Podcast
Questions and Answers
Cell surface receptors are _______________ to individual cell types.
Cell surface receptors are _______________ to individual cell types.
specific
Cell surface receptors have three components: external ligand binding domain, _______________ membrane-spanning region, and intracellular domain.
Cell surface receptors have three components: external ligand binding domain, _______________ membrane-spanning region, and intracellular domain.
hydrophobic
Ligand binding to a _______________ receptor triggers an intracellular response.
Ligand binding to a _______________ receptor triggers an intracellular response.
membrane
Ligand binding to a _______________ receptor opens a channel through which specific ions pass through.
Ligand binding to a _______________ receptor opens a channel through which specific ions pass through.
Signup and view all the answers
G proteins are _______________ signaling proteins.
G proteins are _______________ signaling proteins.
Signup and view all the answers
G protein signaling can result in _______________ of the biological response of the cell.
G protein signaling can result in _______________ of the biological response of the cell.
Signup and view all the answers
Cells communicate by soluble chemical ______ e.g. hormones, growth factors, neurotransmitters.
Cells communicate by soluble chemical ______ e.g. hormones, growth factors, neurotransmitters.
Signup and view all the answers
The cell which receives signal is the ______ cell.
The cell which receives signal is the ______ cell.
Signup and view all the answers
Binding of signal to ______ initiates cascade of events which amplifies the signal and produces the desired effect.
Binding of signal to ______ initiates cascade of events which amplifies the signal and produces the desired effect.
Signup and view all the answers
______ receptors are present inside cell cytoplasm and binds to hydrophobic ligands.
______ receptors are present inside cell cytoplasm and binds to hydrophobic ligands.
Signup and view all the answers
The ______ receptor complex moves inside nucleus and binds to specific regions of DNA and promotes/inhibits production of MRNA.
The ______ receptor complex moves inside nucleus and binds to specific regions of DNA and promotes/inhibits production of MRNA.
Signup and view all the answers
The process of ligand binding to receptor and producing the desired effect is an example of ______ regulation.
The process of ligand binding to receptor and producing the desired effect is an example of ______ regulation.
Signup and view all the answers
The ______ subunit of G protein releases GDP and binds GTP.
The ______ subunit of G protein releases GDP and binds GTP.
Signup and view all the answers
The effector domain contains a catalytic region with ______ kinase activity.
The effector domain contains a catalytic region with ______ kinase activity.
Signup and view all the answers
Ligand binds to receptor —> conformational change to receptor —> interacts with ______ protein.
Ligand binds to receptor —> conformational change to receptor —> interacts with ______ protein.
Signup and view all the answers
Enzyme linked receptors are single chain transmembrane proteins with three domains: ______-binding domain, alpha-helical domain, and effector domain.
Enzyme linked receptors are single chain transmembrane proteins with three domains: ______-binding domain, alpha-helical domain, and effector domain.
Signup and view all the answers
When the ligand leaves the receptor —> receptor returns to initial state —> GTP is hydrolyzed to ______.
When the ligand leaves the receptor —> receptor returns to initial state —> GTP is hydrolyzed to ______.
Signup and view all the answers
Association leads to activation of ______ kinase ~> phosphorylation of tyrosine residues.
Association leads to activation of ______ kinase ~> phosphorylation of tyrosine residues.
Signup and view all the answers
