Cell Biology Quiz on Membranes and Organsims
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Questions and Answers

What role does the glycocalyx play in cellular activity?

  • It facilitates the exchange of nutrients and waste between the cell and its environment.
  • It acts solely as a barrier to prevent substances from entering the cell.
  • It serves as a molecular identifier for the immune system to differentiate between healthy and diseased cells. (correct)
  • It allows for unrestricted movement of particles in and out of the cell.
  • Which of the following is NOT a function of the glycocalyx?

  • Immunity to infection by recognizing foreign organisms.
  • Protection of the plasma membrane from chemical injury.
  • Enhancement of nutrient absorption into the cell. (correct)
  • Defense against cancer through immune recognition.
  • How does the glycocalyx contribute to transplant compatibility?

  • By providing identification markers that the immune system uses to assess foreignness. (correct)
  • By promoting the growth of new cells in the donor site.
  • By creating an impermeable barrier to pathogens.
  • By enabling cells to absorb nutrients more efficiently.
  • What property of the plasma membrane allows certain substances to pass while restricting others?

    <p>Semipermeability of the plasma membrane. (D)</p> Signup and view all the answers

    What is the significance of membrane potential in a cell?

    <p>It refers to the difference in electric potential across the cell membrane. (B)</p> Signup and view all the answers

    Which statement accurately describes non-cellular organisms?

    <p>They exist as a protein coat or capsid outside of host cells. (B)</p> Signup and view all the answers

    What characterizes unicellular organisms that live in colonies?

    <p>Each individual cell must carry out all life processes to survive. (C)</p> Signup and view all the answers

    Which type of organisms are considered to have eukaryotic cells?

    <p>Yeasts. (A)</p> Signup and view all the answers

    What is the primary function of the endocrine and nervous systems in multicellular organisms?

    <p>To manage coordination among organ tissues. (B)</p> Signup and view all the answers

    Which statement correctly describes the hierarchy of living systems?

    <p>Each object is built from the basic units of the preceding level. (A)</p> Signup and view all the answers

    What is the primary reason that a cell must be an open system?

    <p>To facilitate the exchange of matter and energy (D)</p> Signup and view all the answers

    Which component allows cells to adapt to their environment?

    <p>Signaling pathways (B)</p> Signup and view all the answers

    Which of the following elements is classified as a macroelement necessary for cell survival?

    <p>Potassium (K) (C)</p> Signup and view all the answers

    What type of compounds are proteins, carbohydrates, lipids, and nucleic acids considered?

    <p>Organic compounds (C)</p> Signup and view all the answers

    Which of the following is NOT a similarity between eukaryotes and prokaryotes?

    <p>Both have a semi-permeable membrane (A)</p> Signup and view all the answers

    Which form of communication is primarily associated with cell signaling?

    <p>Chemical communication (A)</p> Signup and view all the answers

    What is the role of the semi-permeable membrane in a cell?

    <p>To regulate the flow of substances in and out of the cell (C)</p> Signup and view all the answers

    Which of the following is true regarding microelements in cells?

    <p>They play crucial roles in enzyme functions. (C)</p> Signup and view all the answers

    What role do membrane proteins play in transport within the cell membrane?

    <p>They act as gates or pumps using ATP. (B)</p> Signup and view all the answers

    Which of the following statements about membrane fluidity is true?

    <p>Cholesterol can both increase and decrease membrane fluidity. (A)</p> Signup and view all the answers

    What is one function of membrane compartments within eukaryotic cells?

    <p>They establish physical boundaries for biological processes. (D)</p> Signup and view all the answers

    How do glycolipids contribute to cell interaction?

    <p>They serve as ID tags recognized by other cells. (B)</p> Signup and view all the answers

    What is a characteristic of intramembrane domains of membrane proteins?

    <p>They have largely hydrophobic surfaces interacting with lipids. (C)</p> Signup and view all the answers

    What are the consequences of having unsaturated fatty acids in the membrane?

    <p>They create larger spaces between membrane phospholipids. (B)</p> Signup and view all the answers

    Which membrane protein function involves initiating a cellular response to external signals?

    <p>Receptors for signal transduction (A)</p> Signup and view all the answers

    How does the fluid-mosaic model describe the arrangement of cellular membranes?

    <p>The membrane includes cholesterol and proteins distributed throughout the phospholipid bilayer. (B)</p> Signup and view all the answers

    What is the primary function of G Protein-Coupled Receptors (GPCRs)?

    <p>Mediating responses to a variety of signaling molecules (B)</p> Signup and view all the answers

    What happens to receptor tyrosine kinases upon ligand binding?

    <p>They undergo dimerization leading to phosphorylation (C)</p> Signup and view all the answers

    What is the primary driving force behind osmosis?

    <p>Osmotic pressure (A)</p> Signup and view all the answers

    Which subunit of heterotrimeric G proteins is responsible for GTPase activity?

    <p>Alpha (D)</p> Signup and view all the answers

    How does ligand binding affect ligand-gated ion channels?

    <p>It opens or closes the channel (A)</p> Signup and view all the answers

    Which type of channel is regulated by specific ligand binding?

    <p>Ligand-gated channels (C)</p> Signup and view all the answers

    What describes an isotonic solution in relation to cytosol?

    <p>Equal solute concentration as cytosol (B)</p> Signup and view all the answers

    What is the role of adenylyl cyclase in signaling pathways?

    <p>To convert ATP to cAMP (D)</p> Signup and view all the answers

    What is a key characteristic of primary active transport?

    <p>Directly uses energy from ATP hydrolysis (B)</p> Signup and view all the answers

    What type of receptors are primarily responsible for mediating insulin signaling?

    <p>Receptor Tyrosine Kinases (B)</p> Signup and view all the answers

    Which of the following describes a hypertonic solution?

    <p>Higher solute concentration than the cytosol (B)</p> Signup and view all the answers

    Which of the following best describes the function of integrins?

    <p>To facilitate communication and adhesion between cells (C)</p> Signup and view all the answers

    How does secondary active transport differ from primary active transport?

    <p>Involves the transport of two different molecules (C)</p> Signup and view all the answers

    Which pathway does phospholipase C activate in response to thrombin signaling?

    <p>DAG and IP3 production (B)</p> Signup and view all the answers

    What is the primary function of vesicular transport?

    <p>Transport large particles and macromolecules (C)</p> Signup and view all the answers

    Which mechanism moves sodium ions out of the cell and potassium ions into the cell?

    <p>Sodium-potassium pump (B)</p> Signup and view all the answers

    Flashcards

    Virus Structure

    Viruses are composed of a nucleic acid (DNA or RNA) and a protein coat (capsid). Their structure can be helical, icosahedral, or complex.

    Viral Reproduction

    Viruses need a host cell to reproduce, as they cannot reproduce on their own. They hijack the host cell's mechanisms.

    Unicellular Organism Types

    Unicellular organisms include prokaryotes (bacteria, archaea) and eukaryotes (protozoa, algae, some fungi).

    Multicellular Organization

    Multicellular organisms (plants and animals) have cells with specialized functions, organized into tissues, organs, and systems.

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    Organ Systems Coordination

    The endocrine and nervous systems coordinate the function of organs and tissues in multicellular organisms.

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    Open System

    A system that exchanges matter and energy with its surroundings. Cells are open systems because they take in nutrients and release waste products.

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    Cell Membrane

    A semi-permeable barrier that controls what enters and exits the cell. It allows some molecules to pass through while blocking others.

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    Entropy

    A measure of disorder or randomness in a system. Cells need energy to maintain a stable level of order.

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    Genetic Material

    DNA, which contains all the information needed for a cell's structure and function. It's passed on during cell division.

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    Environmental Information

    Cells need information about their surroundings, such as the presence of nutrients or toxins, to adapt.

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    Signaling Pathways

    Communication networks within and between cells. They use signals like ions, proteins, and messengers to coordinate activities.

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    Eukaryotes vs. Prokaryotes

    Both types of cells have cell membranes, ribosomes, DNA, and cytoplasm. However, eukaryotes have a nucleus and other membrane-bound organelles, while prokaryotes do not.

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    Chemical Composition (Organic)

    Cells are mainly composed of organic compounds like proteins, carbohydrates, lipids, and nucleic acids. These molecules contain carbon, hydrogen, oxygen, nitrogen, phosphorus, and sulfur.

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    Intramembrane Domains

    Regions within the cell membrane formed by proteins with hydrophobic surfaces that interact with the hydrophobic tails of membrane lipids.

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    Membrane Protein Functions

    Membrane proteins perform various roles, including transport, enzymatic activity, signal transduction, intercellular joining, cell-cell recognition, and cytoskeleton/ECM attachment.

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    What does 'Fluid Mosaic' mean?

    The cell membrane isn't rigid, but rather a dynamic structure where phospholipids move freely and proteins are embedded like tiles in a mosaic.

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    What are the factors that affect membrane fluidity?

    Temperature, cholesterol levels, and fatty acid saturation influence membrane fluidity. Low temperatures make membranes more rigid, while cholesterol acts as a buffer, and unsaturated fatty acids increase fluidity.

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    What are membrane compartments?

    These are membrane-enclosed regions within eukaryotic cells, like mitochondria, endoplasmic reticulum, Golgi apparatus, and nucleus. They isolate specific processes.

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    Why are compartments important?

    They create boundaries for different biological processes, provide a large surface area for metabolic reactions, and allow for coordinated regulation of these processes.

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    What stabilizes membrane compartments?

    The cytoskeleton provides structure and stability to membrane compartments or organelles, ensuring their proper localization within the cell.

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    What does the plasma membrane do?

    The plasma membrane defines the cell boundary, separating the internal environment from the external environment.

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    Glycocalyx

    A thick outer covering of the plasma membrane, composed of carbohydrate chains attached to lipids and proteins. It acts as a protective layer and plays a crucial role in cell recognition and communication.

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    What does the glycocalyx help with?

    The glycocalyx plays a vital role in various cellular functions including: protecting the cell membrane, enabling the immune system to recognize foreign invaders, facilitating cell adhesion, and guiding embryonic development.

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    Semi-permeable membrane

    The cell membrane is selectively permeable, meaning it allows some substances to pass through while blocking others. This controlled passage ensures the cell maintains its internal environment and functions properly.

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    Membrane potential

    The difference in electrical charge between the inside and outside of a cell. This charge difference is essential for cellular processes like nerve impulses and muscle contractions.

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    What happens to the glycocalyx in cancer cells?

    The glycocalyx of cancer cells often changes, becoming more complex or altered. These changes can help the immune system recognize and target the cancerous cells.

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    Uniporter

    A type of membrane transport protein facilitating the movement of a single molecule across a membrane. It can be an ion channel or a carrier protein.

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    Passive membrane transport

    Movement of molecules across a cell membrane without requiring energy from the cell. Types include simple and facilitated diffusion, and osmosis.

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    Osmosis

    The movement of water across a semi-permeable membrane from a region of higher water concentration to a region of lower water concentration.

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    Tonicity

    The ability of a solution to change the shape (size) of a cell by influencing its water volume.

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    Isotonic Solution

    A solution with the same solute concentration as the cytosol of a cell. The cell maintains its normal shape and volume.

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    Active transport

    The movement of molecules across a cell membrane requiring energy expenditure, usually ATP.

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    Primary active transport

    Directly uses ATP hydrolysis to move molecules against their concentration gradient. Requires specific carrier proteins.

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    Secondary active transport

    Indirectly uses energy from an existing concentration gradient to transport molecules across the membrane, often couples another molecule's movement, like the sodium-glucose transporter.

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    Ligand-Gated Ion Channel

    A type of membrane receptor that acts as both a channel and a receptor. It controls the flow of ions across the cell membrane by opening or closing the channel when a specific ligand binds to it.

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    Enzyme-Linked Receptor

    A type of membrane receptor that has an intracellular enzyme activity, often a tyrosine kinase. It is activated by ligand binding, leading to phosphorylation of proteins and triggering signal transduction cascades.

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    G Protein-Coupled Receptor

    The largest family of cell surface receptors, involved in a wide range of signaling pathways. They associate with G proteins on the cytoplasmic side. Ligand binding activates the G protein, leading to intracellular signaling events.

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    Heterotrimeric G Protein

    A type of G protein composed of three subunits: alpha, beta, and gamma. The alpha subunit has GTPase activity, and its activation leads to signaling pathways.

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    Adenylyl Cyclase Pathway

    A signaling pathway activated by some G protein-coupled receptors. It involves the production of cyclic AMP (cAMP), a second messenger that regulates various cellular processes.

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    Phospholipase C Pathway

    A signaling pathway activated by some G protein-coupled receptors. It involves the production of diacylglycerol (DAG) and inositol triphosphate (IP3), both second messengers with different roles in signaling.

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    Cell Adhesion

    The process by which cells attach to each other and to the extracellular matrix (ECM). It is essential for tissue formation and function.

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    Integrins

    A family of cell adhesion molecules that link the cytoskeleton to the ECM. They play a role in cell signaling and migration.

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    Study Notes

    Biological Organization

    • A fundamental basis in medical sciences
    • Hierarchy of complex biological structures and systems define life
    • Each level of complexity builds on the units of the previous level

    Hierarchy of Living Systems

    • Organisms differ by their organizational complexity.
    • Non-cellular organisms: viruses
      • Simple structure: one molecule of nucleic acid (NA) and one type of protein
      • Complex structure: one molecule of NA, several types of proteins and other chemical compounds (mostly lipids)
      • Viruses rely on host cells for reproduction
    • Unicellular organisms
      • Prokaryotes (bacteria, archaea)
        • Simple cells, lacking membrane-bound organelles
        • Precursors to modern eukaryotes
      • Eukaryotes (protozoa, unicellular algae, fungi)
        • More complex cells with membrane-bound organelles
    • Multicellular organisms
      • Most animal and plant species
      • Cells with specific functions
      • Tissues formed by similar cells
      • Organs formed by combinations of tissues
      • Organ systems formed from combinations of organs

    Cell Theory

    • All living things are composed of one or more cells
    • Cells are the basic unit of structure and organization in organisms
    • Cells come from pre-existing cells (Omnis cellula e cellula).

    Cells

    • Open systems focused on self-maintenance and reproduction
    • Exchange of matter and energy with the environment
    • Obtain energy to maintain a stable state
    • Genetic material (inherited from the parent cell) stores information for structure and function
    • Cells adapt to environmental changes (e.g., chemical composition, presence of nutrients, toxins)

    Biochemical Assemblies

    • Nucleo-proteins: Association of nucleic acid and protein
    • Glyco-proteins: Consist of both proteins and carbohydrates
    • Lipo-proteins: Consist of proteins and lipids.

    Protein Denaturation

    • A protein loses its function when it's denatured.
    • Denaturation involves changes to secondary and tertiary structure (but not peptide bonds)
    • Denaturation can be reversible or irreversible depending on the conditions.

    Enzymes

    • Proteins that catalyze biochemical reactions
    • Lower activation energy => increased reaction rate
    • Are highly specific to their substrates
    • Isozymes catalyze the same reaction but differ in amino acid sequence.
    • Allosteric Regulation: Enzymes can be regulated.

    Cell Signaling

    • Govern basic cellular activities and coordinates cell actions
    • Signals include hormones, neurotransmitters, and cytokines
    • Signals bind to receptors to initiate cascade of cellular responses.

    Biomembranes

    • Selectively permeable barrier
    • Consist of a phospholipid bilayer
    • Various proteins embedded (integral and peripheral) for specialized functions
    • Cholesterol modulates fluidity.
    • Lipids and proteins arranged asymmetrically in the bilayer.

    Cell Adhesion and Communication

    • Integrins, cadherins, tight, adherens, and gap junctions connect cells and the extracellular matrix.
    • Junctions determine cell shape and movement.

    Cell Organelles

    • Detailed descriptions of various cell organelles, including their structure, functions, and roles in cellular processes.
    • Rough ER: protein synthesis.
    • Smooth ER: lipid synthesis.
    • Golgi apparatus: modifies, sorts, and packages proteins and lipids.
    • Lysosomes: contain digestive enzymes.
    • Mitochondria: produce energy (ATP) via oxidative phosphorylation.
    • Cytoskeleton (microtubules, microfilaments, intermediate filaments): maintaining cell shape and movement.

    Cell Division: The Cell Cycle

    • Interphase: G1, S, G2 (growth, DNA replication, and preparation for division)
    • Mitosis (nuclear division), cytokinesis (cytoplasmic division)
    • Control mechanisms (e.g., checkpoints) ensure accuracy and prevent uncontrolled cell growth

    DNA and Chromosomes

    • Details about chromosome structure, including nucleosomes and chromatin organization
    • Various types of chromosomal aberrations

    Gametogenesis

    • Formation of egg and sperm
    • Meiosis (reductional division) produces haploid gametes
    • Spermatogenesis (male) and oogenesis (female) pathways

    Fertilization

    • Union of egg and sperm
    • Steps of fertilization

    Cell Death

    • Apoptosis: programmed cell death, important for development & homeostasis
    • Necrosis: uncontrolled cell death, often caused by infections, injuries

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    Description

    Test your understanding of the glycocalyx and its functions in cellular activity. This quiz also covers the properties of plasma membranes, membrane potential, and the hierarchy of living systems. Challenge yourself to identify the roles of different types of organisms and systems in multicellular life.

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