Cancer
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Questions and Answers

It is a phase in cancer cell cycle wherein the cell enlarges and synthesizes proteins to prepare for cell division.

  • S phase
  • Gap 2 phase
  • M phase
  • Gap 1 phase (correct)

It is the regression of a cell to an immature or undifferentiated cell type

  • Metaplasia
  • Dysplasia
  • Anaplasia (correct)
  • Neoplasia

A process by which normal cells are transformed into cancer cells

  • Oncology
  • Carcinogenesis/Oncogenesis (correct)
  • Oncologist
  • Carcinogen

It determines the size of the tumor and the existence of local invasion and distant metastasis

<p>Staging (A)</p> Signup and view all the answers

It is a protein immune suppressor

<p>P53 (B)</p> Signup and view all the answers

Uncontrolled growth and spread of abnormal cells

<p>Cancer (C)</p> Signup and view all the answers

loss of DNA control over differentiation occuring in response to adverse conditions

<p>Dysplasia (C)</p> Signup and view all the answers

What phase in cancer cell cycle wherein the cell makes important proteins to be used in cell division

<p>Gap 2 phase (A)</p> Signup and view all the answers

TNM stands for?

<p>Tumor, nodes, Metastasis (D)</p> Signup and view all the answers

A tumor was shown to posses cells that were moderately differentiated. This is considered a?

<p>Grade 2 (B)</p> Signup and view all the answers

All Forms of Cancer use the same grading system?

<p>False (B)</p> Signup and view all the answers

What is the meaning of cancer in situ?

<p>The tumor is found in original place and has not spread from its original location (A)</p> Signup and view all the answers

The category "N" in the TNM system gives detail about?

<p>Node (C)</p> Signup and view all the answers

What TNM classification has the poorest prognosis

<p>T4N3M1 (D)</p> Signup and view all the answers

Which stage of cancer is called metastic cancer and means the cancer has spread to other parts of the body beyond where the cancer is started?

<p>Stage 4 (B)</p> Signup and view all the answers

What TNM classification below best describes this finding: Very large tumor with 1 regional lymph node involvement, and spread to two regional organs?

<p>T4N1M1 (C)</p> Signup and view all the answers

The TNM staging system for cancer be used to help stage what type of cancer?

<p>Colon Cancer (B)</p> Signup and view all the answers

it begins in the bone, cartilage, fat, muscle, connective or supportive tissue

<p>Sarcoma (A)</p> Signup and view all the answers

Begins in the tissue of brain and spinal cord

<p>CNS (C)</p> Signup and view all the answers

It is a permanent change in DNA nucleotide sequence, arise spontaneously from a mutagen

<p>Mutations (A)</p> Signup and view all the answers

What are the 3 stages of Carcinogenesis?

<p>Initiation, promotion, progression (A)</p> Signup and view all the answers

What is the primary cause of death in patient with cancer?

<p>Infection (D)</p> Signup and view all the answers

The most common site for cancer caused by smoking

<p>Bladder (B)</p> Signup and view all the answers

The nurse is teaching the patient ways to help prevent them from getting cancer. Which patient response indicates the need for more teaching?

<p>&quot;I do not need to limit my alcohol intake at all.&quot; (D)</p> Signup and view all the answers

A nurse is caring for patient undergoing chemotherapy. Which diet would the nurse expect the patient to prescribed?

<p>high protein and high calorie (B)</p> Signup and view all the answers

You are teaching a group of nursing students about the characteristics of cancer cell growth. Which of the following statements by a nursing student indicates the need for further teaching?

<p>&quot;Cancer cells will only produce two cells at the time of mitosis.&quot; (C)</p> Signup and view all the answers

Which stage in the development of cancer is characterized by the reversible proliferation of altered cells?

<p>Promotion (B)</p> Signup and view all the answers

Which of the following patients is experiencing one of the seven warning signs of cancer?

<p>A 67-year-old female who has a sore that does not heal. (D)</p> Signup and view all the answers

What is the effect of chemotherapy on cells?

<p>It eliminates or reduces the number of cancer cells in the primary tumor and metastatic tumor sites. (A)</p> Signup and view all the answers

A nurse is caring for a patient who is receiving intravesical bladder chemotherapy. Which adverse effect should the nurse monitor for?

<p>Hematuria (B)</p> Signup and view all the answers

Which immune response plays a dominant role in resisting tumor growth?

<p>Cytotoxic T cells (C)</p> Signup and view all the answers

A 76-year old patient who is undergoing cancer treatments comes into the emergency room with complains of weakness, muscle cramps, diarrhea, nausea, and vomiting. The patient's labs reveal hyperuricemia, hyperphosphatemia, hyperkalemia, and hypocalcemia. Which oncologic emergency is this patient most likely experiencing?

<p>Tumor Lysis Syndrome (B)</p> Signup and view all the answers

The nurse should become familiar with the use of which mnemonic for his/her own knowledge and for patient teaching of warning signs associated with cancer?

<p>CAUTION (D)</p> Signup and view all the answers

Which of the following cancers would not be clinically staged?

<p>Leukemia (A)</p> Signup and view all the answers

Which of the following statements is NOT true about benign and malignant neoplasms?

<p>Benign neoplasms are poorly differentiated, while malignant neoplasms are normally differentiated. (B)</p> Signup and view all the answers

Flashcards

Carcinogenesis

The process by which normal cells transform into cancerous cells.

Mutation

A change in the DNA sequence. It can happen spontaneously or be caused by mutagens.

Progression

The stage where cancer cells grow and spread aggressively.

Initiation

The initial stage of carcinogenesis, where normal cells start to become cancerous.

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Promotion

The stage in carcinogenesis where the transformed cells grow and multiply.

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Metastasis

The spread of cancer cells from the primary tumor to other parts of the body.

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De-differentiation

The process of a cell reverting to a more immature and undifferentiated state.

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G1 phase

The cell cycle phase where a cell increases in size and synthesizes proteins to prepare for division.

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Cancer in situ

A tumor that has not spread to other parts of the body.

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TNM System

The size of the primary tumor, lymph node involvement, and metastasis.

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Undifferentiated cells

Cancer cells that are not well-differentiated; they lose their specialized characteristics.

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N category

This category in the TNM system indicates lymph node involvement.

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Stage IV cancer

This stage of cancer is metastatic, meaning it has spread to other parts of the body.

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M1 classification

The TNM classification with the worst prognosis, indicating cancer has spread to distant sites.

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Sarcoma

A cancer that starts in the bone, cartilage, fat, muscle, or connective tissue.

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Central nervous system cancer

A cancer that starts in the brain or spinal cord.

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Cell-mediated immunity

The immune response that is primarily involved in fighting tumor growth.

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Tumor lysis syndrome

A condition that occurs when cancer cells break down rapidly, releasing large amounts of waste products into the blood.

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CAUTION

A mnemonic for cancer warning signs, meaning change in bowel or bladder habits, a sore that doesn't heal, unusual bleeding or discharge, thickening or lump, indigestion or difficulty swallowing, obvious change in a wart or mole, nagging cough or hoarseness.

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Benign neoplasm

A type of neoplasm that doesn't invade surrounding tissue.

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Malignant neoplasm

A type of neoplasm that invades surrounding tissue and spreads to other parts of the body.

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Chemotherapy diet

A high-calorie, high-protein diet is recommended for patients undergoing chemotherapy.

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Effect of chemotherapy

Chemotherapy kills cancer cells by targeting rapidly dividing cells.

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Adverse effect of intravesical chemotherapy

A common side effect of intravesical bladder chemotherapy is bladder irritation.

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Cancer prevention teaching

If a patient doesn't understand the importance of cancer prevention, they may need more teaching about the topic.

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Brain cancer

A type of cancer that is not staged because it's located inside the brain, making it difficult to measure.

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Lung

The most common site for cancer caused by smoking.

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Study Notes

Cancer Cell Cycle

  • G1 phase: cell enlarges and synthesizes proteins to prepare for cell division
  • De-differentiation: regression of a cell to an immature or undifferentiated cell type

Cancer Development

  • Carcinogenesis: process by which normal cells are transformed into cancer cells
  • Loss of DNA control over differentiation: occurs in response to adverse conditions

Cancer Characteristics

  • Uncontrolled growth and spread of abnormal cells
  • Loss of differentiation: characterizes cancer cells

Tumor Grading and Staging

  • TNM stands for Tumor, Node, Metastasis
  • TNM system determines the size of the tumor and the existence of local invasion and distant metastasis
  • Cancer in situ: cancer that remains at the site of origin
  • Category "N" in the TNM system: gives detail about nodal involvement
  • TNM classification with the poorest prognosis: M1 (distant metastasis)
  • Stage IV cancer: called metastatic cancer and means the cancer has spread to other parts of the body beyond where the cancer started

Cancer Types

  • Cancer that begins in the bone, cartilage, fat, muscle, connective or supportive tissue: sarcoma
  • Cancer that begins in the tissue of brain and spinal cord: central nervous system cancer

Carcinogenesis

  • Mutation: a permanent change in DNA nucleotide sequence, arises spontaneously from a mutagen
  • 3 stages of Carcinogenesis: initiation, promotion, and progression

Cancer Complications

  • Primary cause of death in patients with cancer: metastasis
  • Most common site for cancer caused by smoking: lung

Cancer Prevention and Treatment

  • Nurse teaching patient ways to prevent cancer: patient response indicates need for more teaching if they don't understand the importance of prevention
  • Diet for patient undergoing chemotherapy: high-calorie, high-protein diet
  • Effect of chemotherapy on cells: kills cancer cells
  • Adverse effect of intravesical bladder chemotherapy: bladder irritation

Cancer and the Immune System

  • Immune response that plays a dominant role in resisting tumor growth: cell-mediated immunity

Oncologic Emergencies

  • Oncologic emergency: tumor lysis syndrome (characterized by hyperuricemia, hyperphosphatemia, hyperkalemia, and hypocalcemia)

Cancer Warning Signs

  • Mnemonic for cancer warning signs: CAUTION
  • Cancer that would not be clinically staged: brain cancer
  • Benign and malignant neoplasms: benign neoplasms do not invade surrounding tissue, whereas malignant neoplasms do

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