Cell Biology Overview
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Questions and Answers

What role do centrioles play during cell division?

  • They synthesize proteins necessary for cell division.
  • They form the spindle fibers that pull chromosomes to the poles. (correct)
  • They are responsible for DNA replication.
  • They maintain the cell's shape.

Which component of the cytoskeleton is involved in cell contraction and cytokinesis?

  • Intermediate Filaments
  • Microtubules
  • Centrosomes
  • Microfilaments (correct)

How many microtubules are present in each centriole, based on their structure?

  • 45 microtubules
  • 36 microtubules
  • 18 microtubules
  • 27 microtubules (correct)

What is the primary function of intermediate filaments in the cytoskeleton?

<p>To provide structural support to the cell (C)</p> Signup and view all the answers

Which protein is primarily associated with microtubules in the cytoskeleton?

<p>Tubulin (D)</p> Signup and view all the answers

What is the primary function of the cell membrane?

<p>To control the passage of molecules in and out of the cell (B)</p> Signup and view all the answers

What does the nucleus primarily contain?

<p>Chromatin (DNA) (A)</p> Signup and view all the answers

Which organelle is responsible for ATP production?

<p>Mitochondrion (B)</p> Signup and view all the answers

What role do ribosomes play within the cell?

<p>Protein synthesis (A)</p> Signup and view all the answers

What is the function of the Golgi Complex?

<p>Sorting and packaging of proteins and lipids (D)</p> Signup and view all the answers

Which structure is involved in the synthesis and processing of proteins?

<p>Rough Endoplasmic Reticulum (C)</p> Signup and view all the answers

What is the main role of the lysosome?

<p>Breaking down cellular waste products (A)</p> Signup and view all the answers

What structure is responsible for movement in certain cells?

<p>Flagellum (B)</p> Signup and view all the answers

What is the primary function of mitochondria in a cell?

<p>ATP production (D)</p> Signup and view all the answers

Which of the following correctly describes the structure of the rough endoplasmic reticulum (RER)?

<p>A series of interconnected membranes with ribosomes (B)</p> Signup and view all the answers

What type of molecules does the smooth endoplasmic reticulum (SER) primarily synthesize?

<p>Lipids (B)</p> Signup and view all the answers

What is the function of the Golgi apparatus in a cell?

<p>Processing and packaging of proteins and lipids (B)</p> Signup and view all the answers

What is the main function of lysosomes in a cell?

<p>Digestion of cellular waste products (D)</p> Signup and view all the answers

The outer membrane of mitochondria is described as:

<p>Smooth and continuous (D)</p> Signup and view all the answers

In what form do secretory vesicles arise after processing in the Golgi apparatus?

<p>From the trans face of the Golgi (D)</p> Signup and view all the answers

Which type of lysosome is formed by the fusion of a primary lysosome with a phagosome?

<p>Secondary lysosome (D)</p> Signup and view all the answers

How does the number of mitochondria relate to cell activity?

<p>Directly proportional (C)</p> Signup and view all the answers

Which process describes the digestion of foreign particles by lysosomes?

<p>Heterophagy (B)</p> Signup and view all the answers

What is one function of the smooth endoplasmic reticulum (SER)?

<p>Calcium storage (A)</p> Signup and view all the answers

What happens to a cell when it undergoes autolysis?

<p>The cell digests itself due to damage or unnecessity (A)</p> Signup and view all the answers

Where are lysosomes synthesized within the cell?

<p>Rough endoplasmic reticulum (D)</p> Signup and view all the answers

What structural feature distinguishes ribosomes from lysosomes?

<p>Lysosomes are formed from vesicles while ribosomes are not (D)</p> Signup and view all the answers

What is the fate of cellular debris after being digested by lysosomes?

<p>It becomes a residual body (A)</p> Signup and view all the answers

What is the role of hydrolytic enzymes found in lysosomes?

<p>To catalyze the breakdown of waste products and cellular debris (B)</p> Signup and view all the answers

Flashcards

Cell Membrane

The cell membrane is a thin layer surrounding the cell, composed of phospholipids and proteins. It acts as a gatekeeper, controlling what enters and exits the cell.

Nucleus

The nucleus is the control center of the cell, containing the genetic material (DNA) and directing cellular activities.

Cytoplasm

The cytoplasm is a jelly-like substance filling the cell, providing a medium for organelles to function and move.

Ribosomes

Ribosomes are small, granular structures involved in protein synthesis, essentially translating genetic code into functional proteins.

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Mitochondria

Mitochondria are bean-shaped organelles responsible for generating energy (ATP) for the cell's activities.

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RER

The rough endoplasmic reticulum (RER) is a network of membranes studded with ribosomes, responsible for protein synthesis and modifications.

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SER

The smooth endoplasmic reticulum (SER) is a network of membranes without ribosomes, involved in lipid and steroid synthesis and detoxification.

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Golgi Complex

The Golgi complex is a stack of flattened, membrane-bound sacs responsible for sorting, packaging, and distributing proteins and lipids.

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Endoplasmic Reticulum (ER)

A network of interconnected membranes that extend from the nuclear membrane through the cytoplasm.

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Rough Endoplasmic Reticulum (RER)

A type of ER with ribosomes attached, responsible for synthesizing, storing, and delivering proteins.

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Smooth Endoplasmic Reticulum (SER)

A type of ER without ribosomes attached, involved in lipid synthesis, glycogen storage, calcium storage, and drug detoxification.

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Golgi Apparatus (GA)

A stack of flattened, membrane-bound sacs called cisternae. Involved in processing and packaging of proteins and lipids.

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Sacculus (Flattened Vesicles)

Flattened vesicles in the Golgi apparatus arranged in stacks. They have two faces: cis (immature, towards ER) and trans (mature, towards cell exterior).

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Transfer Vesicle (microvesicle)

Small vesicles that arise from the RER and carry synthesized proteins to the Golgi apparatus.

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What are centrioles?

Small, cylindrical structures found near the nucleus, essential for cell division. They form spindle fibers which pull chromosomes to the poles during cell division.

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What is a centrosome?

Two centrioles positioned at right angles to each other come together to form a centrosome.

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What is the cytoskeleton?

A network of protein fibers in the cytoplasm that gives shape to the cell, helps move organelles, and aids in cell division.

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What are microfilaments?

The thinnest filaments of the cytoskeleton, made of actin. They are involved in cell movement, contraction, and cytokinesis.

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What are microtubules?

The thickest filaments of the cytoskeleton, made of tubulin. They are involved in cell movement, organelle transport, and the formation of spindle fibers during cell division.

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Acrosome

A specialized vesicle in sperm that contains enzymes that help break down the outer layer of the egg during fertilization.

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Lysosome

Small, membrane-bound organelles containing enzymes for breaking down cellular waste, worn-out parts, and foreign invaders. They are like the cell's recycling and garbage disposal centers.

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Primary lysosome

Newly formed lysosomes filled with enzymes, waiting to be activated.

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Secondary lysosome

A lysosome that has fused with a phagosome or autophagosome, actively digesting cellular debris or waste products.

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Heterophagy

The process where lysosomes engulf and break down foreign particles like bacteria or viruses.

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Autophagy

The process where lysosomes break down worn-out parts of the cell, like old mitochondria, for recycling.

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Autolysis

The process of self-destruction, where lysosomes release enzymes to completely break down the cell, often when the cell is damaged or no longer needed.

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Phagosome

A vesicle formed when the cell engulfs a foreign object, like a bacteria, for the lysosome to digest. It's like a 'catcher' for invaders.

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Study Notes

Cell Biology

  • Cell biology is the study of cells, their structure, function, and interactions.

Cell Structure

  • A cell is composed of a cell membrane, nucleus, and cytoplasm.
  • The cell membrane encloses the cell.
  • The nucleus contains genetic material (DNA).
  • The cytoplasm is the area between the membrane and the nucleus.

Cytoplasm

  • The cytoplasm consists of organelles, matrix, and non-living inclusions.
  • Organelles perform specific functions within the cell.
  • Membranous organelles have membranes that separate their contents from the cytoplasm.
  • Non-membranous organelles do not have these membranes.

Organelles

  • Membranous:
    • Mitochondria: The main energy source of the cell. Their structure includes a double membrane. The inner membrane is folded into cristae, increasing the surface area for energy production. The number of mitochondria and cristae are directly proportional to cell activity.
    • Endoplasmic Reticulum (ER): A network of membrane-bound tubules and flattened sacs (cisternae). There are two types: rough ER (RER) has ribosomes attached to its surface and is involved in protein synthesis; smooth ER (SER) lacks ribosomes and is involved in lipid synthesis, carbohydrate metabolism, and drug detoxification.
    • Golgi apparatus (GA): A series of flattened sacs (cisternae) involved in processing, packaging, and transporting proteins and lipids. It has a cis and trans face.
    • Lysosomes: Contain digestive enzymes and are involved in breaking down waste materials.
  • Non-Membranous:
    • Ribosomes: Small organelles that synthesize proteins. There are free ribosomes (in the cytoplasm) and attached ribosomes (on the RER).
    • Centrioles: Cylindrical organelles that play a role in cell division by forming spindle fibers.
    • Cytoskeleton: A network of protein fibers that maintain cell shape, support the cell, and move organelles. Types include microfilaments, intermediate filaments, and microtubules.

Mitochondria

  • Shape: Variable (e.g., granular, rod-like)
  • Structure: Membranous vesicle surrounded by a double membrane. The outer membrane is smooth; the inner membrane folds into cristae.
  • Function: Main source of energy production in the cell.

Endoplasmic Reticulum (ER)

  • Structure: Series of interconnecting membranes in the form of tubules or cisternae.
  • Rough Endoplasmic Reticulum (RER): Surface attached with ribosomes, close to nucleus, function in protein synthesis, storage, and delivery.
  • Smooth Endoplasmic Reticulum (SER): Not attached with ribosomes, far from nucleus, involved in lipid synthesis, glycogen storage, detoxification and, calcium storage.

Golgi Apparatus (GA)

  • Structure: System of flattened sacs (cisternae), cis face receives proteins and trans face sends out processed proteins.
  • Function: Processes, packages, and transports proteins and lipids. It is responsible for making secretory vesicles and can form lysosomes.

Lysosomes

  • Structure: Membranous vesicles containing hydrolytic enzymes (e.g., proteases, lipases).
  • Function: Involved in digestion of foreign particles (heterophagy), cellular waste and organelles (autophagy), and cellular death (autolysis). They play a significant role in breaking down cellular materials.

Ribosomes

  • Structure: Dense granules of nucleoprotein (rRNA + protein), composed of two subunits (large and small) Free in cytosol or bound to the RER.
  • Function: Synthesize proteins. Free ribosomes make proteins for use inside the cell; attached ribosomes make proteins for secretion outside the cell.

Centrioles

  • Structure: Cylindrical, composed of 9 bundles of microtubules (9x3 = 27 microtubules), organized into a centrosome.
  • Function: Play a crucial role in cell division by forming spindle fibers that move chromosomes to opposite poles.

Cytoskeleton

  • Structure: Network of protein fibers (microtubules, intermediate filaments, and microfilaments).
  • Function: Maintains cell shape, supports the cell, holds and moves organelles, involved in cell division.

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