Cell Injury, Necrosis, and Apoptosis Quiz
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Questions and Answers

Which type of cell injury results in recovery and reestablishment of cell's health?

  • Hypoxia
  • Irreversible
  • Immune reactions
  • Reversible (correct)
  • Which of the following is NOT a cause of cell injury?

  • Immune reactions
  • Genetic mutations (correct)
  • Hypoxia
  • Aging
  • Which agent may cause cell injury through reduction of oxygen supply to tissues below physiological level?

  • Fungi
  • Hypoxia (correct)
  • Bacteria
  • Viruses
  • What type of immune reaction causes cell injury mediated by antibodies or T-cells directed against exogenous (non-self) antigens?

    <p>Type I hypersensitivity reaction</p> Signup and view all the answers

    What may also cause cell injury apart from nutritional deficiencies and excesses?

    <p>Physical agents</p> Signup and view all the answers

    Which type of cell injury cannot be regained after the removal of physiologic stress and pathologic stimuli?

    <p>Irreversible cell injury</p> Signup and view all the answers

    What is the primary cause of cell injury through reduction of oxygen supply to tissues below physiological level?

    <p>Hypoxia</p> Signup and view all the answers

    Which immune reaction causes cell injury mediated by antibodies or T-cells directed against exogenous (non-self) antigens?

    <p>Hypersensitivity reactions</p> Signup and view all the answers

    What may cause cell injury apart from nutritional deficiencies and excesses?

    <p>Chemicals and drugs</p> Signup and view all the answers

    Which agent can cause cell injury through various forms such as viruses, bacteria, fungi, and protozoa?

    <p>Microorganisms</p> Signup and view all the answers

    Which of the following is an example of a normal cellular constituent accumulated in excess?

    <p>Lipid</p> Signup and view all the answers

    What is the primary cause of accumulation of an abnormal exogenous substance in cells?

    <p>Inability to transport the substance to other sites</p> Signup and view all the answers

    In which location do substances frequently accumulate within the cell?

    <p>Lysosomes</p> Signup and view all the answers

    Which type of cell injury results from the cells producing an abnormal substance?

    <p>Transient accumulation</p> Signup and view all the answers

    What causes the accumulation of a normal endogenous substance when the rate of metabolism is inadequate to remove it?

    <p>Inadequate rate of metabolism</p> Signup and view all the answers

    Study Notes

    Cell Injury Types and Recovery

    • Reversible cell injury: Occurs when cells can recover and reestablish health upon removal of the stressor.
    • Irreversible cell injury: Results in permanent damage; cells cannot regain function after the removal of physiological stress and pathological stimuli.

    Causes of Cell Injury

    • Common causes of cell injury: Include reduced oxygen supply, immune reactions, infections, and toxicity.
    • Not a cause of cell injury: Undefined in the provided questions; requires clarification.
    • Reduction of oxygen supply: Major factor leading to cellular injury is hypoxia, which severely limits aerobic metabolism.
    • Infectious agents: Various forms, such as viruses, bacteria, fungi, and protozoa, can induce cell injury through pathogen-induced damage.

    Immune Reaction Mechanisms

    • Immune-mediated cell injury: Involves antibodies or T-cells targeting exogenous (non-self) antigens, primarily seen in autoimmune diseases or reactions.
    • Type of immune reaction: Can cause injury through mechanisms like hypersensitivity or allergic reactions.

    Cellular Accumulation

    • Normal cellular constituents: Examples include lipids or proteins that can accumulate in excess due to metabolic issues or pathological conditions.
    • Primary causes of accumulation: Abnormal exogenous substances often result from environmental toxins or infectious agents, affecting cellular functions.
    • Common accumulation sites: Substances frequently accumulate within the cytoplasm or organelles of the cell.

    Metabolic Implications

    • Normal endogenous substance accumulation: Happens when metabolic processes are inadequate to eliminate substances, leading to conditions like fatty liver disease.
    • Abnormal substance production: Cells may generate excess normal substances due to metabolic disorders, contributing to pathological states.

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    Description

    Test your knowledge on cell injury, necrosis, and apoptosis with this quiz. Explore the different types of cell injury and understand the processes of reversible and irreversible cell damage.

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