Cell Reprogramming Techniques Quiz
18 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What type of cells contain all the necessary genetic information to generate a whole organism?

  • Differentiated somatic cells (correct)
  • Mouse fibroblasts
  • iPSCs
  • Master cells
  • Which process involves the egg cell reprogramming somatic cell nuclei?

  • Somatic cell cloning
  • Cell reprogramming (correct)
  • ESC maintenance
  • Cell differentiation
  • What is the main purpose of using Integrating systems or Non-integrating systems in generating iPSCs?

  • Delivery of transcription factors (correct)
  • Cell differentiation
  • Cell reprogramming
  • ESC maintenance
  • Which of the following transcription factors was NOT part of the pool of 24 factors used for generating iPSCs?

    <p>Antennapedia</p> Signup and view all the answers

    What was the year when the discovery of 'master' Transcription Factors that determine and restrict cell fate to a specific lineage was made?

    <p>1987</p> Signup and view all the answers

    What is the key process that differentiates iPSCs from other cell types?

    <p>Cell differentiation</p> Signup and view all the answers

    Which specific genes are involved in determining morphological and functional specialization of differentiated cells?

    <p>Oct3/4, Sox2, Klf4, c-Myc</p> Signup and view all the answers

    What is the key information needed to differentiate stem cells into specific cell types in the laboratory?

    <p>Expression of master transcription factors</p> Signup and view all the answers

    Which process involves the expression of genes associated with specific functions of each cell, like actin and myosin?

    <p>Cell reprogramming</p> Signup and view all the answers

    What does silencing of pluripotency genes expression contribute to in the context of stem cell differentiation?

    <p>Differentiation potential</p> Signup and view all the answers

    Which factor is essential for skeletal muscle differentiation?

    <p>MyoD</p> Signup and view all the answers

    What dictates the cellular morphology and function based on the combination of activated or repressed genes?

    <p>Waddington's epigenetic landscape</p> Signup and view all the answers

    Which type of stem cells are derived from the inner cell mass of the blastocyst?

    <p>Embryonic stem cells (ESCs)</p> Signup and view all the answers

    What is the key feature of induced pluripotent stem cells (iPSCs)?

    <p>Pluripotency after reprogramming</p> Signup and view all the answers

    Which scientific discovery contributed to the development of induced pluripotent stem cells (iPSCs)?

    <p>Identification of master transcription factors in 1987</p> Signup and view all the answers

    What is the significance of the 'Yamanaka factors' in stem cell research?

    <p>Responsible for maintaining ESC pluripotency</p> Signup and view all the answers

    What did studies on reprogramming by nuclear transfer or somatic cell cloning demonstrate?

    <p>Differentiated cells contain required genetic information</p> Signup and view all the answers

    Which type of stem cells are sourced from a variety of tissues and organs, including fetal and adult sources?

    <p>Non-embryonic stem cells</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser