Membrane Structure

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Questions and Answers

Which characteristic of phospholipids primarily drives their spontaneous arrangement into bilayers in aqueous solutions?

  • The ability to form strong covalent bonds with water molecules.
  • The amphipathic nature, possessing both hydrophobic and hydrophilic regions. (correct)
  • The high concentration of cholesterol molecules within their structure.
  • The presence of saturated fatty acid tails that repel water.

A researcher is studying a newly discovered unicellular organism and observes that its cell membrane is highly impermeable to a specific polar molecule. Which component of the membrane is primarily responsible for this impermeability?

  • The peripheral proteins embedded within the membrane.
  • The cholesterol molecules interspersed among the phospholipids.
  • The hydrophobic hydrocarbon chains in the lipid bilayer. (correct)
  • The glycoproteins extending from the extracellular surface.

How do integral and peripheral proteins differ in their association with the cell membrane?

  • Integral proteins primarily function in cell signaling, while peripheral proteins are mainly involved in structural support.
  • Integral proteins are found only on the extracellular side, while peripheral proteins are located exclusively on the cytoplasmic side.
  • Integral proteins are permanently embedded within the lipid bilayer, while peripheral proteins are only temporarily associated with the membrane surface. (correct)
  • Integral proteins are loosely associated with the membrane surface, while peripheral proteins are embedded within the lipid bilayer.

Glycoproteins and glycolipids are exclusively located on the extracellular side of the cell membrane. What is the primary role associated with this specific localization?

<p>Involved in cell adhesion and cell recognition processes. (C)</p>
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A scientist introduces a new drug that inhibits the synthesis of cholesterol in cells. How would this drug most likely affect the structure and function of the cell membrane?

<p>Decrease the rigidity and increase the fluidity of the membrane. (D)</p>
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In the fluid mosaic model, which component is responsible for the mosaic arrangement?

<p>The diverse proteins embedded within the phospholipid bilayer. (D)</p>
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Which of the following best describes the behavior of amphipathic molecules in an aqueous environment?

<p>They form structures with their hydrophobic regions shielded from the water. (D)</p>
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How does the presence of unsaturated fatty acids within the phospholipids affect the fluidity of a cell membrane?

<p>It increases fluidity by disrupting the regular packing of phospholipids. (A)</p>
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Which of the following is NOT a typical function of membrane proteins?

<p>Maintaining the impermeability of the membrane to all molecules. (A)</p>
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A cell needs to import a large amount of a polar molecule. Which mechanism would it most likely use?

<p>Facilitated diffusion or active transport via a membrane protein. (D)</p>
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If a cell membrane is treated with an enzyme that destroys the carbohydrates present on the outer surface, what function would be most affected?

<p>The ability to recognize and interact with other cells. (C)</p>
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How does cholesterol contribute to the stability of the cell membrane at high temperatures?

<p>By restricting the movement of phospholipids, preventing excessive fluidity. (D)</p>
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Which environmental change would likely cause the greatest shift in the composition of fatty acids in a cell membrane?

<p>A change in the ambient temperature. (B)</p>
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If a researcher removes all peripheral proteins from a cell membrane, what function is LEAST likely to be affected?

<p>Membrane transport of small ions. (D)</p>
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How do lipid rafts, specialized microdomains within the cell membrane, differ from the surrounding membrane?

<p>They are enriched in cholesterol and sphingolipids, making them less fluid and thicker. (B)</p>
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A cell membrane contains a high proportion of glycolipids. What is the MOST likely function associated with these molecules?

<p>Mediating cell-cell interactions and recognition. (B)</p>
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Which of these processes is LEAST dependent on the fluidity of the cell membrane?

<p>Simple diffusion of small nonpolar molecules across the membrane. (C)</p>
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A certain toxin disrupts the interaction between peripheral proteins and the cell membrane. What is the MOST likely mechanism of action of this toxin?

<p>It modifies the charge or structure of membrane lipids or integral proteins. (A)</p>
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How would a mutation that prevents glycosylation of membrane proteins affect a cell's interactions with its environment?

<p>It would impair cell-cell recognition and adhesion. (B)</p>
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A cell is engineered to produce phospholipids with only saturated fatty acids. How would this alteration MOST likely impact the cell's function?

<p>Reduced ability to perform exocytosis and endocytosis. (D)</p>
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Flashcards

Amphipathic Lipids

Lipids with both hydrophobic and hydrophilic regions which spontaneously form bilayers in water.

Lipid Bilayer

A sheetlike structure composed of two layers of lipid molecules, primarily phospholipids.

Lipid Bilayer Barrier

The lipid bilayer's hydrophobic core restricts passage of large, polar molecules and ions.

Membrane Proteins

Proteins embedded within or attached to the cell membrane's lipid bilayer.

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Integral Proteins

Proteins embedded within the lipid bilayer.

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Peripheral Proteins

Proteins attached to the surface of the lipid bilayer.

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Glycoproteins & Glycolipids

Carbohydrate structures linked to proteins or lipids on the cell membrane's extracellular side.

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Fluid Mosaic Model

A model describing the cell membrane as a fluid lipid bilayer with a mosaic of proteins.

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Study Notes

  • Lipid bilayers form the basis of cell membranes.
  • Phospholipids and other amphipathic lipids spontaneously create continuous, sheet-like bilayers in water.
  • The hydrophobic hydrocarbon chains at the core of a membrane have low permeability to large molecules and hydrophilic particles.
  • Membranes act as effective barriers between aqueous solutions because of the hydrophobic core.
  • Membrane proteins have varied structures, locations, and functions.
  • Integral proteins are embedded within the lipid layers.
  • Peripheral proteins attach to the surface of the bilayer.
  • Carbohydrate structures are linked to proteins or lipids in membranes, and located on the extracellular side
  • Glycoproteins and glycolipids are involved in cell adhesion and cell recognition.
  • The fluid mosaic model includes peripheral and integral proteins, glycoproteins, phospholipids, and cholesterol, with hydrophobic and hydrophilic regions.
  • Phospholipid bilayers form due to the presence of hydrophobic and hydrophilic regions.
  • Amphipathic molecules contain both hydrophobic and hydrophilic regions.

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