Cell Reprogramming Techniques Quiz
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Questions and Answers

What type of cells contain all the necessary genetic information to generate a whole organism?

  • Differentiated somatic cells (correct)
  • Mouse fibroblasts
  • iPSCs
  • Master cells

Which process involves the egg cell reprogramming somatic cell nuclei?

  • Somatic cell cloning
  • Cell reprogramming (correct)
  • ESC maintenance
  • Cell differentiation

What is the main purpose of using Integrating systems or Non-integrating systems in generating iPSCs?

  • Delivery of transcription factors (correct)
  • Cell differentiation
  • Cell reprogramming
  • ESC maintenance

Which of the following transcription factors was NOT part of the pool of 24 factors used for generating iPSCs?

<p>Antennapedia (D)</p> Signup and view all the answers

What was the year when the discovery of 'master' Transcription Factors that determine and restrict cell fate to a specific lineage was made?

<p>1987 (D)</p> Signup and view all the answers

What is the key process that differentiates iPSCs from other cell types?

<p>Cell differentiation (D)</p> Signup and view all the answers

Which specific genes are involved in determining morphological and functional specialization of differentiated cells?

<p>Oct3/4, Sox2, Klf4, c-Myc (B)</p> Signup and view all the answers

What is the key information needed to differentiate stem cells into specific cell types in the laboratory?

<p>Expression of master transcription factors (B)</p> Signup and view all the answers

Which process involves the expression of genes associated with specific functions of each cell, like actin and myosin?

<p>Cell reprogramming (C)</p> Signup and view all the answers

What does silencing of pluripotency genes expression contribute to in the context of stem cell differentiation?

<p>Differentiation potential (D)</p> Signup and view all the answers

Which factor is essential for skeletal muscle differentiation?

<p>MyoD (C)</p> Signup and view all the answers

What dictates the cellular morphology and function based on the combination of activated or repressed genes?

<p>Waddington's epigenetic landscape (C)</p> Signup and view all the answers

Which type of stem cells are derived from the inner cell mass of the blastocyst?

<p>Embryonic stem cells (ESCs) (D)</p> Signup and view all the answers

What is the key feature of induced pluripotent stem cells (iPSCs)?

<p>Pluripotency after reprogramming (D)</p> Signup and view all the answers

Which scientific discovery contributed to the development of induced pluripotent stem cells (iPSCs)?

<p>Identification of master transcription factors in 1987 (C)</p> Signup and view all the answers

What is the significance of the 'Yamanaka factors' in stem cell research?

<p>Responsible for maintaining ESC pluripotency (D)</p> Signup and view all the answers

What did studies on reprogramming by nuclear transfer or somatic cell cloning demonstrate?

<p>Differentiated cells contain required genetic information (A)</p> Signup and view all the answers

Which type of stem cells are sourced from a variety of tissues and organs, including fetal and adult sources?

<p>Non-embryonic stem cells (D)</p> Signup and view all the answers
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