Cell Cycle Checkpoints and G0 Phase
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Questions and Answers

What is one of the factors a cell assesses at the G1 checkpoint before deciding to divide?

  • Presence of neighboring cells that have already divided
  • Nutritional reserves and energy availability (correct)
  • Availability of hormones from the bloodstream
  • Type of surrounding tissue

What happens to a cell that does not receive the necessary cues at the G1 checkpoint?

  • It undergoes apoptosis, or programmed cell death
  • It continues through the cell cycle unpredictably
  • It enters a resting state known as G0 phase (correct)
  • It immediately divides into two daughter cells

Which of the following statements about the G0 phase is true?

  • Cells in G0 are actively preparing to divide
  • All cells that enter G0 remain there permanently
  • G0 phase is the same as mitosis
  • Some cells in G0 can return to the cell cycle if conditions improve (correct)

Which factor is NOT assessed by a cell at the G1 checkpoint?

<p>Cellular age (A)</p> Signup and view all the answers

Why is the G1 checkpoint critical for cellular division?

<p>It checks for sufficient energy and resources to ensure successful division (D)</p> Signup and view all the answers

Flashcards

G1 Checkpoint

A critical point in the cell cycle where a cell assesses internal and external conditions before division.

Cell Size

Crucial factor for cell division; a cell needs to be large enough.

Nutrients

Essential energy for cell division; enough nutrients are needed for cell growth.

Molecular Signals

Growth factors from neighbors which signal whether the cell should divide.

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DNA Integrity

Cell checks DNA for damage before division.

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G0 Phase

A resting state if a cell doesn’t get enough cues at G1 checkpoint.

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Cell Cycle

Series of events leading to cell division

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Study Notes

G1 Checkpoint

  • Cell checks internal and external factors before division.
  • Size: Cell must be large enough to divide.
  • Nutrients: Cell needs sufficient energy and nutrients.
  • Molecular signals: Positive cues (growth factors) are assessed.
  • DNA integrity: Cell checks for DNA damage.

G0 Phase

  • If conditions aren't met at G1, the cell exits the cell cycle.
  • Cell enters a resting state called G0.
  • Some cells permanently stay in G0.
  • Other cells can re-enter the cell cycle if conditions improve.

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Description

This quiz focuses on the G1 checkpoint and G0 phase of the cell cycle. Learn about the requirements for cell division, including size, nutrients, molecular signals, and DNA integrity. Explore what happens when conditions aren't met and how cells can enter a resting state.

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