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Questions and Answers
What is the term for the phenomenon where repeated administration of a drug results in a diminished effect?
What is the term for the phenomenon where repeated administration of a drug results in a diminished effect?
- Endocytosis
- Down-regulation
- Tachyphylaxis (correct)
- Desensitization
How do spare receptors contribute to signal duration and intensity?
How do spare receptors contribute to signal duration and intensity?
- The receptors may be recycled to the cell surface
- A single ligand receptor complex can interact with many G proteins (correct)
- Receptors become unresponsive to the ligand
- Binding of the agonist results in molecular changes in the membrane-bound receptors
What happens to receptors when they undergo endocytosis?
What happens to receptors when they undergo endocytosis?
- They are down-regulated
- They become more sensitive to the ligand
- They are sequestered from further agonist interaction (correct)
- They initiate cell death
What characterizes systems that exhibit spare receptors behavior?
What characterizes systems that exhibit spare receptors behavior?
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What is one of the mechanisms evolved to protect a cell from excessive stimulation?
What is one of the mechanisms evolved to protect a cell from excessive stimulation?
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