Cell Connections Quiz - Epithelial and Cardiac Tissue
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Questions and Answers

Which of the following cell connections primarily serves as a barrier to the movement of molecules between epithelial cells?

  • Adhesion Belts
  • Tight Junctions (correct)
  • Desmosomes
  • Gap Junctions
  • Which type of cell connection is most likely to be found in areas subjected to significant mechanical stress, like the skin?

  • Hemidesmosomes
  • Tight Junctions
  • Desmosomes (correct)
  • Adhesion Belts
  • What is the primary function of hemidesmosomes?

  • Creating a permeability barrier between cells.
  • Facilitating intercellular communication.
  • Anchoring epithelial cells to the basement membrane. (correct)
  • Connecting epithelial cells to one another.
  • Which of the following is NOT a function of gap junctions?

    <p>Providing structural support to tissues. (C)</p> Signup and view all the answers

    Which of the following cell connections is directly involved in coordinating the contraction of cardiac muscle cells by allowing electrical signals to pass between them?

    <p>Gap Junctions (D)</p> Signup and view all the answers

    Which type of cell connection provides additional strength to the tight junctions, helping to anchor epithelial cells to each other and prevent the passage of materials between cells?

    <p>Adhesion Belts (B)</p> Signup and view all the answers

    What type of cell connection is primarily responsible for the formation of intercalated disks, which are found between cardiac muscle cells?

    <p>Desmosomes (A), Gap Junctions (C)</p> Signup and view all the answers

    Which type of cell connection is likely to be found in tissues that require a high degree of cell-to-cell communication, such as smooth muscle, where coordinated contractions are essential?

    <p>Gap Junctions (A)</p> Signup and view all the answers

    Which type of cartilage has the greatest ability to withstand compression and tension forces?

    <p>Fibrocartilage (B)</p> Signup and view all the answers

    What is the primary function of perichondrium in cartilage growth?

    <p>All of the above (D)</p> Signup and view all the answers

    Which of the following correctly describes the difference between spongy bone and compact bone?

    <p>Spongy bone has a lattice-like structure with spaces, while compact bone appears more solid and dense. (B)</p> Signup and view all the answers

    Which component provides the rigidity and strength to bone?

    <p>Hydroxyapatite crystals (B)</p> Signup and view all the answers

    Which type of cartilage is most likely to be found in the external ear?

    <p>Elastic Cartilage (A)</p> Signup and view all the answers

    What is the unique feature of blood that distinguishes it from other connective tissues?

    <p>Blood has a fluid matrix. (D)</p> Signup and view all the answers

    Which of the following pairs of tissues are both found in the knee joint?

    <p>Hyaline Cartilage and Fibrocartilage (C)</p> Signup and view all the answers

    What is the primary role of osteocytes in bone tissue?

    <p>Maintenance of bone tissue and communication with other cells (C)</p> Signup and view all the answers

    What is the key factor that determines the color of thicker areas of the stratum corneum?

    <p>The thicker stratum corneum absorbs more light, resulting in a yellowish hue. (C)</p> Signup and view all the answers

    A patient presents with a scaly red patch on their skin that persists. What type of skin cancer could this potentially be?

    <p>Squamous cell carcinoma (B)</p> Signup and view all the answers

    Why are fair-skinned individuals at a greater risk of developing skin cancer compared to darker-skinned individuals?

    <p>Fair skin has less melanin, providing less protection from UV radiation. (B)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of basal cell carcinoma?

    <p>It can appear as a wartlike growth. (B)</p> Signup and view all the answers

    What is the primary mechanism by which UV radiation contributes to skin cancer development?

    <p>UV radiation damages the DNA of epidermal cells, causing mutations that can lead to cancer. (D)</p> Signup and view all the answers

    What is the significance of the statement 'the deeper, the bluer' in relation to skin color?

    <p>It describes the appearance of blood vessels in the dermis, which appear bluer at greater depths. (A)</p> Signup and view all the answers

    Which of the following factors is NOT directly linked to an increased risk of developing skin cancer?

    <p>Having a family history of skin cancer. (D)</p> Signup and view all the answers

    Why is melanoma considered the most deadly type of skin cancer?

    <p>It spreads rapidly and is often diagnosed in advanced stages. (B)</p> Signup and view all the answers

    What role does the hair papilla have in hair structure?

    <p>It provides blood supply and nourishment. (C)</p> Signup and view all the answers

    Which part of the hair structure primarily consists of hard keratin?

    <p>Cortex (A)</p> Signup and view all the answers

    What happens to the internal epithelial root sheath during hair removal?

    <p>It detaches and is visible as a white bulb. (B)</p> Signup and view all the answers

    What triggers the transition from growth stage to resting stage in hair growth?

    <p>Shortening of the hair follicle. (B)</p> Signup and view all the answers

    How does vellus hair differ from other types of hair?

    <p>It is fine and short. (D)</p> Signup and view all the answers

    Which layer of the hair structure contains cells that overlap like shingles on a roof?

    <p>Cuticle (A)</p> Signup and view all the answers

    What is the primary cause of permanent hair loss, such as pattern baldness?

    <p>Genetic predisposition. (A)</p> Signup and view all the answers

    Which component of hair structure is primarily responsible for hair production?

    <p>Matrix (A)</p> Signup and view all the answers

    What is primarily responsible for the structural strength of the dermis?

    <p>Collagen fibers (D)</p> Signup and view all the answers

    Which factor does NOT contribute to variations in skin color?

    <p>Environmental temperature (A)</p> Signup and view all the answers

    When melanomas invade the dermis, what major consequence can occur?

    <p>Difficult treatment options (C)</p> Signup and view all the answers

    Which of the following is a key feature of the ABCDE Rule for identifying melanomas?

    <p>Asymmetry (A)</p> Signup and view all the answers

    What type of sensory nerve endings are involved in detecting deep pressure?

    <p>Pacinian corpuscles (D)</p> Signup and view all the answers

    Which stratum of the epidermis is primarily involved in the formation of new cells through mitosis?

    <p>Stratum basale (C)</p> Signup and view all the answers

    What type of skin has hair follicles, thick dermis, and is more resistant to abrasion?

    <p>Thick skin (C)</p> Signup and view all the answers

    Which component of the skin contributes most to the barrier against water loss?

    <p>Keratinized cells (C)</p> Signup and view all the answers

    Which of the following correctly describes the modification process of cholecalciferol?

    <p>It is first modified in the liver before reaching the kidneys. (D)</p> Signup and view all the answers

    What is the primary substance excreted through sweat?

    <p>Urea (D)</p> Signup and view all the answers

    In what way does calcitriol function within the body?

    <p>Stimulates the uptake of calcium and phosphate in the small intestine. (A)</p> Signup and view all the answers

    What is the precursory role of 7-dehydrocholesterol in vitamin D synthesis?

    <p>It converts to cholecalciferol when exposed to UV light. (A)</p> Signup and view all the answers

    Which statement about the excretion process in the body is true?

    <p>The kidneys primarily excrete most of the body's waste products. (B)</p> Signup and view all the answers

    What is a common result of a deficiency in vitamin D among certain populations?

    <p>Decreased calcium and phosphate uptake. (B)</p> Signup and view all the answers

    Which types of injury does the term 'burn' encompass?

    <p>Injuries caused by chemicals, electricity, and friction. (B)</p> Signup and view all the answers

    Where is cholecalciferol produced in the body before being modified into active vitamin D?

    <p>In the skin upon UV exposure. (B)</p> Signup and view all the answers

    Flashcards

    Melanoma Appearance

    Melanomas can appear skin-colored, pink, red, or purple when melanin production stops.

    Melanoma Development

    40 percent of melanomas develop from existing moles.

    Epidermis Treatment Success

    Melanoma treatment is almost always successful if confined to the epidermis.

    ABCDE Rule for Melanoma

    The ABCDE rule helps identify melanoma: Asymmetry, Border irregularity, Diameter > 6mm, Evolving.

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    Epidermis Strata

    The epidermis has five strata; new cells are formed in the stratum basale. Outer strata contain dead cells.

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    Keratinozation Benefits

    Keratinozation strengthens the epidermis and prevents water loss through tough cell formation.

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    Cells Producing Melanin

    Melanocytes produce melanin, which protects the skin from UV radiation.

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    Skin Color Influences

    Carotene, blood flow, and O2 content impact skin color, along with melanin levels influenced by genetics and sun exposure.

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    Vellus Hair

    Fine, short hair found on the body.

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    Hair Structure

    The composition of hair including shaft, root, and bulb.

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    Medulla

    The central axis of hair consisting of soft keratin.

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    Cortex

    The bulk of hair that contains hard keratin.

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    Cuticle

    The outer layer of hair with overlapping cells.

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    Hair Follicle

    The skin structure from which hair grows, includes several layers.

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    Hair Growth Stages

    Cyclic phases of hair including growth and resting stages.

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    Alopecia Areata

    Spot baldness, commonly an autoimmune response.

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    Skin Cancer

    Most common cancer type caused by UV radiation damaging DNA in skin cells.

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    UV Radiation Effects

    UV radiation causes mutations in DNA, which can lead to skin cancer if not repaired.

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    Risk Factors for Skin Cancer

    Fair skin, aging, and prolonged sun exposure increase skin cancer risk.

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    Types of Skin Cancer

    Includes basal cell carcinoma, squamous cell carcinoma, and melanoma, varying in severity.

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    Basal Cell Carcinoma

    Most common skin cancer, appears as open sores or shiny bumps, mostly curable.

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    Squamous Cell Carcinoma

    Second most common skin cancer affecting the stratum spinosum, may bleed or appear as warts.

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    Melanoma

    Least common but most deadly skin cancer, arises from melanocytes, often black or brown.

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    Hyaline Cartilage

    A type of cartilage that forms most of the skeleton in embryos and aids in growth.

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    Perichondrium

    Dense irregular connective tissue that surrounds cartilage and can form chondroblasts.

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    Fibrocartilage

    A type of cartilage with thick collagen fiber bundles, providing toughness and slight compressibility.

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    Elastic Cartilage

    Cartilage containing many elastic fibers, providing rigidity with elasticity.

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    Bone

    A hard connective tissue composed of living cells and mineralized matrix.

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    Osteocytes

    Bone cells located in lacunae within the mineralized matrix of bone.

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    Spongy Bone

    Bone that has spaces between plates (trabeculae), resembling a sponge.

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    Fluid Connective Tissue

    A connective tissue with a liquid matrix, allowing cells to move freely, exemplified by blood.

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    Cholecalciferol

    A form of vitamin D produced from 7-dehydrocholesterol upon UV exposure.

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    Calcitriol

    The active form of vitamin D, regulates calcium and phosphate levels.

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    Vitamin D synthesis process

    Involves conversion of 7-dehydrocholesterol to cholecalciferol via UV light.

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    Function of calcitriol

    Stimulates absorption of calcium and phosphate in the intestine.

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    Sources of Vitamin D

    Includes dairy, liver, egg yolks, and supplements.

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    Excretion in the body

    Removal of waste products, including urea, uric acid, and ammonia.

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    Sweat and excretion

    Sweat excretes water, salts, and minor waste; kidneys handle most waste.

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    Causes of burns

    Injuries caused by cold, friction, chemicals, electricity, or radiation.

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    Desmosomes

    Disk-shaped regions of cell membrane that provide strong adhesion between cells, especially in stressed areas.

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    Hemidesmosomes

    Half of a desmosome that anchors epithelial cells to the basement membrane, preventing tissue movement.

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    Tight Junction

    Connections that hold cells tightly together, creating a barrier to molecular movement.

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    Adhesion Belt

    Structures found below tight junctions that anchor epithelial cells for additional strength.

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    Gap Junctions

    Protein channels that allow intercellular communication by letting ions and small molecules pass between cells.

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    Coordination of Muscle

    Function of gap junctions that enables electrical signals to pass between cardiac and smooth muscle cells.

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    Epithelial Glands

    Specialized secretory organs composed of epithelium supported by connective tissue.

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    Basement Membrane

    A thin layer that anchors epithelial tissue to underlying connective tissue.

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    Study Notes

    Tissues Lectures

    • Homeostasis is the balance of materials and energy needed to keep an individual alive, maintained through cells.
    • Organs are formed when two or more tissues combine.
    • Tissue is the fabric of the body, defined as woven.
    • The type of tissue determines its function.
    • Four primary tissue types: nervous, muscle, epithelial, and connective tissues. Nervous tissue provides control and communication, muscle tissue provides movement, epithelial tissues line body cavities and organs and provide covering and protection, and connective tissues provide support.
    • Histology is the study of tissues.
    • Carmine is a red dye used to stain tissue and identify different cell structures.
    • Nervous tissue forms the central nervous system and peripheral nerves, functions to sense stimuli and send electrical impulses throughout the body.
    • Neurons are the specialized building blocks of the nervous system, responsible for generating and conducting electrochemical nerve impulses.
    • Glial cells support, insulate, protect, and connect to blood vessels.
    • Nervous tissue is composed of cell bodies (life support for neurons), nucleus, mitochondria, DNA, dendrites (collect signals from other cells), and axons (carry messages to other neurons, muscles, and glands).
    • The nervous system regulates and controls the body's functions, including the brain and spinal cord (Central Nervous System) and nerves (Peripheral Nervous System).
    • Muscle tissues contract and move.

    Three Types of Muscle Tissues

    • Skeletal muscle tissue: long, multinucleated, parallel cells with striations, voluntary movement, location throughout the body.
    • Cardiac muscle tissue: branched, uninucleated cells with striations and intercalated disks, involuntary movement, location in the heart.
    • Smooth muscle tissue: short, tapered cells without striations, involuntary movement, location in blood vessels and hollow organs.

    Epithelial Tissues

    • Two types: proper (covers and lines the outer and inner body) and glandular (forms glands and secretes hormones and other substances).
    • Avascular; meaning they do not have blood vessels. They rely on the connective tissues for nutrients.
    • Classified by shape of cells, and the number of layers they form.

    Basic Shapes

    • Squamous cells: flattened, fast absorption and diffusion, thin membranes.
    • Cuboidal cells: spherical nuclei, cube shaped, absorb nutrients and produce secretions like sweat
    • Columnar cells: elliptical nuclei, column shape, absorb nutrients and produce secretions.

    Types of Layering

    • Simple epithelium: one layer
    • Stratified epithelium: many layers
    • Pseudostratified epithelium: appears layered but is not, most have cilia.

    Classification of Epithelial Tissues

    • First name: number of layers
    • Last name: shape of cell

    Connective Tissues

    • Function of connective tissue (most abundant tissue in the body): binding and supporting, insulating, protecting, storing energy, and transporting substances.
    • Types of connective tissues: proper, cartilage, bone, and blood (connective).
    • Characteristics of connective tissue: developed from mesenchyme, a loose embryonic tissue; varying degrees of vascularity (and blood flow); extracellular matrix as a non-living material.
    • Extracellular Matrix components: Ground substance (watery, flexible, and unstructured material that fills space between cells to protect from surrounding) and protein fibers (collagen, elastic, and reticular)
    • Types of connective tissue fibers: Collagen fibers (strongest, most abundant, provide support and structure), Elastic fibers (long thin, provide elasticity and flexibility, found in lungs and arteries), Reticular fibers (short, thin fibers form a network, support organs and tissues like spleen)
    • Different types of connective proper tissues: Loose (e.g., areolar and adipose), and Dense tissues (e.g., regular, irregular, and elastic).

    Types of Connective Tissue (continued)

    • Different types of connective tissue: Reticular tissue (supports lymph nodes, spleen and bone marrow)
    • Different types of connective tissue: Dense ( regular- tendons, ligaments, irregular-dermis of skin , elastic -walls of elastic arteries and large arteries)
    • Different types of connective tissue: Cartilage (hyaline- end of bones, ribs, nose, embryonic skeleton, fibrocartilage- intervertebral discs, pubic symphysis, elastic-external ear, epiglottis)
    • Different types of connective tissue: Bone (spongy, compact, bone marrow)
    • Different types of connective tissue: Blood (fluid, plasma, erythrocytes [red blood cells], leukocytes [white blood cells], and platelets)

    Embryonic Tissues

    • Hypoblast and epiblast layers develop into three germ layers: endoderm, mesoderm, and ectoderm.
    • The germ layers develop into the various tissues and organs of the body.

    Epithelial Tissue

    • Mostly cells, little matrix
    • Forms coverings and linings
    • Has an exposed surface that is in contact with either the environment or the inner space of an organ cavity.
    • Epithelial cells have apical surfaces (free), basal surface (attached) and lateral surfaces (between cells, for cell connection).
    • Basement membrane: noncellular material secreted by the epithelial cells, anchors epithelial cells, and supports cells.
    • Different types of epithelial tissue: classified by the number of layers and the shape of the surface or apical cells.

    Epithelial Tissues (continued)

    • Simple squamous epithelium: lining of blood vessels, heart, lymphatic tissues, lungs' alveoli.
    • Simple cuboidal epithelium: glands, kidney tubules, choroid plexus.
    • Simple columnar epithelium: stomach lining, some parts of the intestines.
    • Pseudostratified columnar epithelium: lining of trachea, nasal cavity, auditory tubes, pharynx, bronchi.
    • Stratified squamous epithelium: skin, mouth, esophagus (non-keratinized), skin, cornea (keratinized).
    • Stratified cuboidal epithelium: sweat duct lining, parts of ovarian follicles.
    • Stratified columnar epithelium: mammary gland duct.
    • Transitional epithelium: lining of urinary bladder, ureters, superior urethra.

    Functional Characteristics of Simple Epithelium

    • Lists of common locations and functions for each type of simple epithelium.

    Functional Characteristics of Stratified Epithelium

    • Stratified squamous epithelium: skin, mouth, esophagus, vagina
    • Stratified cuboidal epithelium: ducts of sweat and mammary glands
    • Stratified columnar epithelium: portion of urethra, ocular conjunctiva
    • Transitional epithelium: urinary bladder, ureters and superior urethra

    Cell Connections

    • Tight junctions (seals cells together, create an impermeable barrier.
    • Adhesion belts (hold cells together; anchor to cytoskeleton)
    • Gap junctions (formed from communicating channels; cells to communicate.)
    • Desmosomes (hold cells together; provide structural support)
    • Hemidesmosomes (attach cells to basement membrane, prevention of movement of the tissue).

    Glands

    • Glands are specialized secretory organs composed of epithelium and connective tissue.
    • Two types of glands: endocrine (no ducts, hormones released directly into blood stream ), and exocrine glands (ducts, secretions released onto surface).
    • Unicellular (single cell like goblet cells) and multicellular glands (compound). Glands are generally composed of a duct system and secretory portion or cells.
    • Modes of secretion: merocrine (exocytosis- most common), apocrine (portion of the cell pinched off with the secretion, mammary glands/ earwax), holocrine (entire cell breaks down to become secretion, sebaceous glands ).
    • Classifications based on duct system (simple-unbranched, compound-branched) and secretory portion (tubular or acinar -sac-like- for example, goblet cells in small intestines)

    Physiology of the Integumentary System

    • Protection from abrasion, microbes and UV radiation
    • Regulation of body temperature
    • Sensation via specialized receptors
    • Excretion of waste products and production of vitamin D.

    Muscle Tissue

    • Skeletal muscle: voluntary movement, striated, many nuclei.
    • Cardiac muscles: involuntary movement, striated and has single nuclei.
    • Smooth muscles: involuntary movement, not striated and has single nuclei.

    Nervous Tissue

    • Produces electrical signals to conduct impulses.
    • Neurons are the main components of nervous tissue
    • Neurons are composed of cell body, dendrites and axon.
    • Glia: supporting cells which nourish, protect and insulate neurons

    Tissue Membranes

    • Types: mucous (lines cavities open to exterior, secrete mucus), serous (lines closed cavities, serous fluid), and synovial (lines freely movable joints, produces synovial fluid)

    Tissue Damage and Inflammation

    • Body's reaction to injury or infection.
    • Characterized by redness, heat, swelling, pain, and disturbed function.
    • Chemical mediators: histamine, kinins, prostaglandins, leukotrienes.
    • Cellular response.
    • Process of repair: regeneration (replacement with the same cells), and replacement (scar tissue).

    Tissue Repair

    • Cells that regenerate (labile cells, unstable cells)
    • Cells that do not regenerate (permanent cells)
    • Types of wound healing: primary and secondary.

    Skin Repair

    • Primary union (edges close together, minimal scarring)
    • Secondary union (edges not close together, scar tissue is greater)

    Skin Cancer

    • The most common type of cancer is from epithelial tissue;
    • Types: basal cell carcinoma (most common, stratum basale), squamous cell carcinoma (stratum spinosum), and melanoma (melanocytes, most deadly).

    Skin: Additional Characteristics

    • Skin thickness variations (thick- palms, thin- rest of the body).
    • Skin colors due to pigments (melanin, carotene).
    • Accessory structures of the skin (hair, nails, and glands).

    Other Accessory Skin Structures

    • Hair
    • Nail:
    • Glands (sebaceous and sweat)
    • Hair color and type
    • Sensory functions of skin
    • Skin structure/layers (epidermis, dermis)
    • Subcutaneous tissue

    Other Body Systems

    • How they interact during injury (musculo-skeletal, nervous, lymph etc.) Additional characteristics of skin

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    Description

    Test your knowledge on different types of cell connections and their functions in epithelial and cardiac tissues. This quiz covers topics such as tight junctions, gap junctions, and hemidesmosomes, along with their roles in cellular communication and mechanical stress resistance. Perfect for students studying cell biology or related fields.

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