Cell structure and division: Mitosis

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Questions and Answers

What is the primary reason cell division occurs?

  • To increase the surface area to volume ratio (correct)
  • To maintain a constant surface area to volume ratio
  • To decrease the surface area to volume ratio
  • To eliminate the surface area to volume ratio

During the S phase of interphase, the cell primarily focuses on growth and producing new organelles.

False (B)

During which phase of mitosis do sister chromatids separate and move to opposite poles of the cell?

Anaphase

The structure that holds sister chromatids together is called the ________.

<p>centromere</p> Signup and view all the answers

Match each phase of mitosis with its key event:

<p>Prophase = Chromosomes condense and become visible Metaphase = Chromosomes align along the middle of the cell Anaphase = Sister chromatids separate and move to opposite poles Telophase = Nuclear envelope reforms around separated chromosomes</p> Signup and view all the answers

Which of the following structures is responsible for organizing and moving chromosomes during mitosis?

<p>Spindle fiber (B)</p> Signup and view all the answers

External regulators of the cell cycle are substances within the cell that respond to events occurring inside the cell.

<p>False (B)</p> Signup and view all the answers

What is the process of programmed cell death called?

<p>Apoptosis</p> Signup and view all the answers

__________ are proteins that regulate the timing of the cell cycle in eukaryotic cells.

<p>Cyclins</p> Signup and view all the answers

What is a characteristic of a 'benign' tumor?

<p>It remains localized and does not spread (A)</p> Signup and view all the answers

A malignant tumor is a non-cancerous mass of cells that does not spread to other parts of the body.

<p>False (B)</p> Signup and view all the answers

What is the process by which cells become specialized in structure and function?

<p>Differentiation</p> Signup and view all the answers

__________ stem cells are able to develop into any type of cell in the body.

<p>Embryonic</p> Signup and view all the answers

Which type of stem cell is 'multipotent'?

<p>Adult stem cells (C)</p> Signup and view all the answers

Adult stem cells are pluripotent, meaning they can differentiate into any cell type in the body.

<p>False (B)</p> Signup and view all the answers

Match each checkpoint with its primary function:

<p>G1 checkpoint = Checks for cell size, nutrients, growth factors, and DNA damage G2 checkpoint = Checks for DNA replication completeness and damage M checkpoint = Checks for chromosome attachment to spindle fibers</p> Signup and view all the answers

At which checkpoint does the cell make the decision to proceed with cell division or enter a resting phase?

<p>G1 checkpoint (B)</p> Signup and view all the answers

DNA wraps around ribosome proteins and condenses to form a chromosome.

<p>False (B)</p> Signup and view all the answers

What does 'SA to V ratio' stand for in the context of cell size?

<p>Surface Area to Volume ratio</p> Signup and view all the answers

The phase of the cell cycle where the cell grows and prepares for DNA replication is called the ________ phase.

<p>G1</p> Signup and view all the answers

Flashcards

SA to V ratio

The ratio of a cell's surface area to its volume. A high ratio is more efficient for transport.

Why does cell division occur?

Cell division occurs for growth, repair, and reproduction.

Interphase

The stage of the cell cycle where the cell grows, replicates its DNA, and prepares for division. Consists of G1, S, and G2 phases.

G1 Phase

The first gap phase of interphase, where the cell grows and performs its normal functions.

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S Phase

The synthesis phase of interphase, where DNA replication occurs.

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G2 Phase

The second gap phase of interphase, where the cell prepares for mitosis.

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Mitosis

Cell division in which the nucleus divides into nuclei containing the same number of chromosomes

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Prophase

The first phase of mitosis, where the chromosomes condense and become visible, and the nuclear envelope breaks down.

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Metaphase

The second phase of mitosis, where the chromosomes line up along the metaphase plate.

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Anaphase

The third phase of mitosis, where the sister chromatids separate and move to opposite ends of the cell.

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Telophase

The final phase of mitosis, where the chromosomes decondense, and the nuclear envelope reforms.

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Cytokinesis

The division of the cytoplasm to form two separate daughter cells.

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Centriole

A structure in animal cells involved in cell division.

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Centromere

The constricted region joining two sister chromatids that make up a chromosome.

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Spindle fiber

A structure during cell division that separates the chromosomes.

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Daughter cells

New cells formed by the division of a parent cell.

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Sister chromatids

Two identical copies of a single chromosome that are connected by a centromere.

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Internal regulators

Signals within the cell that regulate the cell cycle.

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External regulators

Signals from outside the cell that regulate the cell cycle.

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Apoptosis

Programmed cell death; a process where cells self-destruct.

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Study Notes

  • Cell size is limited by the surface area to volume ratio
  • Cell division occurs for growth, repair, and reproduction

Chromosomes

  • DNA wraps around histone proteins
  • This condenses to form a chromosome

Cell Division: Interphase

  • This is preparation for division and includes:
    • G1 phase: Cell growth and normal functions
    • S phase: DNA replication
    • G2 phase: Preparation for mitosis

Cell Division: Mitosis

  • Prophase:
    • Chromosomes become visible
    • The nuclear envelope disappears
    • Spindle fibers form
  • Metaphase:
    • Chromosomes line up in the middle of the cell
    • Spindle fibers attach to the centromeres
  • Anaphase:
    • Sister chromatids separate and move to opposite ends of the cell
  • Telophase:
    • Chromosomes begin to uncoil
    • Nuclear envelopes reform
  • Cytokinesis:
    • The cytoplasm divides, forming two identical daughter cells

Structures to Know

  • Centriole: Organizes spindle fibers
  • Centromere: Holds sister chromatids together
  • Spindle fiber: Moves chromosomes during cell division
  • Daughter cells: The result of cell division
  • Sister chromatids: Identical copies of a chromosome

Regulation

  • Internal regulators: Respond to events inside the cell
  • External regulators: Respond to events outside the cell
  • Apoptosis: Programmed cell death, occurring in three steps

Checkpoints

  • G1 checkpoint: Checks for cell size, nutrients, growth factors, and DNA damage
  • G2 checkpoint: Checks for DNA replication and damage
  • M checkpoint: Checks for chromosome attachment to spindle fibers

Cyclins

  • Proteins that regulate the cell cycle

Cancer

  • Results from uncontrolled cell growth

Tumors

  • Benign tumor: Non-cancerous and does not spread
  • Malignant tumor: Cancerous and can spread to other parts of the body

Development

  • Embryo: Early stage of development
  • Differentiation: Cells become specialized in structure and function

Stem Cells

  • Unspecialized cells from which differentiated cells develop
    • Embryonic stem cells (pluripotent): Can become any type of cell in the body
    • Adult stem cells (multipotent): Can become a limited number of cell types

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