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Questions and Answers
The functions of the extracellular matrix include:
The functions of the extracellular matrix include:
The major families of cell surface adhesion molecules include:
The major families of cell surface adhesion molecules include:
Cadherin cellular adhesion molecules promote:
Cadherin cellular adhesion molecules promote:
Desmosomes:
Desmosomes:
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Which of the following statements best describes the difference between low-affinity integrins and high-affinity integrins?
Which of the following statements best describes the difference between low-affinity integrins and high-affinity integrins?
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Vertebrate gap junctions are composed of:
Vertebrate gap junctions are composed of:
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A tight junction is made up of which of the following proteins?
A tight junction is made up of which of the following proteins?
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Cellular responses to adhesion receptor signaling do NOT include:
Cellular responses to adhesion receptor signaling do NOT include:
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Which of the following is the term used to describe a thin, sheet-like meshwork of extracellular matrix components that can be found in epithelial cells?
Which of the following is the term used to describe a thin, sheet-like meshwork of extracellular matrix components that can be found in epithelial cells?
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Basal lamina include all of the following, except:
Basal lamina include all of the following, except:
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Which one of the following is NOT a property of perlecan?
Which one of the following is NOT a property of perlecan?
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The collagen triple-helix domain is NOT:
The collagen triple-helix domain is NOT:
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Proteoglycans are:
Proteoglycans are:
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Syndecans are cell-surface proteoglycans that:
Syndecans are cell-surface proteoglycans that:
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Biological roles of proteoglycans and hyaluronan include all of the following, except:
Biological roles of proteoglycans and hyaluronan include all of the following, except:
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Which extracellular matrix component is expressed in a cell-specific manner and binds to the tripeptide sequence Arg-Gly-Asp?
Which extracellular matrix component is expressed in a cell-specific manner and binds to the tripeptide sequence Arg-Gly-Asp?
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Polymerization of collagen into large collagen fibers occurs:
Polymerization of collagen into large collagen fibers occurs:
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Hydroxyproline is important in the formation of staple collagen polymers within cells. The formation of hydroxyproline requires:
Hydroxyproline is important in the formation of staple collagen polymers within cells. The formation of hydroxyproline requires:
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Which of the following is NOT true regarding matrix metalloproteases?
Which of the following is NOT true regarding matrix metalloproteases?
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Heparan sulfate, an example of a(n) ______ , aids in the activation of ______ .
Heparan sulfate, an example of a(n) ______ , aids in the activation of ______ .
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NCAMs, a group of cell-adhesion proteins belonging to the Ig superfamily:
NCAMs, a group of cell-adhesion proteins belonging to the Ig superfamily:
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Dystroglycan is a large glycoprotein that binds to dystrophin in muscle cells. It is also present in other cells and can also bind to:
Dystroglycan is a large glycoprotein that binds to dystrophin in muscle cells. It is also present in other cells and can also bind to:
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Which of the following best describes the structure of integrins?
Which of the following best describes the structure of integrins?
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What signal is released by endothelial cells to recruit circulating leukocytes?
What signal is released by endothelial cells to recruit circulating leukocytes?
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People with a defect in the synthesis of the integrin β2 subunit exhibit reduced:
People with a defect in the synthesis of the integrin β2 subunit exhibit reduced:
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What effect might an injection of RGD peptide have on tumor cells moving through the blood/lymph system?
What effect might an injection of RGD peptide have on tumor cells moving through the blood/lymph system?
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As fibroblasts form a three-dimensional structure in contact with the ECM, the cells bound to ECM:
As fibroblasts form a three-dimensional structure in contact with the ECM, the cells bound to ECM:
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Pectins and hyaluronic acid are both:
Pectins and hyaluronic acid are both:
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Which of these is NOT a component of plant cell walls?
Which of these is NOT a component of plant cell walls?
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Study Notes
Extracellular Matrix Functions
- Supports cell differentiation
- Induces morphogenesis
- Binds growth hormones
Cell Surface Adhesion Molecules
- Major families include cadherins, selectins, integrins, and the immunoglobulin superfamily
Sponge Cell Aggregation
- Cells from the same species aggregate
- Cells from different species do not adhere
- Calcium-dependent interactions
- Homotypic proteoglycan aggregation factors
- Bind to surface receptors within the extracellular matrix
Cadherin Function
- Cell-specific homophilic interactions
Desmosomes Structure
- Associated with actin filaments on the cytoplasmic side
- Contains desmoglein and desmocollin transmembrane proteins
Integrins: Low vs High Affinity
- Integrins exist in low-affinity (bent) and high-affinity (straight) conformations
- Integrin dissociation can shift from low to high-affinity state
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Description
Explore the intricate functions of the extracellular matrix and cell surface adhesion molecules in this detailed quiz. Delve into topics like cadherins, desmosomes, and integrins, and their roles in cell differentiation and aggregation. Perfect for students of cell biology looking to strengthen their understanding.
