Cell Communication and Signaling Unit 4
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Questions and Answers

What is the process that human cells use to communicate with each other?

Cell communication

What is the name for direct contact between cells, where their cytoplasms are directly connected?

Juxtacrine signaling

What are specialized intercellular connections found in certain animal cell-types that directly connect the cytoplasm of two cells?

Gap junctions

What is the name of the communication that happens over short distances, where a cell sends out signals to nearby cells?

<p>Paracrine signaling</p> Signup and view all the answers

What is the name of the communication that occurs when a cell sends chemical messages to itself?

<p>Autocrine signaling</p> Signup and view all the answers

What is the name of the communication that occurs when the cells communicate with each other by sending ligands through the bloodstream?

<p>Endocrine signaling</p> Signup and view all the answers

What is the name of the process where the instructions of our DNA are converted into a product?

<p>Gene expression</p> Signup and view all the answers

What is the process by which the body maintains a balanced concentration of glucose in the bloodstream?

<p>Blood sugar level regulation</p> Signup and view all the answers

What are the two main types of diabetes?

<p>Type 1 and Type 2</p> Signup and view all the answers

What is the name for the entire cell division process that is regulated by the Cdk-Cyclin complex?

<p>Cell cycle</p> Signup and view all the answers

What are the three main phases of interphase in the cell cycle?

<p>G1, S, and G2</p> Signup and view all the answers

What is the part of the cell cycle when the nucleus of the cell is divided?

<p>Mitosis</p> Signup and view all the answers

What is the process called that occurs after mitosis where the cytoplasm is divided in two?

<p>Cytokinesis</p> Signup and view all the answers

What is the name of the part of the cell cycle where a cell never divides, and it can re-enter the cell cycle when it gets the appropriate signals?

<p>G0 Phase</p> Signup and view all the answers

What is the name for the process where a cell ceases to function and ultimately dies?

<p>Cell death</p> Signup and view all the answers

What is the process called that occurs when a less specialized cell becomes a more specialized cell type?

<p>Cell differentiation</p> Signup and view all the answers

What is the name of the protein that is considered the toolbox of the cell, and it plays a crucial role in preventing cancer by regulating the cell cycle and initiating apoptosis in response to DNA damage?

<p>p53</p> Signup and view all the answers

What are the control mechanisms in the cell cycle that ensure each stage is completed accurately before proceeding to the next?

<p>Cell cycle checkpoints</p> Signup and view all the answers

What is the process called that is a normal and controlled process within multicellular organisms that maintains the balance of cells within an organism by eliminating old, unnecessary, or damaged cells?

<p>Apoptosis</p> Signup and view all the answers

What is the simple sugar (monosaccharide) that serves as the main source of energy for cells in living organisms?

<p>Glucose</p> Signup and view all the answers

What serves as the primary form of energy storage in animals and fungi, and it is similar to starch, but has more extensive branching?

<p>Glycogen</p> Signup and view all the answers

What is a hormone produced by the pancreas that regulates the amount of glucose in the blood and allows cells to take in glucose from the bloodstream and use it as energy?

<p>Insulin</p> Signup and view all the answers

What is a molecule that binds to another (usually larger) molecule, acting as the signal molecule in cell communication?

<p>Ligand</p> Signup and view all the answers

What is the process by which cells build proteins, involving two main stages: transcription (where DNA is converted into RNA) and translation (where RNA is used to produce proteins)?

<p>Protein synthesis</p> Signup and view all the answers

What is a system of stimulus and response that is correlated to population density, and it is often used by bacteria to coordinate gene expression based on the local population density?

<p>Quorum sensing</p> Signup and view all the answers

What are series of chemical reactions within a cell that are triggered by signals at its surface, leading to changes inside the cell, such as activation of genes or alterations in cellular metabolism?

<p>Signal transduction pathways</p> Signup and view all the answers

What are man-made organic chemicals that were extensively used in numerous industrial applications but are now banned due to their environmental persistence and potential health risks?

<p>Polychlorinated Biphenyls (PCBs)</p> Signup and view all the answers

What are large biomolecules that perform a vast array of functions within organisms, and they function as structural components, enzymes, and carriers for other molecules?

<p>Proteins</p> Signup and view all the answers

What is a molecule found on the surface of cells that binds to specific substances, triggering a specific response in the cell?

<p>Receptor protein</p> Signup and view all the answers

What are the types of genes that are protective genes and they regulate cell growth. When these genes mutate, they may fail to control cell growth effectively, potentially leading to cancerous tumors.

<p>Tumor suppressor genes</p> Signup and view all the answers

What refers to the damage or disruption of the structure and function of neurons, often due to exposure to natural or artificial toxic substances?

<p>Neurotoxic effects</p> Signup and view all the answers

What are substances that reduce the activity of enzymes, slowing down or even stopping certain reactions in the body?

<p>Inhibitors</p> Signup and view all the answers

What are the specialized types of cells found in the pancreas that produce important enzymes and hormones, such as insulin and glucagon, which regulate blood sugar levels.

<p>Pancreas cells</p> Signup and view all the answers

What are the microscopic channels that traverse the cell walls of plant cells and some algal cells, enabling transport and communication between them?

<p>Plasmodesmata</p> Signup and view all the answers

What is the process by which replicated chromosomes are separated into two new nuclei, resulting in genetically identical cells with equal distribution of genetic material?

<p>Mitosis</p> Signup and view all the answers

What is a stage in both mitosis and meiosis where all chromosomes align at the center (equator) of the cell, before being separated into two new cells?

<p>Metaphase</p> Signup and view all the answers

What is a small dense spherical structure in the nucleus of a cell, and it is involved in protein synthesis, and it produces and assembles ribosome components?

<p>Nucleoli</p> Signup and view all the answers

What is the first stage of mitosis, during which chromosomes condense and become visible under light microscopy, and the nuclear envelope breaks down?

<p>Prophase</p> Signup and view all the answers

What is a phase in the cell cycle, and it is part of the cell cycle where DNA replication occurs. It ensures that both new cells will have complete sets of chromosomes?

<p>S phase</p> Signup and view all the answers

What is a plate that develops at midline of dividing plant cell during cytokinesis, eventually becoming the cell wall for each of the two daughter cells?

<p>Cell plate</p> Signup and view all the answers

What is the process during cell division where the cytoplasm divides into two daughter cells after mitosis or meiosis?

<p>Cytokinesis</p> Signup and view all the answers

What are cylindrical structures found in most eukaryotic cells, and they are involved in cellular division and the formation of spindle fibers that separate chromosomes during mitosis?

<p>Centrioles</p> Signup and view all the answers

What is an organelle found in most eukaryotic cells, and it is responsible for pulling apart sister chromatids during cell division?

<p>Centrosome</p> Signup and view all the answers

What is a complex of DNA and proteins that forms chromosomes within the nucleus of eukaryotic cells, and it condenses to form chromosomes during cell division and decondenses for gene expression?

<p>Chromatin</p> Signup and view all the answers

What is a shallow groove that forms in the cell membrane during cytoplasmic division in animal cells, and it is the first sign of cytokinesis during cell division?

<p>Cleavage furrow</p> Signup and view all the answers

What is a type of gene that allows organisms to respond to physical contact or pressure, playing a crucial role in the development and function of sensory cells?

<p>Touch-sensor gene</p> Signup and view all the answers

Study Notes

Introduction to Unit 4

  • The human body is composed of trillions of cells with diverse functions.
  • Cells operate in unison by communicating with each other for proper functioning.
  • Cells undergo a process, the cell cycle, to generate new cells.
  • Proper regulation of cell communication and the cell cycle is crucial for correct functioning. It's like a checklist with specific timing and coordination.

4.1 Cell Communication

  • Skills you'll gain: describing cell communication, differentiating signaling types, explaining signal reception, relating signaling to responses, and predicting impacts on functioning.

Mechanisms of Cell Signaling

  • Cells communicate in various ways, often using chemical signals (typically proteins).
  • Juxtacrine signaling: direct contact between adjacent cells via junctions (plasmodesmata in plants, gap junctions in animals).
  • Paracrine signaling: communication over short distances; cells send signals to nearby cells affecting their behaviors (e.g., muscle contraction, nerve signaling). Synaptic signaling is a specific example, involving a synapse (gap) and neurotransmitters.
  • Autocrine signaling: a cell sends a chemical message to itself (e.g., cancer cells).
  • Endocrine signaling: communication over longer distances; ligands (signal molecules) travel through the bloodstream to target cells in different parts of the body (e.g., insulin signaling).

4.3 Signal Transduction

  • Skills you gain include understanding: amplification of signals using phosphorylation cascades and second messengers, how transduction pathways impact cellular responses, the role of second messengers in signal transmission, and the correlation between signal variations and cellular responses.
  • Signal amplification and cellular responses: cells react and respond to environmental changes.

Signal Transduction Pathways

  • Gene expression: DNA instructions are converted into products (like proteins).
  • Signal transduction pathways influence gene expression by altering protein synthesis product quantities.
  • Signal transduction pathways impact other cellular functions (e.g. cell death, cell differentiation, shape changes, metabolism).

4.4 Changes in Signal Transduction Pathways

  • Skills: explain how mutations, drugs, and toxins affect signaling, linking signaling disruptions and diseases (e.g., cancer).
  • Impacts of disruptions: mutations can affect protein production and signal transduction impacting cell cycle regulation. This can lead to unregulated cell division and diseases, like cancer.
  • Feedback loops may compensate for signaling changes, influencing cellular function.
  • In the absence of these regulatory functions cells can have unlimited growth or fail to respond properly to checkpoints or signals necessary for proper cellular development.

4.6 Cell Cycle

  • Cell cycle stages: interphase (G1, S, and G2), mitosis, and cytokinesis.
  • Key functions and roles, includes DNA replication and division, growth, development, tissue repair.
  • Role of checkpoints: control mechanisms that ensure each stage is complete before proceeding.
  • Signals regulate cell cycle progression. This is very important because cell cycle disruptions can cause problems, like cancer.
  • G0 phase: cells that do not divide or are in a resting state.
  • Mitosis progression through prophase, metaphase, anaphase, telophase.
  • Cytokinesis—the division of cytoplasm
  • How plant and animal cells differ in cytokinesis.

4.7 Regulation of Cell Cycle

  • Skills: explaining how checkpoints control cell cycle progression preventing errors, describing protein regulation of cell division, relating cell cycle regulation to conditions like cancer, explaining the consequences of disrupted cell cycle regulation.
  • Cell Cycle Checkpoints: control mechanisms to ensure proper functioning (G1, G2, metaphase).
  • Mistakes in cell replication cause mutations. This is involved in development of abnormal and cancerous cells that can grow uncontrolled.
  • Cell cycle checkpoints halt the cycles until the previous steps are confirmed to have completed properly.
  • Understanding these processes is critical to maintaining cell and tissue health
  • Apoptosis-programmed cell death, crucial for balance within organisms. Prevents uncontrolled division/growth
  • Cellular factors and environmental factors affect signaling pathways and cell cycle regulation.

Apoptosis

  • Programmed cell death in multicellular organisms.
  • Maintaining balance within the organism; getting rid of old/unnecessary/damaged cells.
  • Apoptosis is triggered when certain cellular components are not in balance/ or are not functional leading to malfunction.
  • Without apoptosis harmful cell proliferation could result causing cancerous growths.

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Unit 4 PDF: Cell Communication

Description

Explore the essential mechanisms of cell communication in this quiz focused on Unit 4. Understand how cells operate and relate through various signaling types, and learn about the process of the cell cycle. Test your knowledge on the critical regulation of these functions for proper bodily operations.

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