Podcast
Questions and Answers
What are the possible genotypes of the parents of a child with phenylketonuria (PKU)?
What are the possible genotypes of the parents of a child with phenylketonuria (PKU)?
- Heterozygous (correct)
- Homozygous for normal and recessive for PKU (correct)
- Homozygous dominant for normal phenotype
- Homozygous recessive for PKU
Which process contributes to genetic variation during meiosis?
Which process contributes to genetic variation during meiosis?
- Independent assortment of chromosomes (correct)
- Cytokinesis in somatic cells
- Mitosis
- Replication of DNA in S phase
How does a nucleus in G2 differ from a nucleus in G1?
How does a nucleus in G2 differ from a nucleus in G1?
- G2 has less DNA compared to G1
- G2 is not involved in protein synthesis like G1
- G1 undergoes DNA replication that does not occur in G2
- G2 contains twice the amount of DNA as G1 (correct)
What is the number of chromosomes in each gamete of a chicken with 78 chromosomes?
What is the number of chromosomes in each gamete of a chicken with 78 chromosomes?
In the signal transduction pathway, what is the first step when a receptor binds a signal?
In the signal transduction pathway, what is the first step when a receptor binds a signal?
What is the primary purpose of cell division in multicellular organisms?
What is the primary purpose of cell division in multicellular organisms?
During which phase of interphase does DNA replication occur?
During which phase of interphase does DNA replication occur?
What is the role of cell-cycle checkpoints in controlling cell division?
What is the role of cell-cycle checkpoints in controlling cell division?
What is a cleavage furrow and how is it formed during cytokinesis in animal cells?
What is a cleavage furrow and how is it formed during cytokinesis in animal cells?
Which structure is essential for correct chromosome movement during mitosis?
Which structure is essential for correct chromosome movement during mitosis?
What characterizes the difference between homologs and sister chromatids?
What characterizes the difference between homologs and sister chromatids?
What is the significance of apoptosis in cellular development?
What is the significance of apoptosis in cellular development?
What event characterizes the S phase of the cell cycle?
What event characterizes the S phase of the cell cycle?
What does a homozygous dominant genotype indicate?
What does a homozygous dominant genotype indicate?
In a test cross, what is the individual being tested crossed with?
In a test cross, what is the individual being tested crossed with?
What is the expected phenotypic ratio in the F2 generation of a monohybrid cross?
What is the expected phenotypic ratio in the F2 generation of a monohybrid cross?
How does Mendel's law of independent assortment relate to dihybrid crosses?
How does Mendel's law of independent assortment relate to dihybrid crosses?
Which of the following is an example of a human aneuploidy?
Which of the following is an example of a human aneuploidy?
Which term describes a cross between two organisms that are heterozygous for a single trait?
Which term describes a cross between two organisms that are heterozygous for a single trait?
What genetic condition is characterized by the presence of an extra X chromosome in males?
What genetic condition is characterized by the presence of an extra X chromosome in males?
What does the chromosomal theory of inheritance state?
What does the chromosomal theory of inheritance state?
What percentage chance does a son have of inheriting a disorder caused by an X-linked recessive allele if his mother is affected?
What percentage chance does a son have of inheriting a disorder caused by an X-linked recessive allele if his mother is affected?
During which stage of mitosis do chromosomes line up at the equator of the cell?
During which stage of mitosis do chromosomes line up at the equator of the cell?
The multiplication rule of probability is used to calculate what kind of genetic outcomes?
The multiplication rule of probability is used to calculate what kind of genetic outcomes?
In pedigree analysis, what do filled shapes typically represent?
In pedigree analysis, what do filled shapes typically represent?
What does '3-parent babies' refer to?
What does '3-parent babies' refer to?
Which genotype combination could lead to two X chromosomes inherited from both parents?
Which genotype combination could lead to two X chromosomes inherited from both parents?
What illustrates the concept of multifactorial traits in genetics?
What illustrates the concept of multifactorial traits in genetics?
How many different gametes can a genotype AaBbCCDdEE produce through independent assortment?
How many different gametes can a genotype AaBbCCDdEE produce through independent assortment?
What selective advantage does the sickle-cell allele provide in malaria-prone areas?
What selective advantage does the sickle-cell allele provide in malaria-prone areas?
Which receptor is most likely associated with the action of vitamin D, a lipid-soluble molecule?
Which receptor is most likely associated with the action of vitamin D, a lipid-soluble molecule?
Why is Drosophila melanogaster commonly used in genetic research?
Why is Drosophila melanogaster commonly used in genetic research?
What is the role of the SRY gene in sex determination?
What is the role of the SRY gene in sex determination?
Which of the following best describes monosomic and trisomic conditions?
Which of the following best describes monosomic and trisomic conditions?
What is X-inactivation and what effect does it have on females?
What is X-inactivation and what effect does it have on females?
What characterizes codominance in the context of sickle-cell disease?
What characterizes codominance in the context of sickle-cell disease?
Which of the following describes the term 'carrier' in genetics?
Which of the following describes the term 'carrier' in genetics?
What distinguishes codominance from incomplete dominance?
What distinguishes codominance from incomplete dominance?
Which of the following techniques is used for fetal testing during pregnancy?
Which of the following techniques is used for fetal testing during pregnancy?
In a monohybrid cross of two heterozygous pea plants (Aa), what is the expected phenotypic ratio of the offspring?
In a monohybrid cross of two heterozygous pea plants (Aa), what is the expected phenotypic ratio of the offspring?
Which of the following best defines pleiotropy?
Which of the following best defines pleiotropy?
What is the expected genotypic ratio for a dihybrid cross of two heterozygous plants (AaBb)?
What is the expected genotypic ratio for a dihybrid cross of two heterozygous plants (AaBb)?
Which statement is true about polygenic inheritance?
Which statement is true about polygenic inheritance?
In the ABO blood group system, which of the following is true about the alleles involved?
In the ABO blood group system, which of the following is true about the alleles involved?
Flashcards
Cell signal termination
Cell signal termination
The process of stopping signal transduction after a cell has processed a signal to avoid prolonged or unwanted responses.
Apoptosis
Apoptosis
Programmed cell death, a crucial process in organism development and maintenance.
Cell division in unicellular organisms
Cell division in unicellular organisms
Cell division enables reproduction and ensures the continuation of the species in single-celled organisms.
Cell division in multicellular organisms
Cell division in multicellular organisms
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Genome
Genome
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Chromosome
Chromosome
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Gene
Gene
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Chromatin
Chromatin
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Chromosome condensation
Chromosome condensation
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Sister chromatids
Sister chromatids
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Centromere
Centromere
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Gametes
Gametes
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Somatic cells
Somatic cells
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Interphase
Interphase
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M phase
M phase
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G1 phase
G1 phase
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S phase
S phase
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G2 phase
G2 phase
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Mitosis
Mitosis
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Cytokinesis
Cytokinesis
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Cell cycle checkpoints
Cell cycle checkpoints
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G0 phase
G0 phase
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Allele
Allele
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Dominant Allele
Dominant Allele
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Recessive Allele
Recessive Allele
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Punnett Square
Punnett Square
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Homozygote
Homozygote
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Homozygous Dominant
Homozygous Dominant
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Homozygous Recessive
Homozygous Recessive
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Heterozygote
Heterozygote
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Heterozygous
Heterozygous
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Phenotype
Phenotype
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Genotype
Genotype
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Monohybrid
Monohybrid
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Monohybrid cross
Monohybrid cross
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Dihybrid
Dihybrid
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Dihybrid cross
Dihybrid cross
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Test cross
Test cross
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Law of Segregation
Law of Segregation
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Law of Independent Assortment
Law of Independent Assortment
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Aneuploidy examples
Aneuploidy examples
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How are mitochondrial genes inherited?
How are mitochondrial genes inherited?
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Mitochondrial disease example
Mitochondrial disease example
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"3-parent babies"
"3-parent babies"
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Blood type A x B possible offspring
Blood type A x B possible offspring
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Polygenic inheritance skin color
Polygenic inheritance skin color
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X-linked recessive disorder
X-linked recessive disorder
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XX inheritance and genetic condition
XX inheritance and genetic condition
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Mitosis stage: chromosomes line up
Mitosis stage: chromosomes line up
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Gamete production from independent assortment
Gamete production from independent assortment
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Chromosome composition
Chromosome composition
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Cell membrane receptors
Cell membrane receptors
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Vitamin D receptor location
Vitamin D receptor location
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Mendel's cross order
Mendel's cross order
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Recessive Allele Disorder
Recessive Allele Disorder
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Dominant Allele Disorder
Dominant Allele Disorder
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Carrier
Carrier
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Carrier Testing
Carrier Testing
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Fetal Testing
Fetal Testing
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Amniocentesis
Amniocentesis
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Chorionic Villus Sampling (CVS)
Chorionic Villus Sampling (CVS)
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Newborn Screening
Newborn Screening
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Incomplete Dominance
Incomplete Dominance
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Codominance
Codominance
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Multiple Alleles
Multiple Alleles
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Pleiotropy
Pleiotropy
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Epistasis
Epistasis
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Polygenic Inheritance
Polygenic Inheritance
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Monohybrid Cross (Aa x Aa)
Monohybrid Cross (Aa x Aa)
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Dihybrid Cross
Dihybrid Cross
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Independent Assortment
Independent Assortment
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PKU parents' genotypes
PKU parents' genotypes
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Biofilm response
Biofilm response
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G2 vs. G1 nucleus
G2 vs. G1 nucleus
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Meiosis genetic variation
Meiosis genetic variation
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Plant cytokinesis
Plant cytokinesis
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Chicken gamete chromosomes
Chicken gamete chromosomes
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Chicken offspring chromosomes
Chicken offspring chromosomes
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Signal transduction pathway order
Signal transduction pathway order
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Human autosomes
Human autosomes
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Metaphase I vs. Mitosis arrangement
Metaphase I vs. Mitosis arrangement
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Differently shaded chromosomes
Differently shaded chromosomes
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Nature and nurture (genetics)
Nature and nurture (genetics)
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Multifactorial trait
Multifactorial trait
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Sickle-cell allele (recessive, incompletely dominant, codominant)
Sickle-cell allele (recessive, incompletely dominant, codominant)
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Sickle-cell allele advantage (malaria)
Sickle-cell allele advantage (malaria)
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Drosophila melanogaster (fruit flies)
Drosophila melanogaster (fruit flies)
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Wild-type phenotype
Wild-type phenotype
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Mutant phenotype
Mutant phenotype
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Morgan's key findings (fruit flies)
Morgan's key findings (fruit flies)
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Sex determination in mammals
Sex determination in mammals
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SRY gene
SRY gene
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Sex-linked gene
Sex-linked gene
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X-linked gene
X-linked gene
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Y-linked gene
Y-linked gene
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WNT4 gene
WNT4 gene
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X-inactivation
X-inactivation
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Barr body
Barr body
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Mosaic
Mosaic
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Nondisjunction (meiosis)
Nondisjunction (meiosis)
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Aneuploidy
Aneuploidy
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Monosomic
Monosomic
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Trisomic
Trisomic
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Nondisjunction (mitosis)
Nondisjunction (mitosis)
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Chromosomal structural alterations
Chromosomal structural alterations
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Study Notes
Cell Communication - Practice Questions
- Two general reasons cells use signaling mechanisms are to respond to external stimuli and maintain homeostasis.
- Cell signaling is an ancient process, dating back to very early evolutionary stages.
- Quorum sensing in bacteria involves the accumulation of signaling molecules to coordinate group behavior, crucial for virulence and biofilm formation.
- In yeast, quorum sensing differs by relying on faster, localized communication mechanisms.
- The cell's ability to respond to a signal molecule is dependent on the receptor.
- The three stages of cell signaling are Reception, Transduction, and Response.
- Receptor proteins bind to ligands, often located on the cell surface.
- Cell surface receptors include receptor tyrosine kinases, ion-channel receptors, and G protein-coupled receptors.
- Intracellular receptors, often for steroid hormones, bind to ligands directly inside the cell
- Hydrophobic, lipid-soluble ligands typically bind to intracellular receptors.
- Different types of ligands bind to intracellular receptors, such as peptide hormones.
- Both hydrophobic and hydrophilic ligands can bind to certain receptors.
Cell Cycle and Mitosis
- Cell division's purpose in unicellular organisms is reproduction. In multicellular organisms, it's for growth, repair, and development.
- Chromosomes are organized into chromatin and contain genes.
- Chromatin condenses into chromatids, linked via a centromere.
- Gametes are sex cells (sperm/egg). Somatic cells are non-sex cells.
- Homologous chromosomes are paired chromosomes. Sister chromatids are identical copies.
- Interphase involves cell growth and DNA replication (G1, S, G2 phases).
- M phase (Mitosis) is the process of cell division
- Mitosis involves prophase, metaphase, anaphase, and telophase
- Cytokinesis is the division of the cytoplasm and organelles.
- Differences in Cytokinesis in animal cells involve a cleavage furrow. In plant cells, a cell plate forms.
Cell Cycle Control and Cancer
- Cell-cycle checkpoints regulate the progression through the cell cycle, ensuring proper DNA replication and repair. They identify and correct genetic damage.
- Malfunction at checkpoints can lead to uncontrolled cell division, contributing to cancer development
- Factors influencing whether a cell enters G0 phase include growth factors, cell density, and nutrients.
- G0 is a non-dividing phase; cells can re-enter the cell cycle later.
Meiosis and Sexual Reproduction
- Asexual reproduction results in genetically identical offspring.
- Sexual reproduction leads to genetically diverse offspring.
- Genetic variation through meiosis is crucial for adapting to changing environments.
- Meiosis involves two divisions creating four haploid cells from a diploid cell.
- Key genetic terms include allele, phenotype, genotype, loci, genome, and Punnett squares.
- Different processes in meiosis lead to variation (i.e. independent assortment, crossing over).
- Review steps of fertilization and how ploidy changes.
Complex Inheritance Patterns and Human Genetics
- Human genetics is impacted by factors like incomplete dominance, codominance, multiple alleles, pleiotropy, and epistasis.
- Multiple alleles affect phenotypes in a complex way.
- Sex-linked alleles affect traits differently in males and females.
- Monohybrid and dihybrid crosses predict genetic outcomes.
- Pedigree analysis traces inheritance patterns in families.
- Diseases (like sickle cell) are sometimes associated with multiple recessive and dominant factors.
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