18 Questions
What initiates the cell cycle in a cell?
Growth factors
Which phase of the cell cycle follows the S-phase and precedes mitosis?
G2
What is the main goal of mitosis in a cell?
Even distribution of genomic material
In which phase of the cell cycle do all the chromosomes become visible?
M-phase
Why is it crucial for cells to stick to the order of events in the cell cycle?
To prevent 4n cells after 2 rounds of replication
What ensures that cells maintain the order of events in the cell cycle?
Mechanism in place
What is the consequence of a plant alkaloid binding to tubulin dimers during cell division?
Continued disassembly
Which type of cancer is commonly associated with high expression of estrogen receptors?
Breast cancer
In the context of anti-cancer drugs, what is the mechanism of action of tamoxifen?
Binds to estrogen receptors
How do leuprolide and goserelin contribute to cancer treatment?
Cease testosterone production
What is the significance of using anti-cancer drugs with different modes of action in combination?
Enhances treatment effectiveness
Why is it important for microtubules not to remain attached to chromosomes after cell division is complete?
Ensures accurate chromosome segregation
What is the function of CDK (cyclin-dependent kinase) in the cell cycle?
Blocks replication of DNA during S-phase
What is the role of CKI (inhibitor protein) in the cell cycle?
Binds to and inhibits CDK function
Which step ensures the activation of CDK in the cell cycle?
Cyclin phosphorylation
What happens if there is an error in the cell cycle process?
Binding of CKI to CDK
How is cyclin CDK complex activity regulated at the start of the cell cycle?
Presence of phosphates blocking CDK activity
What distinguishes the cell cycle regulation mechanism in humans from simple organisms?
Presence of multiple cyclins and CDKs in humans
Test your knowledge on cell division and the regulation process which determines when cells should divide. Learn about the internal and external factors that influence cell division decisions.
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