10 Questions
What are the types of passive transport across the cell membrane?
Diffusion, Osmosis, Facilitated diffusion
What is the cell membrane permeable to?
$H_2O$, Gases (O2, CO2, N2), Lipids
What drives the movement of compounds across the cell membrane?
Both chemical and electrical forces (electrochemical force)
What are factors affecting the rate of transport across the cell membrane?
The concentration gradient, The compound permeability to the membrane, The type and number of charges present on the compound
What are examples of active transport across the cell membrane?
$Pumps$, phagocytosis, Endocytosis/exocytosis
What is creatinine clearance used to estimate?
Glomerular filtration rate (GFR)
What can early detection of kidney disease help prevent or delay?
Development of complications associated with kidney disease
What does creatinine clearance provide information about?
Efficiency of kidney waste product filtration
What does impaired kidney function lead to in terms of creatinine clearance?
Decreased creatinine clearance
What is important to note about creatinine clearance as an estimation?
It may not provide a complete picture of kidney function
Study Notes
Passive Transport Across the Cell Membrane
- Types of passive transport: diffusion (simple and facilitated), osmosis, and filtration
- Cell membrane is permeable to: small, non-polar molecules, oxygen, carbon dioxide, and water
Movement of Compounds Across the Cell Membrane
- Movement driven by: concentration gradient, temperature, and pressure
Factors Affecting Rate of Transport
- Factors affecting rate of transport: concentration gradient, surface area, temperature, and membrane permeability
Active Transport Across the Cell Membrane
- Examples of active transport: pumps (e.g., sodium-potassium pump), endocytosis, and exocytosis
- Active transport requires energy (ATP)
Creatinine Clearance
- Creatinine clearance used to estimate: glomerular filtration rate (GFR)
- Early detection of kidney disease helps prevent or delay: kidney failure, cardiovascular disease, and other complications
- Creatinine clearance provides information about: kidney function and GFR
- Impaired kidney function leads to decreased creatinine clearance
- Important to note: creatinine clearance is an estimation and may not reflect actual GFR
Test your knowledge on the different types of cell membrane transport, factors affecting transport, passive and active transport, and membrane transport proteins. Learn about the factors that influence the movement of substances across the cell membrane.
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