Cell Receptor Desensitization Mechanisms
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Cell Receptor Desensitization Mechanisms

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Questions and Answers

What is the term for the phenomenon where repeated administration of a drug results in a diminished effect?

  • Endocytosis
  • Down-regulation
  • Tachyphylaxis (correct)
  • Desensitization

    • How do spare receptors contribute to signal duration and intensity?

  • The receptors may be recycled to the cell surface
  • A single ligand receptor complex can interact with many G proteins (correct)
  • Receptors become unresponsive to the ligand
  • Binding of the agonist results in molecular changes in the membrane-bound receptors

    • What happens to receptors when they undergo endocytosis?

  • They are down-regulated
  • They become more sensitive to the ligand
  • They are sequestered from further agonist interaction (correct)
  • They initiate cell death

    • What characterizes systems that exhibit spare receptors behavior?

    <p>They have the ability to amplify signal duration &amp; intensity</p> Signup and view all the answers

    What is one of the mechanisms evolved to protect a cell from excessive stimulation?

    <p>The receptors may be still &amp; become unresponsive to the ligand.</p> Signup and view all the answers

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