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Questions and Answers
What is the primary role of free ribosomes in the cell?
What is the primary role of free ribosomes in the cell?
Which structure is NOT considered a membranous organelle?
Which structure is NOT considered a membranous organelle?
What is the cytoplasmic matrix composed of?
What is the cytoplasmic matrix composed of?
Which of the following describes the structure of microtubules?
Which of the following describes the structure of microtubules?
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What characterizes attached ribosomes compared to free ribosomes?
What characterizes attached ribosomes compared to free ribosomes?
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Which of the following is a correct pairing of structure and function?
Which of the following is a correct pairing of structure and function?
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Centriole and cilia are types of which cellular structure?
Centriole and cilia are types of which cellular structure?
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What can be said about the cytoplasmic inclusions?
What can be said about the cytoplasmic inclusions?
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Which type of filament is primarily responsible for muscle contraction?
Which type of filament is primarily responsible for muscle contraction?
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What are the functions of intermediate filaments?
What are the functions of intermediate filaments?
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Where is glycogen primarily stored in the body?
Where is glycogen primarily stored in the body?
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Which structures are classified as inclusions within the cytoplasm?
Which structures are classified as inclusions within the cytoplasm?
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Which of the following describes exogenous pigments?
Which of the following describes exogenous pigments?
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What is the primary function of microtubules?
What is the primary function of microtubules?
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What structural feature distinguishes centrioles when viewed in cross-section?
What structural feature distinguishes centrioles when viewed in cross-section?
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Which parts comprise a cilium?
Which parts comprise a cilium?
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What unique structure is formed by microtubules during cell division?
What unique structure is formed by microtubules during cell division?
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Which statement accurately describes the appearance of centrioles using electron microscopy?
Which statement accurately describes the appearance of centrioles using electron microscopy?
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What is the role of the basal body in the structure of cilia?
What is the role of the basal body in the structure of cilia?
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Which method is commonly used to visualize microtubules?
Which method is commonly used to visualize microtubules?
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What type of organelle are microtubules classified as?
What type of organelle are microtubules classified as?
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Study Notes
Cell Structure
- The cell is the basic unit of life, consisting of the nucleus and cytoplasm.
- The cytoplasm contains the cytoplasmic matrix, cell organelles and inclusions.
Cytoplasmic Matrix
- This gel-like substance fills the space between organelles and inclusions.
- It's a colloidal solution with soluble proteins, amino acids, carbohydrates, enzymes, minerals and ions.
Cell Organelles
- These are specialized structures within the cell responsible for specific functions.
- They are categorized as either membranous or non-membranous.
Non-Membranous Organelles
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Ribosomes:
- Composed of rRNA and protein, synthesized in the nucleolus.
- Too small to be seen under a light microscope (LM) but appear as dense granules under an electron microscope (EM).
- Can be free or attached to the endoplasmic reticulum (ER).
- Free ribosomes synthesize proteins for cytoplasmic use.
- Attached ribosomes synthesize proteins for export.
-
Cytoskeleton:
- Provides structural support and helps maintain cell shape.
- Facilitates intracellular transport.
- Involved in cell division and movement of organelles.
- Composed of microtubules and filaments.
Microtubules
- Straight, hollow tubes formed of tubulin.
- Responsible for supporting the cell, intracellular transport, formation of the mitotic spindle, centrioles, cilia, and flagella.
- Appear in bundles under special staining methods.
Centrioles
- Non-membranous organelles present near the nucleus in the centrosome.
- Appear as two dots near the nucleus under LM.
- Composed of 27 microtubules (9 triplets) in cross-section.
- Function in cell division, formation of microtubules, and the basal body of cilia and flagella.
Cilia
- Motile, hair-like structures covered by the cell membrane, extending from the surface of epithelial cells.
- Appear as striations under LM.
- Composed of a basal body, a shaft (axoneme) and rootlets.
- The basal body structure is identical to the centriole.
- The shaft consists of 20 microtubules (9 doublets and 2 singlets).
- The rootlets anchor the basal body and shaft to the cytoplasm.
Filaments
- Tiny thread-like structures responsible for elasticity and contractility of the cytoplasm.
- Appear under silver stain (LM).
- Classified as:
- Microfilaments (thin filaments): Actin filaments found in muscle cells, microvilli, and the cell division ring.
- Thick filaments: Myosin filaments present in muscle cells.
- Intermediate filaments: Variable functions and distribution, including:
- Desmin in muscle cells
- Keratin in epithelial cells
- Neurofilaments in nerve cells
- Glial filaments in neuroglia cells
Inclusions (Cytoplasmic Deposits)
- Non-living, temporary components of the cytoplasm that are not essential for cell viability.
- Examples include:
- Stored food (glycogen and lipids)
- Pigments (exogenous and endogenous)
- Crystals
Glycogen
- The storage form of carbohydrates in the body.
- Abundant in muscle and liver cells.
- Not visible under H&E stain, but stained magenta with PAS.
- Appear as electron-dense rosettes under EM.
Lipids (Fat)
- Primarily stored in adipocytes.
- Not visible under H&E stain, but stained orange with Sudan III.
- Appear as rounded, electron-dense droplets under EM.
Pigments
- Color-producing substances that can be exogenous or endogenous.
Exogenous Pigments
- Taken from outside the body.
- Examples include:
- Lipochromes (e.g., carotene)
- Dust
- Tattoo ink
Endogenous Pigments
- Produced within the body.
- Examples include:
- Hemoglobin
- Melanin
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Description
Test your knowledge on cell structure and the functions of various organelles. This quiz covers the cytoplasmic matrix, ribosomes, and the classification of organelles. Dive deep into the fascinating world of cells and their components.