Cell Biology study area 1
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Questions and Answers

Which of the following is NOT a fundamental attribute shared by all living things?

  • Respiration
  • Reproduction
  • Photosynthesis (correct)
  • Sensitivity

Stable environmental conditions, such as consistent temperature and pH levels, are crucial for the survival of living organisms.

True (A)

Besides an energy source, what other crucial substance is required for biochemical reactions and cellular transport within living organisms?

Liquid water

The process of converting glucose into ATP to power cellular activities is known as __________.

<p>Respiration</p> Signup and view all the answers

If an organism thrives in extremely high salinity conditions, which cellular adaptation is MOST crucial?

<p>Enhanced excretion mechanisms (A)</p> Signup and view all the answers

Which of the following is NOT a tenet of the cell theory?

<p>Cells can spontaneously generate from non-living matter. (A)</p> Signup and view all the answers

Prokaryotic cells contain membrane-bound organelles such as mitochondria and endoplasmic reticulum.

<p>False (B)</p> Signup and view all the answers

What is the region in a prokaryotic cell where DNA is located called?

<p>nucleoid</p> Signup and view all the answers

The cell wall of prokaryotes is made of peptidoglycan, while the __________ is made of polysaccharides.

<p>capsule</p> Signup and view all the answers

Match the scientist with their contribution to the cell theory:

<p>Anton van Leeuwenhoek = Discovered bacteria Robert Hooke = Coined the term 'cell' Theodor Schwann = Contributed to the development of the cell theory Matthias Schleiden = Contributed to the development of the cell theory Robert Remack = Proved that cells come from pre-existing cells.</p> Signup and view all the answers

Which of the following is NOT found in eukaryotic cells?

<p>Capsule (B)</p> Signup and view all the answers

Why are there no large unicellular organisms?

<p>As size increases, the surface area to volume ratio decreases, limiting efficient exchange with the environment. (D)</p> Signup and view all the answers

Extremely Difficult: Calculate the surface area to volume ratio of a hypothetical, perfectly spherical cell with a radius of 100 micrometers. Express your answer rounded to the nearest whole number.

<p>0.03</p> Signup and view all the answers

What happens to the surface area to volume ratio (SA:V) as a cube increases in size?

<p>The SA:V ratio decreases. (B)</p> Signup and view all the answers

A cell with a larger cytoplasm has a higher surface area to volume ratio compared to a cell with smaller cytoplasm.

<p>False (B)</p> Signup and view all the answers

Why do larger organisms often require specialized transport systems like a circulatory system?

<p>To overcome limitations of diffusion due to decreased SA:V ratio.</p> Signup and view all the answers

For a cube with side length L, the surface area is calculated by $SA = 6L^2$, and the volume is calculated by $V= ______$.

<p>L^3</p> Signup and view all the answers

Match the organism with its typical surface area to volume ratio adaptation:

<p>Bacteria = Relies on diffusion due to high SA:V ratio Humans = Possesses specialized exchange surfaces to increase SA:V ratio</p> Signup and view all the answers

What is the relationship between a cell's metabolic needs and its ability to transport materials as the volume of the cell increases?

<p>Metabolic needs increase faster than the ability to transport materials. (C)</p> Signup and view all the answers

The rate at which nutrients enter and wastes leave a cell is generally directly proportional to cell size.

<p>False (B)</p> Signup and view all the answers

Consider two cubes: Cube A has a side length of 2 units, and Cube B has a side length of 4 units. What best describes the relationship between their surface area to volume ratios?

<p>The surface area to volume ratio of Cube A is double that of Cube B. (D)</p> Signup and view all the answers

What is the primary function of microvilli in cells lining the small intestine?

<p>To increase the rate of nutrient absorption (C)</p> Signup and view all the answers

An obligate endosymbiont can survive independently outside of its host cell.

<p>False (B)</p> Signup and view all the answers

What is the main function of ribosomes?

<p>protein synthesis</p> Signup and view all the answers

The process by which cells break down non-functioning organelles is called __________.

<p>autophagy</p> Signup and view all the answers

Match the following organelles with their primary functions:

<p>Mitochondria = ATP production Endoplasmic Reticulum = Protein and lipid synthesis Golgi Apparatus = Protein packaging and modification Lysosomes = Intracellular digestion</p> Signup and view all the answers

Which of the following is NOT a function of the cytoskeleton?

<p>Controlling DNA replication (B)</p> Signup and view all the answers

Red blood cells contain numerous mitochondria to support their high energy demands.

<p>False (B)</p> Signup and view all the answers

What type of molecule primarily composes the cell membrane?

<p>phospholipids</p> Signup and view all the answers

__________ proteins span the width of the plasma membrane.

<p>transmembrane</p> Signup and view all the answers

Which of the following is the primary function of the enzyme catalase found in peroxisomes?

<p>Breakdown of hydrogen peroxide (A)</p> Signup and view all the answers

Glycolipids on the plasma membranes play a role in cell to cell communication.

<p>True (A)</p> Signup and view all the answers

What are the two main components of the plasma membrane?

<p>phospholipids and proteins</p> Signup and view all the answers

The rough ER is characterized by the presence of __________ on its surface.

<p>ribosomes</p> Signup and view all the answers

Which of the following best describes the function of cholesterol within the cell membrane?

<p>Maintaining membrane fluidity (D)</p> Signup and view all the answers

How does the arrangement of phospholipids in the cell membrane contribute to its barrier function, and what property of the phospholipid molecules is crucial for this arrangement?

<p>Phospholipids arrange themselves into a bilayer with the hydrophobic lipid tails facing inward and hydrophilic phosphate heads facing outward, creating a barrier preventing polar molecules and ions from passively diffusing across.</p> Signup and view all the answers

Which of the following structures is NOT found in prokaryotic cells?

<p>Nuclear membrane (B)</p> Signup and view all the answers

According to the original cell theory, all cells arise spontaneously.

<p>False (B)</p> Signup and view all the answers

What is the primary component of the cell walls in prokaryotic cells?

<p>peptidoglycan</p> Signup and view all the answers

The region in a prokaryotic cell where DNA is located is called the ______.

<p>nucleoid</p> Signup and view all the answers

Match the following scientists with their contribution to cell theory:

<p>Theodor Schwann = Developed the cell theory along with Matthias Schleiden Matthias Schleiden = Developed the cell theory along with Theodor Schwann Anton van Leeuwenhoek = Discovered bacteria (animalcules) Robert Hooke = Coined the term 'cell' Robert Remak = Proved that all cells come from pre-existing cells</p> Signup and view all the answers

What characteristic distinguishes eukaryotic cells from prokaryotic cells?

<p>Presence of membrane-bound organelles (B)</p> Signup and view all the answers

Which of the following cell types can change their shape?

<p>White blood cells (C)</p> Signup and view all the answers

What is the main reason there are no enormous unicellular organisms?

<p>Surface area to volume ratio limitations (B)</p> Signup and view all the answers

Which factor directly affects the rate of diffusion across a cell membrane due to its influence on molecular movement?

<p>Temperature (B)</p> Signup and view all the answers

Channel proteins, unlike carrier proteins, change shape to facilitate the transport of substances across the cell membrane.

<p>False (B)</p> Signup and view all the answers

What property of the phospholipid tails in the cell membrane's bilayer allows it to be fluid and flexible?

<p>hydrophobic</p> Signup and view all the answers

Proteins that span the entire width of the plasma membrane are known as transmembrane or ______ proteins.

<p>integral</p> Signup and view all the answers

Match each protein function with its role in the cell membrane:

<p>Transport = Facilitates movement of hydrophilic substances across the membrane Reception = Binds to signaling molecules Anchorage = Connects cytoskeleton to the extracellular matrix Cell identity = Marks the cell as 'self'</p> Signup and view all the answers

Which type of protein is directly involved in cell-to-cell communication via the formation of gap junctions?

<p>Proteins involved with intercellular joinings (C)</p> Signup and view all the answers

Enzymes alter themselves permanently while catalyzing biochemical reactions.

<p>False (B)</p> Signup and view all the answers

What molecule in the cell membrane helps to maintain stability and reduce fluidity at normal body temperatures?

<p>cholesterol</p> Signup and view all the answers

What is the main function of glycoproteins and glycolipids on the cell surface?

<p>Cell Identity, Intercellular Joinings and Tissue recognition (D)</p> Signup and view all the answers

Facilitated diffusion requires the use of special protein _______ to move molecules across the cell membrane.

<p>transporters</p> Signup and view all the answers

Which of the following cellular components is NOT present in mature red blood cells?

<p>Mitochondria (A)</p> Signup and view all the answers

Active transport moves molecules from an area of high concentration to an area of low concentration.

<p>False (B)</p> Signup and view all the answers

The breakdown of non-functioning cell organelles through digestion within the cell is known as ________.

<p>autophagy</p> Signup and view all the answers

Match the organelle with its primary function:

<p>Nucleus = Houses DNA and controls gene expression Mitochondria = ATP production through cellular respiration Endoplasmic Reticulum = Protein and lipid synthesis Golgi Apparatus = Protein packaging and sorting</p> Signup and view all the answers

Which of the following is a key function of the smooth endoplasmic reticulum?

<p>Detoxification of harmful substances (D)</p> Signup and view all the answers

Ribosomes are enclosed within a membrane.

<p>False (B)</p> Signup and view all the answers

What two types of molecules compose ribosomes?

<p>rRNA and proteins</p> Signup and view all the answers

The organelle responsible for producing ribosomal RNA (rRNA) is the ________.

<p>nucleolus</p> Signup and view all the answers

Which of the components of the cytoskeleton is primarily responsible for cell movement?

<p>Microfilaments (C)</p> Signup and view all the answers

Peroxisomes use the enzyme catalase to break down hydrogen peroxide into water and oxygen.

<p>True (A)</p> Signup and view all the answers

What is one key difference between cilia and flagella in eukaryotic cells?

<p>number or length</p> Signup and view all the answers

The process by which large molecules are transported across the cell membrane using vesicles is called ________ transport.

<p>bulk</p> Signup and view all the answers

Which of the following factors does NOT affect the rate of diffusion across a cell membrane?

<p>Cell shape (B)</p> Signup and view all the answers

Which of the following is the correct chemical equation for cellular respiration?

<p>$C_6H_{12}O_6 + 6O_2 \rightarrow 6CO_2 + 6H_2O + ATP$ (D)</p> Signup and view all the answers

A plant bends towards a window to capture more sunlight. Which attribute of living things does this BEST exemplify?

<p>Sensitivity to stimuli (D)</p> Signup and view all the answers

Why is liquid water considered essential for life as we know it?

<p>It facilitates biochemical reactions and cellular transport. (A)</p> Signup and view all the answers

A scientist discovers a new organism in a deep-sea vent that respires sulfur instead of oxygen. Which of the fundamental requirements for life would this organism MOST challenge?

<p>Need for stable environmental conditions (C)</p> Signup and view all the answers

Which of the following processes is the MOST direct example of respiration in living organisms?

<p>Conversion of glucose into ATP. (B)</p> Signup and view all the answers

A population of bacteria doubles in size every 20 minutes under ideal conditions. Which characteristic of life does this BEST illustrate?

<p>Reproduction (A)</p> Signup and view all the answers

Which of the following organelles is responsible for modifying and packaging proteins into transport vesicles?

<p>Golgi apparatus (C)</p> Signup and view all the answers

An immune response is triggered when a cell does not display the correct ________ on its surface.

<p>Molecules (D)</p> Signup and view all the answers

What is the primary role of transport proteins or 'pumps' in active transport?

<p>To move molecules against their concentration gradient using ATP. (C)</p> Signup and view all the answers

How does the oxidation of fatty acids in peroxisomes contribute to cellular metabolism?

<p>By breaking down fatty acids, which can then be used for energy production. (A)</p> Signup and view all the answers

What is the role of the sodium-potassium pump in maintaining the resting membrane potential in neurons?

<p>It uses ATP to transport sodium and potassium ions against their concentration gradients. (B)</p> Signup and view all the answers

Which component of the cytoskeleton is primarily responsible for providing mechanical support and maintaining cell shape?

<p>Intermediate filaments (C)</p> Signup and view all the answers

Which of the following best describes the function of ribosomes?

<p>Synthesizing proteins based on mRNA sequences. (B)</p> Signup and view all the answers

If a poison prevents the Golgi apparatus from functioning, what cellular process will be MOST directly affected?

<p>Protein sorting and packaging (A)</p> Signup and view all the answers

What is the significance of the highly folded inner membrane (cristae) of the mitochondria?

<p>It increases the surface area for ATP production. (B)</p> Signup and view all the answers

If a cell were unable to perform autophagy, what would be the most likely consequence?

<p>Accumulation of damaged organelles and cellular debris (D)</p> Signup and view all the answers

Consider a cell with a high concentration of hydrophobic waste products. Which organelle would likely be most active in detoxifying these substances?

<p>Smooth endoplasmic reticulum (C)</p> Signup and view all the answers

Which of the following is a direct result of the breakdown of glycogen in the smooth endoplasmic reticulum (ER)?

<p>Release of glucose into the cell (C)</p> Signup and view all the answers

How do cilia and flagella contribute to the function of eukaryotic cells?

<p>By facilitating movement of the cell or movement of substances across the cell surface. (C)</p> Signup and view all the answers

Which of the following observations would indicate that a particular cell is highly active and requires a significant amount of energy?

<p>A high number of mitochondria. (C)</p> Signup and view all the answers

Which of the following cellular structures is primarily responsible for synthesizing proteins?

<p>Ribosomes (D)</p> Signup and view all the answers

According to the modern cell theory, which statement is MOST accurate regarding the origin of cells?

<p>All cells arise from pre-existing cells through cell division. (D)</p> Signup and view all the answers

Which of the following structures is NOT a characteristic of prokaryotic cells?

<p>Nuclear membrane (A)</p> Signup and view all the answers

What is the primary role of the capsule found in some prokaryotic cells?

<p>To protect the cell from phagocytosis and desiccation (A)</p> Signup and view all the answers

Why can some cells, like white blood cells and amoebas, change their shape?

<p>To move and perform specific functions, such as engulfing pathogens (B)</p> Signup and view all the answers

A cell's ability to efficiently exchange substances with its environment is MOST directly related to:

<p>The ratio of its surface area to volume (B)</p> Signup and view all the answers

A spherical cell with a radius of 5 micrometers has a surface area to volume ratio that allows for efficient nutrient exchange. If the cell's radius doubles to 10 micrometers, what happens to the surface area to volume ratio?

<p>It is halved. (C)</p> Signup and view all the answers

Which of the following BEST explains why larger, multicellular organisms require specialized transport systems, such as a circulatory system?

<p>To overcome the limitations of diffusion in delivering nutrients and removing wastes from distant cells (C)</p> Signup and view all the answers

How do cells lining the small intestine compensate for their relatively large size to maintain efficient nutrient absorption?

<p>By increasing the presence of microvilli to increase the surface area for absorption. (A)</p> Signup and view all the answers

Which of the following statements BEST describes the relationship between cell size and the rate of nutrient and waste transport?

<p>As cell size increases, the rate of nutrient entry and waste removal decreases. (C)</p> Signup and view all the answers

Which scientist provided evidence that all cells come from pre-existing cells, challenging a prevailing idea at the time?

<p>Robert Remak (B)</p> Signup and view all the answers

A researcher discovers a new unicellular organism. Initial observations reveal the presence of ribosomes, a cell wall, and a circular chromosome. Further analysis is MOST needed to determine if the organism also contains:

<p>A nucleus (D)</p> Signup and view all the answers

How does the presence of microvilli on the surface of certain cells enhance their functionality?

<p>By increasing the surface area available for absorption. (A)</p> Signup and view all the answers

Based on the principles of surface area to volume ratio, which cellular adaptation would be MOST beneficial for maximizing the exchange of substances between a cell and its environment?

<p>Developing numerous folds and projections on the cell membrane. (A)</p> Signup and view all the answers

Considering the limitations imposed by the surface area to volume ratio, what evolutionary advantage might multicellularity provide to organisms?

<p>It allows for the development of specialized cells and transport systems to overcome diffusion limitations. (D)</p> Signup and view all the answers

Which of the following transport mechanisms relies on a change in the shape of the transport protein to facilitate movement across the cell membrane?

<p>Facilitated diffusion via carrier proteins (D)</p> Signup and view all the answers

How does an increase in temperature affect the rate of diffusion, and why?

<p>It increases the rate because higher temperatures cause faster molecular movement. (B)</p> Signup and view all the answers

In the context of osmosis, what condition describes a cell surrounded by a solution with a higher solute concentration compared to the inside of the cell?

<p>Hypertonic (C)</p> Signup and view all the answers

Why does the cell membrane's structure allow red blood cells to squeeze through narrow capillaries?

<p>The viscous, fluid nature of the phospholipid tails allows for flexibility. (D)</p> Signup and view all the answers

Which of the following is a primary function of integral proteins in the cell membrane?

<p>Transporting hydrophilic substances across the membrane (A)</p> Signup and view all the answers

Proteins embedded in the cell membrane can serve as receptors for signaling molecules. What is the immediate consequence of a signaling molecule binding to its receptor?

<p>The receptor protein changes shape. (C)</p> Signup and view all the answers

How do membrane proteins contribute to cell identity?

<p>By marking the cell as 'self' and enabling tissue recognition (B)</p> Signup and view all the answers

Enzymes facilitate biochemical reactions by lowering activation energy. What property of enzymes ensures that they catalyze only specific reactions?

<p>Their specific binding to one or two substrates (B)</p> Signup and view all the answers

Cholesterol is a component of animal cell membranes. What role does it play in maintaining membrane stability and fluidity?

<p>It reduces membrane fluidity and maintains stability. (B)</p> Signup and view all the answers

Which statement accurately describes the arrangement and properties of phospholipids in the cell membrane?

<p>Hydrophobic tails face each other, creating a nonpolar region that restricts the movement of polar molecules. (C)</p> Signup and view all the answers

How does the binding of a signaling molecule to a receptor protein typically initiate a cellular response?

<p>By triggering a conformational change in the receptor protein. (C)</p> Signup and view all the answers

What is the role of a channel protein in the cell membrane?

<p>To provide an opening or pore through which specific molecules can diffuse across the membrane. (C)</p> Signup and view all the answers

How do glycoproteins and glycolipids contribute to a cell's ability to interact with its environment?

<p>By allowing the cell to be recognized by other cells, such as in tissue recognition. (D)</p> Signup and view all the answers

How does the fluidity of the phospholipid bilayer affects the function of the cell membrane?

<p>It allows membrane proteins to move and interact, aiding processes like signaling and transport. (D)</p> Signup and view all the answers

What is the role of membrane proteins in intercellular joinings?

<p>They form tight junctions and plasmodesmata to join cells and enable communication. (A)</p> Signup and view all the answers

Flashcards

Energy Source

Organisms need energy to power metabolic processes.

Liquid Water

Essential for biochemical reactions and cellular transport in organisms.

Chemical Building Blocks

Elements like carbon, oxygen, nitrogen, and hydrogen are essential for life.

Stable Environmental Conditions

Factors like temperature, pressure, and pH that organisms require to survive.

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MRS GREN

A mnemonic for the seven characteristics of living things: Movement, Respiration, Sensitivity, Growth, Reproduction, Excretion, Nutrition.

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Cell Theory

All organisms are composed of cells; cells are the basic unit of life; all cells come from pre-existing cells.

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Prokaryotes

First living organisms without a nucleus or membrane-bound organelles, e.g., bacteria.

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Eukaryotes

Cells with a distinct nucleus and membrane-bound organelles, including animal and plant cells.

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Capsule

A protective layer found in prokaryotic cells, made of polysaccharides.

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Ribosomes

Cell structures that synthesize proteins; found in both prokaryotic and eukaryotic cells.

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Surface Area to Volume Ratio

A calculation important for cellular function; affects how cells exchange materials.

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Nucleus

The membrane-bound organelle in eukaryotic cells that contains DNA.

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Anton van Leeuwenhoek

Invented the microscope and discovered bacteria, calling them 'animalcules'.

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Surface Area of a Cube

Calculated using the formula SA = 6L^2, where L is the length of a side.

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Volume of a Cube

Calculated using the formula V = L^3, representing the space inside the cube.

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Decrease in SA:V Ratio

As objects increase in size, their surface area grows slower than their volume, leading to a lower ratio.

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Metabolic Needs and Cell Size

As a cell's volume increases, its metabolic requirements grow faster than its ability to transport materials.

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Transport Systems in Larger Organisms

Larger organisms often develop transport systems like circulatory systems to manage nutrient and waste movement.

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Single-Celled Organisms

Rely on high SA:V ratios to efficiently absorb resources and expel waste.

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Human Exchange Surfaces

Humans develop specialized surfaces to increase SA:V ratios for effective exchange, unlike smaller organisms.

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Cell Size Limitation

Larger cells move nutrients and wastes slower than smaller cells.

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Microvilli Function

Microvilli increase surface area for nutrient absorption in the small intestine.

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Endosymbiont

A cell that lives inside another cell, often cooperatively.

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Obligate Endosymbiont

An organelle that cannot survive independently of the host cell.

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Mitochondria

Organelle responsible for ATP production through cellular respiration.

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Endoplasmic Reticulum (ER)

Network of membranes for protein processing and lipid synthesis.

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Golgi Apparatus

Processes and packages proteins for secretion from the cell.

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Lysosomes

Spherical organelles containing digestive enzymes for breaking down waste.

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Cytoskeleton

A network providing structural support, shape, and movement in eukaryotic cells.

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Phospholipid Bilayer

A double layer of phospholipids forming the foundational structure of the cell membrane.

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Roles of Cell Membrane Proteins

Proteins in the membrane facilitate transport, signaling, and structure.

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Cholesterol in Membrane

Helps maintain fluidity and stability in the cell membrane.

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Cell Identity

Proteins on the cell surface that help recognize self from non-self.

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Cytosol (Cytoplasm)

The jelly-like substance within the cell where organelles reside.

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Plasma Membrane

A selectively permeable barrier controlling what enters and exits the cell.

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Endoplasmic Reticulum

A network of membranes involved in protein and lipid synthesis.

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The Three Tenets of Cell Theory

All organisms are composed of one or more cells; the cell is the basic unit of life; and all cells come from pre-existing cells.

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Temperature and Diffusion Rate

The measure of molecular movement. Higher temp = faster diffusion.

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Particle Size and Diffusion

Smaller particles diffuse through membranes more quickly.

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Facilitated Diffusion

Molecules move using protein transporters (channels or carriers).

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Channel Proteins

Proteins that don't change shape, allowing charged/polar molecules to diffuse.

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Carrier Proteins

Proteins change shape to transport hydrophilic, uncharged substances.

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Integral Membrane Proteins

Proteins embedded within the phospholipid bilayer, often spanning the entire membrane.

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Transport Proteins

Allow hydrophilic substances to cross the membrane using channel or carrier proteins.

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Receptor Proteins

Bind signaling molecules to alter cell activity.

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Cell Size vs. Transport Rate

The rate of movement of nutrients and wastes decreases as cell size increases.

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Intestinal Microvilli

Small intestine cells increase surface area for nutrient absorption via membrane folding.

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Ribosome Function

Uses mRNA to synthesize amino acids and proteins.

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Nucleus Function

Spherical organelle that houses genetic material (DNA) and controls cell activities.

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Mitochondria Function

Produces ATP through cellular respiration.

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Endoplasmic Reticulum (ER) Function

Processes and transports proteins plus synthesizes lipids.

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Golgi Apparatus Function

Packages proteins into vesicles for transport.

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Lysosome Function

Breaks down excess macromolecules and non-functioning organelles.

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Peroxisome Function

Breaks down toxic substances & contains catalase to degrade hydrogen peroxide.

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Cytoskeleton Function

Provides cell support, shape, and mobility through microtubules, intermediate filaments, and microfilaments.

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Microtubule Function

Moves materials within cells and forms cilia and flagella.

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Passive transport

Moves molecules across the cell membrane down their concentration gradient without energy.

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Energy requirement

The capacity to do work that powers metabolic processes.

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Water requirement

Necessary for biochemical reactions, dissolving chemicals, and transport within organisms.

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Building blocks requirement

Elements like carbon, oxygen, nitrogen, and hydrogen needed to build biological molecules.

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Stable environment need

Conditions like temperature, pressure, and pH must be within tolerable ranges for survival.

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Life Attributes

Movement, Respiration, Sensitivity, Growth, Reproduction, Excretion, Nutrition, and DNA.

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Deoxyribonucleic Acid (DNA)

Double-stranded helix containing genetic information.

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Cell

Basic unit of life; all organisms are made of one or more.

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Cellular Origin

All cells arise from pre-existing cells.

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Prokaryotic Cells

Organisms lacking a nucleus or other membrane-bound organelles.

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Nucleoid

Region in prokaryotes where DNA is located.

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Capsule (Cell)

Outer layer of prokaryotes, made of polysaccharides.

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Cell Wall (Prokaryotic)

Protective layer in prokaryotes made of peptidoglycan.

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Plasmids

Smaller, circular DNA fragments in prokaryotes.

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Eukaryotic Cells

Cells containing a nucleus and membrane-bound organelles.

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Cell Shapes

Variety reflects functional diversity.

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SA:V Ratio

Ratio between the surface area and volume of a cell.

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SA:V Importance

The relationship between the two in cells affects the ability to exchange materials.

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Microvilli

Extensive folds in the small intestine increasing the surface area.

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Robert Hooke

Coined the term 'cell' after observing dead cork cells.

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Osmosis

The movement of water across a semi-permeable membrane from an area of lower solute concentration to higher solute concentration.

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Hypotonic Environment

Concentration is lower outside the cell than inside, water moves into the cell.

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Hypertonic Environment

Concentration is higher outside the cell than inside, thus water moves out of the cell.

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Hydrophobic Tails

Fatty acid chains are non-polar, and repel water.

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Hydrophilic Heads

Phosphate containing heads are polar and attract water.

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Integral Proteins

Proteins embedded within the phospholipid bilayer.

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Transmembrane Proteins

A type of integral protein that spans the entire plasma membrane

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Glycoproteins

Proteins with carbohydrate groups attached.

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Peripheral Proteins

Anchored to the exterior of the plasma membrane or associated with integral proteins.

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Transport (Cell Membrane Role)

Proteins facilitate the movement of hydrophilic molecules across the membrane.

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Reception (Cell Membrane Role)

Proteins receive and bind to signaling molecules, triggering a response.

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Anchorage (Cell Membrane Role)

Proteins connecting cytoskeleton to the extracellular matrix.

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Cell Identity (Cell Membrane Role)

Proteins (glycoproteins, antigens) marking cells as 'self'.

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Peroxisomes

Organelles involved in cellular metabolism and detoxification, containing enzymes like catalase to break down hydrogen peroxide.

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Microtubules

Hollow tubes that move materials within cells and form cilia and flagella.

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Microfilaments

Responsible for most cell movement, consists of actin.

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Cilia

Hair-like structures used for movement; many per cell.

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Flagella

Tail-like structure used for movement; usually one per cell.

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Active Transport

The movement of molecules or ions across a cell membrane against their concentration gradient, requiring energy (ATP).

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Study Notes

  • Cells need an energy source, liquid water, chemical building blocks (carbon, oxygen, nitrogen, hydrogen), and stable environmental conditions to exist.
  • Stable environmental conditions include stable pressure, temperature, pH, light intensity, and salinity

Cell Attributes

  • All living things share the attributes, Movement, Respiration (converting glucose into ATP), Sensitivity to stimuli to the environment, Growth, Reproduction (sexual or asexual), Excretion, Nutrition (intake of food), and DNA.

Cell Theory (1839)

  • Developed by Theodor Schwann and Matthias Schleiden
  • All organisms are composed of one or more cells
  • The cell is the basic unit of structure and organisation in organisms
  • All cells come from pre-existing cells

Early Microscopy

  • Anton van Leeuwenhoek invented his own microscope and saw bacteria from dental scraping, calling them "bacteria animalcules".
  • Robert Hook invented the name "The cell."
  • Robert Hook only saw dead cells and named cells from looking at prison cells
  • Robert Remack proved that cells come from pre-existing cells.
  • Matthias Schleiden believed that all cells did not come from other cells

Prokaryotes

  • Prokaryotes were the first living organisms on earth.
  • Prokaryotes lack a nuclear membrane, so they don't have a distinct nucleus.
  • Prokaryotes lack membrane-bound organelles and do have ribosomes

Prokaryotic Cell Makeup

  • Capsule made of polysaccharides
  • Cell wall made of peptidoglycan
  • Cell (plasma) controls what enters and leaves the cell
  • Large, circular DNA
  • Ribosomes synthesise proteins
  • Plasmids are smaller pieces of DNA
  • Cytosol contains everything in the cell

Eukaryotes

  • Eukaryotes have a nuclear membrane (distinct nucleus) and membrane-bound organelles.
  • Eukaryotes are larger than prokaryotic cells.
  • Examples of eukaryotes are animal, plant, protist, and fungal cells.
  • Eukaryotic DNA is found in the nucleus

Cell Shapes

  • Cells come in a variety of shapes that reflect various functions
  • Some cells, like white blood cells, amoebas, and cancer cells, can change shapes

Surface Area to Volume Ratio

  • The surface area to volume ratio (SA:V) measures the balance between surface area and volume.
  • The surface area of a cube is calculated using the formula: SA = 6L^2, wherein L = the length of one side.
  • The volume of a cube is calculated using the formula: V = L^3.
  • As a cube increases in size, volume enlarges faster than the surface area.
  • As cells increase in size (larger cytoplasm), surface area and volume increase at unequal rates.
  • Internal volume expands faster than the plasma membrane area; therefore cell growth leads to the relative decrease of its plasma membrane. A small SA:V ratio is the result of this

SA:V Ratio

  • Single-celled organisms continuously perform chemical reactions, absorb resources such as Oxygen, Glucose and Amino acids, and get rid of waste such as Co^2 .
  • Surface area : Volume decreases as objects get larger; bacteria have a high SA:V ratio and can rely on diffusion

Diffusion in Larger Organisms

  • Humans cannot rely on diffusion due to a low SA:V ratio, and they have specialized exchange surfaces to increase this ratio.
  • As organisms grow larger, the distance molecules must diffuse increases massively, which is why larger organisms use transport systems, such as the circulatory system

Metabolic Needs

  • As cell volume increases, metabolic needs increase, requiring increased inputs and outputs across the plasma membrane. Material increases in proportion to the cell's surface area.
  • As cell volume increases, metabolic needs increase faster than cell's ability to transport materials. This explains why active metabolic cells are so small.
  • The rate at which nutrients enter/wastes leave is generally inverse to cell size (measured in cytoplasm); the larger the cell, the slower the nutrient/waste movement.
  • Cells absorbing digested nutrients (small intestine) compensate for decreasing size
  • Surface area increase with minimal volume increase by plasma folding on the gut lumen creating microvilli.

Organelles

  • Cytosol (cytoplasm)
  • Plasma membrane
  • Nucleus
  • Mitochondria
  • Ribosome
  • Golgi apparatus
  • Endoplasmic reticulum
  • Deoxyribonucleic acid - DNA

Obligate Organelle features

  • All plant and animal cells contain a nucleus/nuclear membrane, nucleoles, plasma membrane, ribosomes and peroxisomes, cytoskeleton, cytosol, endoplasmic rectiulum, mitochondria, and golgi apparatus

Proteins within cells

  • Proteins include haemoglobin, actin and myosin (contractile proteins), insulin and lipase, and antibodies (white blood cells)

Nucleus

  • The nucleus houses DNA is enclosed within double walled membrane
  • The nucleus controls DNA replication during cell division, initiates gene expression and controls metabolic activities

Nucleolus

  • The nucleolus is composed of RNA and not enclosed within a membrane.It produces RNA

Mitochondria

  • Mitochondria are for energy production and produce ATP in cellular respiration
  • Mitochondria are visible with an electron microscope only; they are a double membrane organelle.
  • The more active the cell, the more mitochondria present.
  • Mature red blood cells lack mitochondria.

Golgi apparatus

  • The Golgi apparatus is a layered structure where proteins from the rough ER get transferred, where proteins are packaged into secretary vesicles

Lysosomes

  • Lysosomes are spherical shaped and contain about 50 digestive enzymes
  • Lysosomes digest macromolecules within a cell, and perform autophagy (the breakdown of non-functioning cell organelles)

Peroxisomes

  • Peroxisomes are used for cellular metabolism and the oxidization of fatty acids
  • They break down toxic substances, contain many enzymes, break down hydrogen peroxide via catalysis, and adheres to this equation 2H2O2 (I) → 2H2O (I) + O2 (g)

Cytoskeleton

  • The cytoskeleton is a 3D frame work of eukaryotic cells with 3 components
  • Functions include: supplying support and strength for the cell, maintaining cell shape and cell mobility, moving cell organelles.
  • The cytoskeleton is used for moving chromosomes during cell divisions

Cell membrane

  • Some unicellular eukaryotes depend on cilia and flagella to move.
  • Flagella are generally singular, and look like a tail.
  • However, cillia are shorter and more numerous.
  • Functions include: Cell shape, cell mobility, movement of cell organelles, and moving chromosomes during cell divisions 3 components

Cell Membrane features

  • The cell membrane is an active and selective barrier that receives messages from outside and transports materials between the intracellular and extra cellular environment
  • If a cell doesn't display the correct molecules, an immune response takes place and the cell dies

Plasma Membrane

  • The plasma membrane has 2 main components.
  • A type of molecule crossing can be determined if it is hydrophilic or hydrophobic, and also by molecule size and concentration gradient

Phospholipid Bilayer

  • Consists of two layers with hydrophobic tails facing each other and consists of two fatty acid chains joined to a hydrophilic phosphate The head faces the cytosol.
  • At a normal body temperature the proteins are viscous fluids and are fluid, flexible, soft, able to move freely enabling red blood cells to squeeze through capillaries and enabling cells to change shape

Plasma Membrane - proteins

  • Proteins can be embedded in the bilayer and move freely within the bilayer.
  • Proteins are either Integral or Peripheral
    • Integral are Embedded in the phospholipid bilayer and span the width of the plasma membrane. They are transmembrane proteins.
    • If carbohydrate groups like sugars are attached to the exposed part of these proteins they are Glycoproteins which can be anchored to the exterior of the plasma membrane by bonding to lipids
      • If proteins are indirectly associated with the plasma membrane, its through interactions with integral proteins in the membrane

Cell Membrane and Proteins

  • Transport: Trans-membrane proteins allow movement of the hydrophilic substances across the phospholipid bilayer; they can travel through:
    • Channel proteins: Open to all molecules to diffuse in to and out of the cell, and These substance are usually small and charged like ions
    • Carrier proteins: allow the movement for larger molecules
    • Reception
      • The cell may uses receptors for signalling molecules which are peptide or amino acid-based molecules. The shape is altered when the singal reachs the protiens
    • Anchorage
      • Proteins connect the intracellular cytoskeleton to the extracellular matrix
      • Proteins connect the intracellular cytoskeleton to the extracellular matrix. Proteins connect to the cell via collagen fibres and peptidoglycan filaments that have been excreted by cells
    • Cell identity
      • Proteins mark the as belonging to self.
      • They are Glycoproteins, Antigens, and Cell identity tags can signal other cells
      • In mammals that let immune System to identify the cells as self via marker proteins from the blood cells
      • Glycolipids on the plasma membranes play a role in tissue recognition
  • Intercellular joinings
    • Proteins connect to hold the tissues together
    • They join cells together and facilitate communication between cells. Allowing tissues to have efficient functioning
  • Enzymatic activity
    • Enymes are Proteins that catalyse reactions by lowering activation energy and bind the substrates and weaken the bonds to initiate the reaction
    • The enzyme's specificity can only bind to one and/or two substrates and aren't altered in the prosess
    • Facilitating other biochemical pathways, such as the production of ATP

The cell also uses other compounds

  • Cholesterol maintains membrane stability and fluidity, whilst reducing membrane fluidity
  • Carbohydrates are surface markers allowing identifiers via cytoplasm
    • They are used in Glycoproteins for cell identity, or for inter cellular joinings to attach cells to the glycollipids

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Test your knowledge of the fundamental attributes of life, cellular structures, and cell theory. Explore energy requirements, cellular adaptations, and prokaryotic vs. eukaryotic cells. Match scientists with their contributions to cell theory.

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