Cell Differentiation + Epigenetics + Phenotype
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Questions and Answers

How do stem cells become specialized?

Through differential gene expression, where different genes in their DNA become active and get expressed.

What triggers the activation of certain genes in a stem cell?

A stimulus, such as a chemical signal, triggers the activation of certain genes.

What is the role of mRNA in the process of cell specialization?

mRNA is translated on ribosomes to produce proteins.

What is the role of transcription factors in controlling gene expression?

<p>Transcription factors control the expression of genes by either stimulating or inhibiting transcription.</p> Signup and view all the answers

What is the difference between activators and repressors?

<p>Activators stimulate gene expression by increasing the rate of transcription, while repressors inhibit gene expression by decreasing the rate of transcription.</p> Signup and view all the answers

What is an operon, and how does it function in prokaryotes?

<p>An operon is a section of DNA that includes a cluster of structural genes that are transcribed together, and it functions by binding to transcription factors that either stimulate or inhibit transcription.</p> Signup and view all the answers

How do transcription factors bind to DNA in eukaryotes?

<p>Transcription factors bind to specific DNA sites near the start of target genes.</p> Signup and view all the answers

What is the result of cell specialization?

<p>The cell becomes irreversibly specialized, with permanent modifications to its structure and function.</p> Signup and view all the answers

What is the significance of differential gene expression in cell specialization?

<p>Differential gene expression allows different cells to specialize and acquire unique structures and functions.</p> Signup and view all the answers

How do transcription factors control the rate of transcription?

<p>Transcription factors control the rate of transcription by either increasing or decreasing the rate of transcription.</p> Signup and view all the answers

What is the function of the promoter region in gene expression?

<p>It is a DNA sequence that RNA polymerase initially binds to, enabling a gene to be transcribed.</p> Signup and view all the answers

What is the role of the lac repressor in the lac operon?

<p>It binds to the operator site, preventing RNA polymerase from binding to the promoter region and blocking transcription.</p> Signup and view all the answers

What is the effect of lactose on the lac operon?

<p>It binds to the lac repressor, changing its shape and preventing it from binding to the operator site, allowing RNA polymerase to bind to the promoter region and initiate transcription.</p> Signup and view all the answers

What is epigenetics, and how does it differ from genetics?

<p>Epigenetics is the study of heritable changes in gene function that do not involve a change in the base sequence of DNA. It involves the switching-on and switching-off of genes without altering the genetic code.</p> Signup and view all the answers

How does DNA methylation affect gene expression?

<p>It adds a methyl group to cytosine bases, preventing RNA polymerase from binding to the promoter region and suppressing gene expression.</p> Signup and view all the answers

What is the effect of acetylation on histones?

<p>It adds an acetyl group to histone proteins, making the DNA less tightly wrapped around the histones and allowing RNA polymerase to bind to the promoter region and initiate transcription.</p> Signup and view all the answers

How does deacetylation affect gene expression?

<p>It removes acetyl groups from histone proteins, making the chromatin more condensed and preventing RNA polymerase from binding to the promoter region, resulting in gene repression.</p> Signup and view all the answers

What is the significance of epigenetic changes in cell division?

<p>Epigenetic changes can be passed on after cell division, affecting the expression of genes in daughter cells.</p> Signup and view all the answers

What is the relationship between epigenetic modifications and cancer?

<p>Epigenetic modifications, such as acetylation, can lead to the activation of inappropriate genes, increasing the risk of cancer.</p> Signup and view all the answers

What is the difference between methylation and acetylation in terms of gene expression?

<p>Methylation typically represses gene expression, while acetylation typically activates gene expression.</p> Signup and view all the answers

What is the significance of epigenetic changes being passed on to daughter cells?

<p>Certain genes that are activated or deactivated in the original cell will also be activated or deactivated in the daughter cells.</p> Signup and view all the answers

What is the purpose of removing epigenetic marks during gamete production?

<p>To remove epigenetic marks, such as methylation and acetylation, allowing for a reset of gene expression in the zygote.</p> Signup and view all the answers

What is the difference between continuous and discontinuous variation in phenotype?

<p>Continuous variation shows a range of values, while discontinuous variation shows distinct categories with no in-between variants.</p> Signup and view all the answers

How does environmental influence affect the expression of polygenic traits?

<p>Environmental factors can influence the expression of polygenic traits, such as height and skin color, by interacting with genetic factors.</p> Signup and view all the answers

What is the difference between monogenic and polygenic inheritance?

<p>Monogenic inheritance is influenced by one gene, showing discontinuous variation, while polygenic inheritance is influenced by multiple genes, showing continuous variation.</p> Signup and view all the answers

How can epigenetic changes occur in response to environmental factors?

<p>Epigenetic changes can occur in response to environmental factors, allowing daughter cells to be better adapted to the changed environment.</p> Signup and view all the answers

What is the role of acetylation of histones in gene expression?

<p>Acetylation of histones activates genes, allowing for gene expression.</p> Signup and view all the answers

What is the significance of meiosis in removing epigenetic marks?

<p>Meiosis removes most acetylation and methylation, allowing for a reset of gene expression in the zygote.</p> Signup and view all the answers

How can cancer affect the cell cycle?

<p>Cancer can disrupt the cell cycle by bypassing critical checkpoints, allowing damaged DNA to be replicated and abnormal cells to divide.</p> Signup and view all the answers

What is the significance of studying non-differentiated embryonic stem cells?

<p>Non-differentiated embryonic stem cells are totipotent and have not yet activated or deactivated genes, making them useful for research.</p> Signup and view all the answers

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