Cell & Molecular Biology: Mendel's Genetics

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Questions and Answers

What type of inheritance is indicated by a phenotype being influenced by two or more genes?

  • Codominance
  • Monogenic inheritance
  • Polygenic inheritance (correct)
  • X-linked inheritance

What is the expected phenotypic ratio among F2 offspring resulting from independent assortment in the provided example?

  • 9 black to 3 brown to 3 white (correct)
  • 3 black to 1 brown to 3 white
  • 9 black to 3 brown to 4 white
  • 1 black to 1 brown to 1 white

What does the term 'norm of reaction' refer to?

  • Phenotypic variations determined solely by genetics
  • An exclusive influence of developmental processes on phenotype
  • A rigidly defined phenotype based on genotype
  • The range of phenotypic possibilities influenced by environment (correct)

Which of the following statements about polygenic characters is true?

<p>They often follow a bell-shaped curve in distribution. (B)</p> Signup and view all the answers

How can environmental factors influence phenotype?

<p>They can lead to changes in characteristics like height and skin color. (B)</p> Signup and view all the answers

What is the main flaw in the blending hypothesis of heredity?

<p>It proposes that genetic material mixes like paint. (B), It accounts for traits skipping generations. (D)</p> Signup and view all the answers

Which hypothesis suggests that traits retain their identities during inheritance?

<p>Particulate hypothesis (D)</p> Signup and view all the answers

What term do geneticists use to refer to heritable features?

<p>Characters (D)</p> Signup and view all the answers

Why did Mendel choose to work with garden peas for his experiments?

<p>They could self-fertilize easily. (B)</p> Signup and view all the answers

What describes the variants for a character, such as flower color?

<p>Traits (B)</p> Signup and view all the answers

Mendel's experiments demonstrated that heritable traits could be traced through generations by tracking:

<p>Discrete characters. (B)</p> Signup and view all the answers

What is the concept of the 'gene idea' primarily associated with?

<p>The passing of discrete heritable traits unchanged. (A)</p> Signup and view all the answers

Which color of flowers did Mendel use in his experiments to study inheritance?

<p>Purple and white (C)</p> Signup and view all the answers

What term describes the process of crossing two true-breeding varieties in Mendel's experiments?

<p>Hybridization (B)</p> Signup and view all the answers

Which generation results from the cross-pollination of the P generation?

<p>F1 generation (D)</p> Signup and view all the answers

According to Mendel's Law of Segregation, what happens to alleles during gamete production?

<p>They segregate into separate gametes. (A)</p> Signup and view all the answers

What do we call the offspring produced by self-pollinating the F1 generation?

<p>F2 generation (D)</p> Signup and view all the answers

If an organism has two different alleles for a character, what is true about its appearance?

<p>The organism is considered heterozygous. (A), The dominant allele is fully expressed. (B)</p> Signup and view all the answers

What defines an organism as being homozygous?

<p>It has a pair of identical alleles. (B)</p> Signup and view all the answers

What are the fundamental principles of heredity that Mendel identified through the F2 generation?

<p>Law of Segregation and Law of Independent Assortment (C)</p> Signup and view all the answers

What happens to variations in inherited characters?

<p>They are controlled by alternative versions of genes. (B)</p> Signup and view all the answers

What will happen to the alleles if the organism is heterozygous for a trait?

<p>Only the dominant allele will be expressed. (D)</p> Signup and view all the answers

In Mendel's experiments with pea plants, what characteristics did he primarily study?

<p>Flower color and seed shape (B)</p> Signup and view all the answers

What is the genetic makeup of an organism called?

<p>Genotype (A)</p> Signup and view all the answers

Which of the following genotypes would produce a purple flower phenotype?

<p>Both A and C (A)</p> Signup and view all the answers

In the context of a testcross, what does crossing a purple pea flower (unknown genotype) with a white flowered pea (pp) help determine?

<p>The genotype of the purple flower (A)</p> Signup and view all the answers

In a dihybrid cross involving seed color and seed shape, which alleles are dominant?

<p>Yellow seeds and round shape (B)</p> Signup and view all the answers

What is the significance of dominance and recessiveness in relation to phenotypes?

<p>They allow for identical phenotypes with different genotypes. (B)</p> Signup and view all the answers

Which of the following is NOT true regarding a heterozygous organism?

<p>It exhibits a recessive phenotype. (C)</p> Signup and view all the answers

When crossing a true breeding purple flowered pea and a white flowered pea, what is the expected phenotype of the offspring?

<p>All purple flowers (C)</p> Signup and view all the answers

Which concept explains whether two traits, like seed color and shape, are transmitted independently?

<p>Dihybrid inheritance (C)</p> Signup and view all the answers

What does the phenotype of an organism reflect?

<p>The observable characteristics of the organism (C)</p> Signup and view all the answers

In a genetic cross where the offspring display a combination of traits from both parents, what is the genotypic ratio generally expected in a dihybrid cross?

<p>9:3:3:1 (A)</p> Signup and view all the answers

What phenotypic ratio results from the independent assortment of two characters in the F1 generation?

<p>9:3:3:1 (C)</p> Signup and view all the answers

What is the term used for different forms of a gene that can exist in a population?

<p>Alleles (B)</p> Signup and view all the answers

In incomplete dominance, what phenotype results from the crossing of red and white snapdragons?

<p>Pink flowers (A)</p> Signup and view all the answers

What happens when individuals with the IA and IB alleles are crossed?

<p>Offspring can be either type A, B, or AB (D)</p> Signup and view all the answers

Which of the following describes the phenomenon where both alleles are fully expressed in the phenotype?

<p>Codominance (B)</p> Signup and view all the answers

What is pleiotropy in genetics?

<p>Multiple phenotypic effects by a single gene (C)</p> Signup and view all the answers

In the context of epistasis, what does a homozygous recessive genotype at one gene locus affect?

<p>It can mask the expression of another gene (A)</p> Signup and view all the answers

What is the expected phenotype ratio of the F2 generation when F1 hybrids of snapdragons are crossed?

<p>1 red: 2 pink: 1 white (D)</p> Signup and view all the answers

How can mismatch in blood type during transfusion affect the recipient?

<p>It can result in clumping and potential death (A)</p> Signup and view all the answers

What is meant by the term 'dominance' in genetics?

<p>One allele masks the expression of another allele (C)</p> Signup and view all the answers

Flashcards

Heritable trait

A characteristic that can be passed down from parents to offspring, such as eye color, hair color, or flower color.

Blending hypothesis

The idea that genetic material mixes like paint, resulting in a uniform population over generations.

Particulate hypothesis (gene idea)

Traits passed down from parents to offspring retain their separate identities, like marbles in a bucket.

Character

A heritable feature, like flower color or plant height.

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Trait

A specific variant of a character, like purple or white flowers.

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Garden peas

Gregor Mendel's choice of organism for his inheritance studies, due to their diverse traits and controlled reproduction.

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Self-fertilization

The process where a plant fertilizes itself.

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Discrete characters

Traits that have only two clear possibilities, like purple or white flowers.

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Heterozygous

An organism with two different alleles for a particular gene. For example, a pea plant with the genotype Pp, where 'P' represents the dominant allele for purple flowers and 'p' represents the recessive allele for white flowers.

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Phenotype

The physical appearance or observable traits of an organism, determined by its genotype.

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Genotype

The genetic makeup of an organism, represented by the combination of alleles it possesses.

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Testcross

A cross between an individual with an unknown genotype and a homozygous recessive individual to determine the unknown genotype. This is done to determine whether the dominant phenotype of the unknown individual is due to a homozygous dominant or heterozygous genotype.

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Dihybrid Cross

A cross between two individuals that differ in two or more characters. For example, crossing a pea plant with yellow round seeds (YYRR) with a plant having green wrinkled seeds (yyrr).

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Law of Independent Assortment

The alleles for different characters (traits) are transmitted independently of one another during gamete formation. This means that the inheritance of one trait does not influence the inheritance of another.

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True-breeding

A variety of plant that, when self-pollinated, produces only offspring with the same trait.

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P generation

The parent generation in a breeding experiment, involving two contrasting, true-breeding varieties.

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Hybridization

The mating or crossing of two different varieties of organisms, often contrasting in a specific trait.

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F1 generation

The offspring resulting from the cross-pollination of two true-breeding parent plants (P generation).

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F2 generation

The offspring produced by the self-pollination of F1 generation plants.

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Law of Segregation

The principle that during gamete formation, the two alleles for a character separate, so that each gamete receives only one allele.

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Alleles

Alternative forms of a gene that account for variations in a trait.

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Dominant allele

The allele that expresses its trait even when paired with a different allele.

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Recessive allele

The allele that does not express its trait when paired with a dominant allele.

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Homozygous

An organism with two identical alleles for a trait.

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Quantitative character

A character with a wide range of variation, like human height or skin color, rather than just two or more distinct possibilities.

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Polygenic inheritance

The inheritance pattern where multiple genes contribute to a single trait, leading to a range of phenotypes.

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Additive effect

The effect of multiple genes on a single trait, often resulting in a bell-shaped distribution of phenotypes.

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Norm of reaction

The range of phenotypic possibilities for a given genotype, influenced by the environment.

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Multifactorial characters

Traits influenced by both genetic and environmental factors.

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Incomplete Dominance

A type of inheritance where the F1 hybrids have a phenotype that is a blend of the two parental phenotypes, resulting in an intermediate appearance.

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Codominance

A type of inheritance where both alleles are expressed separately in the phenotype, leading to a combined effect.

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Pleiotropy

The ability of a single gene to influence multiple phenotypic traits.

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Epistasis

A situation where one gene's expression masks the expression of another gene at a different locus.

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Multiple Alleles

A form of inheritance where a single gene has more than two allelic forms.

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Gene Expression, Environmental Effects

The situation where a gene's expression is modified by factors other than its alleles, such as environmental factors.

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Independent Assortment

The principle that during gamete formation, alleles of different genes separate independently of one another.

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Study Notes

Cell & Molecular Biology - Mendel, Genes & Chromosomal Inheritance

  • Mendel's work focused on inheritance using garden peas
  • Heritable traits, such as eye color, hair color, were observed in populations
  • The "blending" hypothesis proposes that genetic material mixes like paint
  • This hypothesis contradicts everyday observations and doesn't explain traits skipping generations
  • An alternative is the "particulate" hypothesis (gene idea): parents pass discrete traits like marbles, not blending
  • Genes are passed on to generations without dilution
  • Geneticists use "character" for heritable features like flower color
  • Each variant of a character (e.g., purple or white flowers) is called a "trait"
  • Mendel's pea experiments utilized controlled plant breeding with self-fertilizing pea plants
  • Mendel tracked discrete traits with distinct alternatives ("either-or" traits), like purple or white flowers
  • "True-breeding" varieties meant all offspring were of the same variety when self-pollinated
  • Mendel's experiments involved hybridization: mating two contrasting varieties
  • The hybrid offspring were called the F₁ generation
  • F₁ generations were allowed to pollinate creating F₂ offspring
  • Observations of F₂ generation revealed segregation and independent assortment
  • Research reveals that the two alleles for a trait separate when gametes are formed
  • If alleles differ, one (dominant) is expressed; the other, recessive, has minimal visible effect
  • Alleles are segregated during gamete production
  • A testcross involves crossing a plant with a known genotype that is recessive for a trait
  • This helps determine the genotype of a plant with an unknown genotype
  • A dihybrid cross tracks two characters, such as seed color and shape. Resulting genotypes/phenotypes follow a 9:3:3:1 ratio which proves traits segregate independently
  • Modern genetics has extended beyond Mendel's initial observations
  • Traits are more complex (not simple either/or) with various types of dominance
  • Incomplete dominance leads to a middle ground phenotype (e.g., pink snapdragons)
  • Codominance means both alleles are expressed (e.g., human blood types)
  • Multiple alleles occur for a gene impacting phenotypes (e.g., ABO blood groups)
  • Polygenic traits have multiple genes contributing to a phenotype (e.g., human skin color)
  • Pleiotropy is the ability of a single gene to affect multiple traits
  • Epistasis is when one gene's action influences another gene's expressed phenotype (e.g., coat color in mice)
  • The environment influences the expression of the genotype resulting in phenotypic variation and the norm of reaction

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