Cell Signaling Basics

Cells communicate by soluble chemical signals e.g. ______, growth factors, neurotransmitters

Cell which receives signal is the ______ cell

Binding of signal to ______ initiates cascade of events which amplifies the signal

______ receptors bind and respond to hydrophobic ligands which can travel through the cell membrane

Ligand binds internal receptor ~— ______ binding site is exposed on the receptor

Receptor forms ______ transduction i.e.

Cell surface receptors are specific to individual ______ types

Ligand binds to a ______ receptor ligand-receptor complex triggers intracellular response

Ligand binding opens a ______ through which specific ions pass through

G proteins are ______ signaling proteins

Heterotrimeric G proteins have three ______: a, B, y

Activation of second ______ messenger + production