36 Questions
Which of the following is NOT a function of the cell membrane?
Separating activities of the cell into different areas
What is the principal function of the 'lipid bilayer' in the biological membrane?
To form a permeability barrier
Which of the following is NOT a membrane-bound organelle?
Lysosome
Which type of inhibition does not change the affinity of the enzyme for the substrate?
Non-competitive inhibition
Which type of inhibition reduces the maximum velocity (Vmax) of the enzyme reaction?
Non-competitive inhibition
Which type of inhibition follows Michaelis-Menten kinetics?
Competitive inhibition
Which of the following is NOT a characteristic of the phospholipid bilayer?
It allows hydrophilic molecules to pass through spontaneously
Which of the following is the most hydrophobic component of the membrane?
Cholesterol
Which type of membrane protein spans the entire membrane?
Transmembrane proteins
What is the function of peripheral membrane proteins?
Attachment to cytoskeleton
Which of the following is NOT a requirement for transport across the membrane?
Diffusion
Which of the following is an example of primary active transport?
Na+/K+ pump
What is the Michaelis constant (Km) in enzyme kinetics?
The substrate concentration at ½ Vmax
What type of inhibition occurs when an inhibitor binds to the same site as the substrate and competes for access?
Competitive inhibition
Which of the following routes of administration is best for larger volumes and when faster absorption is desired?
Intravenous
Which of the following factors can affect the rate of drug absorption from the gut?
All of the above
Which of the following routes of administration avoids first-pass metabolism?
Intravenous
Which of the following is NOT a characteristic of oral administration?
Avoids first-pass metabolism
Which of the following is NOT one of the four key processes involved in pharmacokinetics?
Excretion
What is the term used to define the transfer of a drug from the site of administration to the general circulation?
Absorption
Which of the following is NOT a route of drug administration?
Excretion
What is the term used to describe the irreversible loss of unchanged drug from the body?
Excretion
Which route of administration is most suitable for lipid-soluble drugs and expensive bronchodilators?
Inhalation
Which of the following is NOT an advantage of various routes of administration?
Avoids first pass metabolism
What determines the route of administration?
All of the above
What is bioavailability?
The fraction of the administered dose that reaches the systemic circulation as intact drug
Which of the following is NOT a major step of information processing in biology from storage in the form of DNA through to generation of pure protein?
Mutation
Which of the following is NOT a type of bond that holds DNA together?
Peptide bond
Which of the following is NOT a fundamental element of chromosomes in the human genome?
Exons
Which of the following modifications promotes relaxation of chromatin structure?
Acetylation of specific histone residues
Which of the following regions of DNA is always in the heterochromatin form?
Centromeres
What is the role of Histone Deacetylases (HDACs) in gene expression?
They promote DNA condensation
Which of the following statements about DNA is correct?
The sugar-phosphate backbone is on the exterior and the purine and pyrimidine bases are on the interior
Which of the following is NOT a force holding DNA together?
Base stacking
Which of the following is the most basic repeating structural unit of chromatin?
Nucleosome
Which of the following is NOT a type of chromatin?
Solenoid
Test your knowledge on the transport of DNA, proteins, and other molecules across the cell membrane. Explore the energy and structural requirements for transport, including diffusion, active transport, and bulk/vesicular transport. Learn about the role of channel and carrier proteins, ATP, ion gradients, vesicles, membrane fusion, and more.
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