Podcast
Questions and Answers
What inhibits anaphase if even a single kinetochore is unattached or lacks tension?
What inhibits anaphase if even a single kinetochore is unattached or lacks tension?
- Activation of APC/CCdc20
- Mps1 kinase phosphorylation of Knl1 (correct)
- Dephosphorylation of Knl1 by Protein phosphatase 1
- Silencing of the spindle position checkpoint pathway
Which complex is formed by Mad2, BubR1, Bub3, and Cdc20 in the spindle assembly checkpoint pathway?
Which complex is formed by Mad2, BubR1, Bub3, and Cdc20 in the spindle assembly checkpoint pathway?
- Mitotic Checkpoint Complex (MCC) (correct)
- KnL1 complex
- Mad1-Mad2 complex
- APC/CCdc20
Which protein dephosphorylates Knl1, eliminating checkpoint protein binding sites at kinetochores?
Which protein dephosphorylates Knl1, eliminating checkpoint protein binding sites at kinetochores?
- Mad2
- Protein phosphatase 1 (correct)
- BubR1
- Cdc20
What is the role of active Mad2 in the spindle assembly checkpoint pathway?
What is the role of active Mad2 in the spindle assembly checkpoint pathway?
What is the function of p31comet in the spindle assembly checkpoint pathway?
What is the function of p31comet in the spindle assembly checkpoint pathway?
What triggers the activation of the Mad1-Mad2 complex in the spindle assembly checkpoint pathway?
What triggers the activation of the Mad1-Mad2 complex in the spindle assembly checkpoint pathway?
Which kinase phosphorylates Knl1 when kinetochores are unattached to microtubules?
Which kinase phosphorylates Knl1 when kinetochores are unattached to microtubules?
Which proteins form the spindle position checkpoint pathway?
Which proteins form the spindle position checkpoint pathway?
What happens to APC/CCdc20 when Mad2 is active?
What happens to APC/CCdc20 when Mad2 is active?
What is the consequence of Knl1 phosphorylation by the Mps1 kinase when kinetochores are not attached to microtubules?
What is the consequence of Knl1 phosphorylation by the Mps1 kinase when kinetochores are not attached to microtubules?
What role does the Mad1-Mad2 complex play in the spindle assembly checkpoint pathway?
What role does the Mad1-Mad2 complex play in the spindle assembly checkpoint pathway?
What is the function of the Mitotic Checkpoint Complex (MCC) in the spindle assembly checkpoint pathway?
What is the function of the Mitotic Checkpoint Complex (MCC) in the spindle assembly checkpoint pathway?
Which protein is responsible for dephosphorylating Knl1 to eliminate checkpoint protein binding sites at kinetochores?
Which protein is responsible for dephosphorylating Knl1 to eliminate checkpoint protein binding sites at kinetochores?
What triggers the activation of APC/CCdc20 in the spindle assembly checkpoint pathway?
What triggers the activation of APC/CCdc20 in the spindle assembly checkpoint pathway?
Which kinase is involved in phosphorylating Knl1 when kinetochores are not attached to microtubules?
Which kinase is involved in phosphorylating Knl1 when kinetochores are not attached to microtubules?
In the spindle assembly checkpoint pathway, what is the role of p31comet?
In the spindle assembly checkpoint pathway, what is the role of p31comet?
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