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Questions and Answers
Which factor does NOT affect the magnitude of diffusion across the cell membrane?
Which factor does NOT affect the magnitude of diffusion across the cell membrane?
- Concentration gradient
- Surface area for diffusion
- Membrane thickness
- Temperature of the cytoplasm (correct)
What is the correct equation representing the net rate of diffusion (J) across the cell membrane?
What is the correct equation representing the net rate of diffusion (J) across the cell membrane?
- J = A * D * X / Ac
- J = D * A * Ac / X (correct)
- J = D / (A * Ac * X)
- J = D * (A + Ac) / X
Which is NOT a mechanism of passive transport across the cell membrane?
Which is NOT a mechanism of passive transport across the cell membrane?
- Osmosis
- Facilitated diffusion
- Primary active transport (correct)
- Simple diffusion
What term describes the movement of molecules from a region of lower concentration to a region of higher concentration?
What term describes the movement of molecules from a region of lower concentration to a region of higher concentration?
Which type of diffusion does NOT involve the assistance of a carrier protein?
Which type of diffusion does NOT involve the assistance of a carrier protein?
Which statement about osmosis is incorrect?
Which statement about osmosis is incorrect?
In which type of active transport is energy directly consumed to move substances across the membrane?
In which type of active transport is energy directly consumed to move substances across the membrane?
What is the purpose of endocytosis in cell membrane transport?
What is the purpose of endocytosis in cell membrane transport?
What factor does NOT influence the net rate of diffusion of oxygen across the pulmonary membrane?
What factor does NOT influence the net rate of diffusion of oxygen across the pulmonary membrane?
Which substances primarily require transport proteins to cross the lipid bilayer?
Which substances primarily require transport proteins to cross the lipid bilayer?
Which statement best describes facilitated diffusion?
Which statement best describes facilitated diffusion?
What process describes the diffusion of ions through ion channels?
What process describes the diffusion of ions through ion channels?
In the context of diffusion, what is the significance of the Donnan effect?
In the context of diffusion, what is the significance of the Donnan effect?
Which of the following substances can diffuse rapidly across the lipid bilayer?
Which of the following substances can diffuse rapidly across the lipid bilayer?
What happens to oxygen diffusion if the area available for diffusion decreases?
What happens to oxygen diffusion if the area available for diffusion decreases?
Which type of molecules utilizes aquaporins for transport across cell membranes?
Which type of molecules utilizes aquaporins for transport across cell membranes?
What is the primary function of the sodium-potassium pump in cellular transport?
What is the primary function of the sodium-potassium pump in cellular transport?
Which characteristic is NOT associated with primary active transport mechanisms?
Which characteristic is NOT associated with primary active transport mechanisms?
How does the sodium-potassium pump contribute to the electrogenic nature of the cell membrane?
How does the sodium-potassium pump contribute to the electrogenic nature of the cell membrane?
In which scenario is solvent drag most appreciable?
In which scenario is solvent drag most appreciable?
What defines the coupling ratio of the sodium-potassium pump?
What defines the coupling ratio of the sodium-potassium pump?
What role does Ca-ATPase play in muscle cells?
What role does Ca-ATPase play in muscle cells?
What is solvent drag primarily associated with in the context of filtration?
What is solvent drag primarily associated with in the context of filtration?
What effect does phosphorylation have in the operation of the sodium-potassium pump?
What effect does phosphorylation have in the operation of the sodium-potassium pump?
What characterizes the process of nonionic diffusion?
What characterizes the process of nonionic diffusion?
What is the definition of osmotic pressure?
What is the definition of osmotic pressure?
Why does a hyperosmolar solution of NaCl exert osmotic effects on cells?
Why does a hyperosmolar solution of NaCl exert osmotic effects on cells?
How does osmosis occur in relation to solute concentration?
How does osmosis occur in relation to solute concentration?
What is true regarding ultrafiltration in capillary walls?
What is true regarding ultrafiltration in capillary walls?
In which scenario would urea not exert an osmotic effect?
In which scenario would urea not exert an osmotic effect?
What prevents the diffusion of weak acids and bases in their ionic forms?
What prevents the diffusion of weak acids and bases in their ionic forms?
What best describes oncotic pressure?
What best describes oncotic pressure?
What role do V-ATPases play in cellular function?
What role do V-ATPases play in cellular function?
Which of the following best describes secondary active transport?
Which of the following best describes secondary active transport?
What process is characterized by the cell membrane folding inward to form a vesicle?
What process is characterized by the cell membrane folding inward to form a vesicle?
What is the primary purpose of the sodium-dependent glucose transport in intestinal cells?
What is the primary purpose of the sodium-dependent glucose transport in intestinal cells?
Which statement regarding the sodium-calcium exchange mechanism is correct?
Which statement regarding the sodium-calcium exchange mechanism is correct?
What is lost during the process of endocytosis?
What is lost during the process of endocytosis?
Which transport system directly influences the electrochemical gradient of sodium in cells?
Which transport system directly influences the electrochemical gradient of sodium in cells?
What is the function of sodium-dependent amino acid transporters in renal cells?
What is the function of sodium-dependent amino acid transporters in renal cells?
Which of the following correctly describes the process of phagocytosis?
Which of the following correctly describes the process of phagocytosis?
What is immediately formed after the invagination of the cell membrane during pinocytosis?
What is immediately formed after the invagination of the cell membrane during pinocytosis?
Which statement about exocytosis is true?
Which statement about exocytosis is true?
Which of the following components plays a crucial role in the docking of secretory vesicles during exocytosis?
Which of the following components plays a crucial role in the docking of secretory vesicles during exocytosis?
In which process are the contents of vacuoles expelled from the cell after digestion?
In which process are the contents of vacuoles expelled from the cell after digestion?
What type of cells are primarily responsible for phagocytosis?
What type of cells are primarily responsible for phagocytosis?
During which process can pinocytic vacuoles either remain unaltered or fuse with lysosomes?
During which process can pinocytic vacuoles either remain unaltered or fuse with lysosomes?
What occurs during the process of cellular defaecation?
What occurs during the process of cellular defaecation?
Flashcards
Diffusion
Diffusion
The movement of molecules from a region of higher concentration to a region of lower concentration, driven by the concentration gradient.
Simple Diffusion
Simple Diffusion
Diffusion that occurs directly across the cell membrane without the help of any membrane proteins.
Facilitated Diffusion
Facilitated Diffusion
Diffusion that requires the assistance of membrane proteins, such as carrier proteins or channel proteins.
Osmosis
Osmosis
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Active Transport
Active Transport
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Primary Active Transport
Primary Active Transport
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Secondary Active Transport
Secondary Active Transport
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Endocytosis
Endocytosis
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Fick's law of diffusion
Fick's law of diffusion
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Selective Permeability of Cell Membrane
Selective Permeability of Cell Membrane
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Concentration Gradient
Concentration Gradient
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Donnan effect
Donnan effect
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Nondiffusible Ions
Nondiffusible Ions
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Lipid Soluble Molecules
Lipid Soluble Molecules
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Filtration
Filtration
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Filtration Coefficient (Kf)
Filtration Coefficient (Kf)
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Solvent Drag
Solvent Drag
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Sodium-Potassium Pump
Sodium-Potassium Pump
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H+ - K+ ATPase
H+ - K+ ATPase
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Ca2+ - ATPase
Ca2+ - ATPase
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V-ATPases
V-ATPases
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F-ATPases
F-ATPases
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SGLT (Sodium-Glucose Linked Transporter)
SGLT (Sodium-Glucose Linked Transporter)
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Sodium-Dependent Calcium Transport
Sodium-Dependent Calcium Transport
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Phagocytosis
Phagocytosis
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Nonionic Diffusion
Nonionic Diffusion
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Osmotic Pressure
Osmotic Pressure
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Oncotic Pressure
Oncotic Pressure
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Hypertonic Solution
Hypertonic Solution
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Hypotonic Solution
Hypotonic Solution
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Ultrafiltration
Ultrafiltration
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What is phagocytosis?
What is phagocytosis?
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Which cells are phagocytic?
Which cells are phagocytic?
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How does phagocytosis work?
How does phagocytosis work?
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What is pinocytosis?
What is pinocytosis?
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How does pinocytosis work?
How does pinocytosis work?
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What is exocytosis?
What is exocytosis?
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How does exocytosis work?
How does exocytosis work?
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What is needed for exocytosis?
What is needed for exocytosis?
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Study Notes
Chapter 3: Membrane Physiology
- Transport across cell membranes is crucial for multicellular organisms
- The internal environment (ECF) composition differs from intracellular fluid (ICF)
- Differences are due to the cell membrane, which regulates the exchange of materials
- Transport occurs via passive and active mechanisms
Passive Transport Mechanisms
-
Diffusion:
- Simple diffusion: Molecules move down their concentration gradient
- Facilitated diffusion: Carrier proteins aid movement down the gradient
- Nonionic diffusion: Movement of uncharged molecules
-
Osmosis: Movement of water across a selectively permeable membrane from an area of higher water concentration to an area of lower concentration
-
Filtration: Movement of small molecules through a membrane due to pressure differences
Active Transport Mechanisms
- Primary active transport: Uses energy (ATP) directly to move molecules against their concentration gradient, exemplified by the sodium-potassium pump.
- The sodium-potassium pump extrudes sodium (3 Na+) and brings in potassium (2 K+)
- Secondary active transport: Uses the electrochemical gradient of one molecule (often Na+) to move another molecule against its gradient.
- Examples include glucose transport
- Endocytosis: Cellular uptake of materials by engulfing them in vesicles
- Types include phagocytosis (engulfing large particles) and pinocytosis (engulfing fluids or dissolved substances)
- Exocytosis: Cellular release of materials by fusing vesicles with the cell membrane
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