Funbio 5
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Questions and Answers

What distinguishes Rough Endoplasmic Reticulum (RER) from Smooth Endoplasmic Reticulum (SER)?

RER is studded with ribosomes, while SER is free of attached ribosomes.

What are the two types of proteins synthesized by the Rough Endoplasmic Reticulum?

Water-soluble proteins and prospective transmembrane proteins.

Name two examples of proteins produced by the Rough Endoplasmic Reticulum.

Digestive enzymes and hormones.

How does the Rough Endoplasmic Reticulum contribute to protein processing?

<p>It performs post-translational processing, which includes modifications like protein folding.</p> Signup and view all the answers

Identify one key function of the Smooth Endoplasmic Reticulum.

<p>Lipid synthesis.</p> Signup and view all the answers

In which types of cells is the Smooth Endoplasmic Reticulum particularly well developed?

<p>Liver cells and cells that secrete steroid hormones, such as adrenal cortex cells.</p> Signup and view all the answers

Explain the role of the Rough Endoplasmic Reticulum in protein transport within the cell.

<p>The RER transports synthesized proteins to different parts of the cell, particularly to the Golgi Apparatus.</p> Signup and view all the answers

What happens to proteins synthesized in the Rough Endoplasmic Reticulum after they accumulate?

<p>They may be stored in cisternae and transported to the plasma membrane when needed.</p> Signup and view all the answers

What is the primary appearance of the endoplasmic reticulum in a cell?

<p>The endoplasmic reticulum appears as an elaborate membrane system that may occupy up to 50% of the total membrane surface of animal cells.</p> Signup and view all the answers

What role does the smooth endoplasmic reticulum play in cellular functions?

<p>The smooth ER is involved in lipid production and detoxification processes.</p> Signup and view all the answers

How is rough endoplasmic reticulum structurally different from smooth ER?

<p>Rough ER is studded with ribosomes on its cytoplasmic surface, giving it a 'rough' appearance.</p> Signup and view all the answers

What specialized form of endoplasmic reticulum is known for storing calcium ions?

<p>The specialized form is called the sarcoplasmic reticulum.</p> Signup and view all the answers

List the four major functions of the Golgi apparatus.

<p>The four major functions include modification, sorting, packaging of proteins, and the production of primary lysosomes.</p> Signup and view all the answers

What is the structure of peroxisomes and their primary function?

<p>Peroxisomes are membrane-bound organelles containing enzymes that oxidize fatty acids and amino acids.</p> Signup and view all the answers

What types of granules are present in certain classes of cells and what are they called?

<p>Certain cells contain secretory and zymogen granules.</p> Signup and view all the answers

In what way does the endoplasmic reticulum contribute to the nuclear envelope after cell division?

<p>After cell division, the nuclear envelope is partially reformed from remnants of the endoplasmic reticulum.</p> Signup and view all the answers

What is the primary role of the Golgi apparatus in a cell?

<p>The Golgi apparatus processes, modifies, sorts, and packages proteins for transport to their destinations.</p> Signup and view all the answers

Describe the structural arrangement of cisternae in the Golgi apparatus.

<p>Cisternae are arranged in a parallel stack, typically varying in number from 3 to 7, with spaces between them called lumen.</p> Signup and view all the answers

What are the two main faces of the Golgi apparatus and their functions?

<p>The cis face receives materials from the ER, while the trans face releases processed materials to the cell surface or other destinations.</p> Signup and view all the answers

How does the Golgi apparatus contribute to muscle contraction in cardiac muscle cells?

<p>The Golgi apparatus plays a role in processing proteins that are essential for excitation-contraction coupling in muscle cells.</p> Signup and view all the answers

In plant cells, where is the Golgi apparatus typically found?

<p>In plant cells, Golgi bodies are dispersed throughout the cytoplasm.</p> Signup and view all the answers

What types of products does the Golgi apparatus process and package?

<p>The Golgi apparatus processes proteins, glycoproteins, and mucopolysaccharides.</p> Signup and view all the answers

Explain the role of vesicles associated with the Golgi apparatus.

<p>Vesicles transport materials in and out of the Golgi apparatus, entering from the cis face and exiting from the trans face.</p> Signup and view all the answers

Who discovered the Golgi apparatus and when?

<p>The Golgi apparatus was discovered by Camillo Golgi in 1898.</p> Signup and view all the answers

What is the primary role of lysosomes in animal cells?

<p>Lysosomes are responsible for intracellular digestion and the removal of unwanted elements such as pathogens and debris.</p> Signup and view all the answers

How are primary lysosomes formed?

<p>Primary lysosomes bud off from the Golgi apparatus.</p> Signup and view all the answers

What distinguishes secondary lysosomes from primary lysosomes?

<p>Secondary lysosomes contain material that is to be digested, resulting from the fusion of primary lysosomes with phagosomes or endosomes.</p> Signup and view all the answers

What is the optimal pH for lysosomal enzymes to function?

<p>The optimum activity of lysosomal enzymes occurs at a pH of 5.0.</p> Signup and view all the answers

Describe the structure of peroxisomes.

<p>Peroxisomes are rounded organelles that are bound by a single membrane and contain a granular matrix with occasional crystal-like cores.</p> Signup and view all the answers

What is one of the key contents of lysosomes that facilitates digestion?

<p>Lysosomes contain powerful hydrolytic enzymes synthesized in the rough endoplasmic reticulum.</p> Signup and view all the answers

What role does the Golgi apparatus play in the functioning of lysosomes?

<p>The Golgi apparatus is involved in the synthesis and post-translational modification of lysosomal enzymes, marking proteins for dispersion into lysosomes.</p> Signup and view all the answers

What happens to undigested materials within lysosomes?

<p>Undigested or indigestible materials accumulate as residual bodies within lysosomes.</p> Signup and view all the answers

What role does calcium ion release from the sarcoplasmic reticulum play in muscle contraction?

<p>It initiates the contraction process by triggering excitation-contraction coupling.</p> Signup and view all the answers

Explain the significance of glucose-6-phosphatase in the context of glycogenolysis.

<p>Glucose-6-phosphatase converts glucose-6-phosphate to glucose, facilitating the release of glucose into the bloodstream during glycogenolysis.</p> Signup and view all the answers

Contrast the functions of the smooth endoplasmic reticulum and the sarcoplasmic reticulum.

<p>The smooth endoplasmic reticulum is involved in lipid production and detoxification, while the sarcoplasmic reticulum is specialized for calcium storage and release in muscle cells.</p> Signup and view all the answers

What processes does the smooth endoplasmic reticulum conduct in the liver cells, particularly in response to chemical insults?

<p>It increases the activity of detoxification enzymes and may proliferate to enhance these functions.</p> Signup and view all the answers

Is the statement 'Smooth endoplasmic reticulum has ribosomes' true or false? Justify your answer.

<p>False, the smooth endoplasmic reticulum does not have ribosomes; ribosomes are found on the rough endoplasmic reticulum.</p> Signup and view all the answers

What is the main function of peroxisomes in the cell?

<p>Peroxisomes function to break down compounds using oxidative enzymes and remove H+ ions, producing hydrogen peroxide as a by-product.</p> Signup and view all the answers

Describe the reaction that occurs during the function of peroxisomes.

<p>The reaction is: $RH2 + O2 \rightarrow R + H2O2$, where organic substrates are oxidized and hydrogen peroxide is produced.</p> Signup and view all the answers

How is hydrogen peroxide detoxified in peroxisomes?

<p>Hydrogen peroxide is detoxified by the enzyme catalase, which uses it to oxidize various substances.</p> Signup and view all the answers

What is Zellweger syndrome and its connection to peroxisomes?

<p>Zellweger syndrome is a defect in peroxisomes that leads to severe abnormalities in brain, liver, and kidneys, resulting in infant mortality.</p> Signup and view all the answers

Where do secretory granules originate in the cell?

<p>Secretory granules originate from the trans-face of the Golgi Apparatus.</p> Signup and view all the answers

What triggers the release of insulin from secretory granules?

<p>The release of insulin is triggered by elevated glucose levels in the blood.</p> Signup and view all the answers

What is the role of exocytosis in the function of secretory granules?

<p>Exocytosis allows secretory granules to fuse with the plasma membrane and release their contents outside the cell.</p> Signup and view all the answers

What types of substances can be oxidized by catalase in peroxisomes?

<p>Catalase can oxidize a variety of substances, including alcohol, phenols, and formaldehyde.</p> Signup and view all the answers

Study Notes

Endoplasmic Reticulum (ER)

  • Two types of ER: rough ER and smooth ER
  • Both are interconnected membrane systems within cells
  • Rough ER is studded with ribosomes and involved in protein synthesis
  • Smooth ER is lacking ribosomes and functions in lipid production, steroid synthesis, and detoxification

Rough ER

  • Abundant in cells actively synthesizing proteins
  • Ribosomes on the rough ER surface attach to and translate mRNA
  • Synthesizes proteins destined for various locations: cell membrane, secretion, lysosomes, etc.
  • Involved in post-translational protein modification (folding, etc)

Smooth ER

  • Abundant in cells involved in lipid metabolism and steroid production (e.g., liver, adrenal cortex cells)
  • Functions in lipid synthesis, steroid hormone production, carbohydrate metabolism, detoxification (drug breakdown), and calcium ion storage (sarcoplasmic reticulum in muscle cells)
  • Plays critical roles in different types of cells and tissues

Golgi Apparatus (or Golgi complex)

  • Found in all eukaryotic cells

  • Has a complex structure consisting of flattened sacs called cisternae

  • Plays a crucial role in modifying, sorting, and packaging proteins for transport to their final destinations

  • Modified by attaching sugars, lipids, etc

  • Four major functions:

    • Processing newly synthesized secretory products (proteins and glycoproteins)
    • Acts as a center for redistribution of cell membranes (lipid transport)
    • Production of primary lysosomes
    • Involved in carbohydrate synthesis

Membrane-Bound Vesicles and Secretory Granules

  • These granules contain specific contents and have different structures and purposes
  • Lysosomes:
    • Found in animal cells, contain enzymes for intracellular digestion
    • Digestion of various cellular components or substances
    • Formed from the Golgi apparatus
  • Peroxisomes:
    • Contain enzymes for oxidative reactions
    • Key role in removing hydrogen peroxide and breaking down fatty acids
  • Secretory Granules:
    • Store and release specific substances (e.g., hormones)
    • Release content by exocytosis

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Description

This quiz explores the differences and functions of Rough and Smooth Endoplasmic Reticulum. Discover the key roles they play in protein synthesis and processing, and learn about their structural distinctions. Test your understanding of cellular functions related to the endoplasmic reticulum.

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