Podcast
Questions and Answers
What is the function of CDC25 in the cell cycle?
What is the function of CDC25 in the cell cycle?
- Phosphorylates CDK1
- Inhibits MPF
- De-phosphorylates CDK1 (correct)
- Activates MPF
What role does Maturation-Promoting Factor (MPF) play in the cell cycle?
What role does Maturation-Promoting Factor (MPF) play in the cell cycle?
- Regulates protein synthesis in the G1 phase
- Inhibits cell division in the G2 phase
- Stimulates both mitosis and meiosis (correct)
- Triggers DNA replication in the S phase
Which subunit of Maturation-Promoting Factor (MPF) uses ATP to add phosphate groups to specific serine and threonine residues on target proteins?
Which subunit of Maturation-Promoting Factor (MPF) uses ATP to add phosphate groups to specific serine and threonine residues on target proteins?
- Ubiquitin ligase
- Cyclin
- CDK1 (correct)
- Wee1
Which term is often used to describe MPF due to its precise phosphorylation of target proteins during mitosis?
Which term is often used to describe MPF due to its precise phosphorylation of target proteins during mitosis?
How do mutations in tumor suppressor genes impact cell cycle control?
How do mutations in tumor suppressor genes impact cell cycle control?
What is the function of the inhibitory enzyme Wee1 in the cell cycle?
What is the function of the inhibitory enzyme Wee1 in the cell cycle?
Which specific sequence in cyclins leads to their destruction when recognized by the ubiquitin ligase enzyme?
Which specific sequence in cyclins leads to their destruction when recognized by the ubiquitin ligase enzyme?
What is the role of proto-oncogenes in cell proliferation?
What is the role of proto-oncogenes in cell proliferation?
What is the primary function of Cyclin-Dependent Kinase 1 (CDK1) in the cell cycle?
What is the primary function of Cyclin-Dependent Kinase 1 (CDK1) in the cell cycle?
Which gene product is associated with monitoring DNA damage as a tumor suppressor gene?
Which gene product is associated with monitoring DNA damage as a tumor suppressor gene?
What happens when Maturation-Promoting Factor (MPF) is recognized by ubiquitin ligase?
What happens when Maturation-Promoting Factor (MPF) is recognized by ubiquitin ligase?
What happens when CDK1 binds to cyclin B in the cell cycle?
What happens when CDK1 binds to cyclin B in the cell cycle?
What is the main function of Maturation-Promoting Factor (MPF) in the cell cycle?
What is the main function of Maturation-Promoting Factor (MPF) in the cell cycle?
Which protein components make up Maturation-Promoting Factor (MPF)?
Which protein components make up Maturation-Promoting Factor (MPF)?
What is another name for Cyclin-dependent kinase 1 (Cdk1)?
What is another name for Cyclin-dependent kinase 1 (Cdk1)?
Which process is triggered by the activation of MPF in the cell cycle?
Which process is triggered by the activation of MPF in the cell cycle?
What can result from the loss of cell cycle control?
What can result from the loss of cell cycle control?
What role do Tumor Suppressor Genes play in cell growth?
What role do Tumor Suppressor Genes play in cell growth?
