuoles.
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Other Parts vs, Protien
Other Parts vs, Protien
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Organelle DNA
Organelle DNA
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DNA barcoding
DNA barcoding
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Study Notes
Cell: The Fundamental Unit of Life
- Unicellular organisms exhibit independent existence.
- They also perform life's essential functions.
- A complete cell structure is essential for independent living.
- Cells are the fundamental structural and functional units of all living organisms.
- Anton Von Leeuwenhoek was the first to observe and describe a live cell.
- Robert Brown discovered the nucleus.
Cell Theory
- The cell theory was formulated by Schleiden and Schwann and later modified by Virchow.
- All living organisms consist of cells and their products.
- All cells arise from pre-existing cells.
Basic Structure of a Cell
- Each cell has a nucleus, a dense, membrane-bound structure.
- The nucleus contains chromosomes, the structures that contain genetic material, like DNA.
- Cells with membrane-bound nuclei are called eukaryotic cells.
- Cells lacking membrane-bound nuclei are called prokaryotic cells.
- Cytoplasm, a semi-fluid matrix, occupies the volume both prokaryotic and eukaryotic cells.
- The cytoplasm is the main site of cellular activities in both plant and animal cells.
- Prokaryotic cells are in the kingdom Monera.
- Ribosomes are non-membrane-bound organelles found in all cells.
- The term prokaryotic can be broken down to understand it: Pro + Eu + karyon
Prokaryotic Cells
- Examples of prokaryotic cells include bacteria, blue-green algae, mycoplasma, and PPLO.
- Prokaryotes have a cell wall around the cell membrane, except for mycoplasma.
- Cytoplasm fills the fluid matrix of the cell.
- Prokaryotes lack a well-defined nucleus.
- The genetic material is naked and not enveloped by a nuclear membrane.
- Genomic DNA in bacteria is typically one circular chromosome.
- Many bacteria have smaller circular DNA molecules called plasmids outside the genomic DNA.
- Plasmid DNA gives unique phenotypic characteristics like antibiotic resistance.
- Nuclear membranes are only present in eukaryotic cells.
Eukaryotic Cells
- Eukaryotic cells have extensive compartmentalization of cytoplasm.
- This compartmentalization occurs through the presence of membrane-bound organelles.
- Eukaryotic cells possess an organized nucleus with a nuclear envelope.
- The genetic material in eukaryotic cells is organized into chromosomes.
- There are 5 kingdoms based on their features: Monera, Protista, Fungi, Plantae, and Animalia.
Cell Membrane
- Mainly composed of lipids and proteins.
- The major lipids are phospholipids, arranged in a bilayer.
- Membrane proteins are classified as integral or peripheral depending on the ease of extraction.
- Peripheral proteins lie on the surface of the membrane.
- Integral proteins are partially or totally buried in the membrane.
- The quasi-fluid nature of the lipid enables lateral movement of proteins.
- It is also enabling cell growth, formation of intercellular junctions, secretion, endocytosis, cell division, etc.
- The membrane is selectively permeable to some molecules.
- Molecules on either side of it are subject to passive and active transport.
Cell Wall
- The cell wall is a non-living rigid structure around the plasma membrane
- It is found in fungi and plants.
- The cell wall provides shape to the cell.
- It also protects the cell from mechanical damage and infection.
- The cell wall facilitates cell-to-cell interaction.
- It acts as a barrier to undesirable macromolecules.
- Algae cell walls are made of cellulose, galactans, and mannans.
- Plant cell walls consist of cellulose, hemicellulose, pectins, and proteins.
Nucleus
- Nuclear pores are passages for RNA and protein molecule movement between the nucleus and cytoplasm.
- The nuclear matrix, or nucleoplasm, contains the nucleolus and chromatin.
- The nucleolus is continuous with the rest of the nucleoplasm and is not membrane-bound.
- One of the functions of Nucleolus is the site for active ribosomal RNA synthesis.
- During cell division, cells show structured chromosomes in place of the nucleus.
Mitochondrial Replacement Therapy (MRT)
- Replaces defective mitochondria with healthy mitochondria.
- Also known as mitochondrial donation: replaces mitochondria in one or more cells to prevent or ameliorate diseases.
- MRT originated as a special form of in vitro fertilization.
- All or some of the future baby's mitochondrial DNA (mtDNA) comes from a third party,
- This technique is used when mothers carry genes for mitochondrial diseases.
Pronuclear Transfer
- This involves the transfer of pronuclei from one zygote to another AFTER fertilization.
Reconstructed Egg Technology
- This is done BEFORE fertilization
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