Cell Biology: Mitosis Quiz

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Questions and Answers

What is the primary role of the mitotic spindle during prophase?

  • To dissolve the nuclear envelope
  • To align chromosomes at the metaphase plate
  • To separate chromatids to each new daughter cell (correct)
  • To condense chromatin into visible chromosomes

During which stage do the chromosomes appear maximally condensed?

  • Anaphase
  • Telophase
  • Metaphase (correct)
  • Prophase

What happens to the nucleolus and nuclear envelope during prophase?

  • They completely dissolve (correct)
  • They move to the equatorial plane
  • They begin to reform
  • They remain intact

What connects sister chromatids together during metaphase?

<p>Cohesin proteins (D)</p> Signup and view all the answers

What is the metaphase plate?

<p>The plane where chromosomes align midway between cell poles (C)</p> Signup and view all the answers

Flashcards

Prophase: Chromatin Condensation

Chromatin, the thread-like DNA, coils and thickens, becoming visible chromosomes under a microscope during the cell cycle.

Prophase: Nuclear Envelope Disappearance

The membrane surrounding the nucleus, disappears in this stage.

Prophase: Centrosome Movement

Two centrosomes, each containing centrioles, move to opposite poles of the cell.

Prophase: Spindle Formation

Microtubules assemble to form a dynamic network called the mitotic spindle (sometimes referred to as the spindle apparatus) that will help in separating the chromosomes and forming new cells.

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Metaphase: Chromosomes Alignment

Chromosomes line up at the center of the cell, forming a plane called the metaphase plate.

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Metaphase: Sister Chromatids Attachment

Sister chromatids, identical copies of the chromosome, remain attached by cohesin proteins.

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Metaphase: Chromosome Condensation

Chromosomes are at their most condensed form in this stage.

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Study Notes

Prophase

  • Chromatin condenses, forming visible chromosomes.
  • The nucleolus and nuclear envelope disappear.
  • Centrosomes move to opposite poles of the cell.
  • A mitotic spindle forms, with each spindle fiber responsible for separating chromatids to daughter cells.

Metaphase

  • Chromosomes align along the metaphase plate (equatorial plane).
  • Sister chromatids remain attached by cohesin proteins.
  • Chromosomes are most condensed during metaphase.

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