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Questions and Answers
What is the primary role of the cell membrane?
What is the primary role of the cell membrane?
Which type of microscope is most suitable for viewing the internal structures of cells?
Which type of microscope is most suitable for viewing the internal structures of cells?
What determines the shape of a cell?
What determines the shape of a cell?
Which of the following is NOT a characteristic of eukaryotic cells?
Which of the following is NOT a characteristic of eukaryotic cells?
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What is one of the largest cells in the human body?
What is one of the largest cells in the human body?
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What is the primary function of cholesterol molecules in the cell membrane?
What is the primary function of cholesterol molecules in the cell membrane?
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Which type of protein extends across the lipid bilayer and assists with the transport of ions and molecules?
Which type of protein extends across the lipid bilayer and assists with the transport of ions and molecules?
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Which type of heads in the lipid bilayer are characterized by their affinity to aqueous solutions?
Which type of heads in the lipid bilayer are characterized by their affinity to aqueous solutions?
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What role does the carbohydrate component, such as glycoproteins and glycolipids, play in the cell membrane?
What role does the carbohydrate component, such as glycoproteins and glycolipids, play in the cell membrane?
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How are the tails of molecules oriented in the lipid bilayer?
How are the tails of molecules oriented in the lipid bilayer?
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What is the primary function of nucleoplasm?
What is the primary function of nucleoplasm?
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Which of the following correctly describes the nucleolus?
Which of the following correctly describes the nucleolus?
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Chromatin is composed primarily of which two substances?
Chromatin is composed primarily of which two substances?
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What role do chromosomes play in the cell?
What role do chromosomes play in the cell?
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What is the composition of the nucleoplasm?
What is the composition of the nucleoplasm?
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Which type of tissue involves the differentiation of various cell types into larger structures?
Which type of tissue involves the differentiation of various cell types into larger structures?
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What is one of the main components of tissues?
What is one of the main components of tissues?
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Which type of epithelial tissue is characterized by layers?
Which type of epithelial tissue is characterized by layers?
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What is the primary role of epithelial tissue?
What is the primary role of epithelial tissue?
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Which of the following is NOT a characteristic of epithelial tissue?
Which of the following is NOT a characteristic of epithelial tissue?
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Which type of epithelium is classified as having multiple layers?
Which type of epithelium is classified as having multiple layers?
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What structure found on the apical surface of epithelial cells increases the surface area for absorption?
What structure found on the apical surface of epithelial cells increases the surface area for absorption?
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Epithelial tissue can be classified based on cell shape. Which of the following describes cube-shaped cells?
Epithelial tissue can be classified based on cell shape. Which of the following describes cube-shaped cells?
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Which epithelial tissue type is primarily involved in the filtration of wastes from blood plasma in the kidneys?
Which epithelial tissue type is primarily involved in the filtration of wastes from blood plasma in the kidneys?
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Cilia on epithelial cells serve what primary purpose?
Cilia on epithelial cells serve what primary purpose?
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What is the function of glandular epithelial cells?
What is the function of glandular epithelial cells?
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What feature distinguishes fibrocartilage from hyaline cartilage?
What feature distinguishes fibrocartilage from hyaline cartilage?
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Which type of cartilage is specifically noted for maintaining shape while allowing flexibility?
Which type of cartilage is specifically noted for maintaining shape while allowing flexibility?
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Where is fibrocartilage typically found in the body?
Where is fibrocartilage typically found in the body?
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What characteristic is most associated with the aorta and large arteries?
What characteristic is most associated with the aorta and large arteries?
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What type of connective tissue contains chondrocytes?
What type of connective tissue contains chondrocytes?
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Which type of connective tissue is known for its ability to absorb compression shock?
Which type of connective tissue is known for its ability to absorb compression shock?
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How does elastic cartilage differ from hyaline cartilage?
How does elastic cartilage differ from hyaline cartilage?
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Which connective tissue is primarily responsible for transporting nutrients and oxygen throughout the body?
Which connective tissue is primarily responsible for transporting nutrients and oxygen throughout the body?
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What is the primary function of vasa vasorum?
What is the primary function of vasa vasorum?
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Which part of the lymphatic system is primarily responsible for collecting lymph from the body?
Which part of the lymphatic system is primarily responsible for collecting lymph from the body?
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How do lymphatic capillaries differ from blood capillaries?
How do lymphatic capillaries differ from blood capillaries?
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Which lymphatic structure is responsible for filtering lymph and initiating an immune response?
Which lymphatic structure is responsible for filtering lymph and initiating an immune response?
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What areas of the body does the thoracic duct drain lymph from?
What areas of the body does the thoracic duct drain lymph from?
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What happens to interstitial fluid as it enters the lymphatic system?
What happens to interstitial fluid as it enters the lymphatic system?
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What role does the lymphatic system play in fluid balance in the body?
What role does the lymphatic system play in fluid balance in the body?
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What type of fluid is lymph classified as?
What type of fluid is lymph classified as?
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Study Notes
Introduction to Histology
- Histology is the science that deals with the microscopic structure of cells and tissues.
- The cell is the basic unit of life and the structural and functional unit of all living tissues.
- Robert Hooke (1635-1703) is credited with the discovery of cells.
Types of Microscopes
- Light Microscope (LM): used to view cells and tissues
- Transmission Electron Microscope (TEM): used to view fine details of cells and cell structure, has higher resolution than LM.
Cell Diversity
- Cells in the same organism exhibit enormous diversity in size, shape and internal organization
- Cell shape depends on its function
- The female egg is the largest cell in the human body and is visible without a microscope.
- Most other cells require a microscope for viewing.
Internal Organization
- Prokaryotic Cells: lack membrane-bound organelles, have a nucleoid region, and a cell wall
- Eukaryotic Cells: characterized by membrane-bound organelles including the nucleus.
Prokaryotic Examples
- ONLY Bacteria
- Capsule
- Cell Wall
- Cytoplasmic Membrane
- Ribosomes
- Pili
- Cytoplasm
- Nucleoid
- Flagella
Eukaryotic Cells
- Two kinds: Plant and Animal
Animal Cell Anatomy
- Mitochondria
- Microfilaments
- Lysosomes
- Rough Endoplasmic Reticulum
- Peroxisome
- Centrioles
- Micro Tubules
- Golgi Apparatus
- Cilia
- Smooth Endoplasmic Reticulum
- Nucleus
- Nuclear Pores
- Plasma Membrane
- Nucleolus
- Nuclear Envelope
- Chromatin
Plant Cell Anatomy
- Chloroplast
- Cell Membrane
- Cell wall
- Vacuole
- Golgi apparatus
- Mitochondrion
Cytosol and Cytoplasm
- Cytosol: The "soup" within which the other cell organelles reside and where most of the cellular metabolism occurs.
- Cytoplasm: A collective term for the cytosol plus the organelles suspended within the cytosol.
Organelles
- A. Membranous Organelles
-
- Cell membrane (plasma membrane)
-
- Mitochondria
-
- Endoplasmic reticulum (rough & smooth)
-
- Golgi apparatus
-
- Lysosomes
-
- B. Non-membranous Organelles
-
- Ribosomes
-
- Cytoskeleton
-
Plasma membrane (Cell membrane)
- The boundary of the cell
- Composed of three distinct layers: two layers of fat and one layer of protein.
- Light Microscopy (LM): Difficult to see (H&E)
- Electron Microscopy (EM): Appears as two electron-dense (dark) lines, separated by an electron-lucent (light) one (trilamellar).
Molecular Structure of Cell Membrane
- 1- Lipid Component
- a) Phospholipid molecules
- b) Cholesterol molecules
- 2- Protein Component
- a) Extrinsic (peripheral)
- b) Intrinsic (integral)
- 3-Carbohydrate Component
Functions of Cell Membrane
- Bulk Transport
- a) Endocytosis
-
- Phagocytosis
-
- Pinocytosis
-
- b) Exocytosis
- a) Endocytosis
- Receptor-mediated endocytosis (selective transport)
The Nucleus
- Brain of the cell
- Borderd by a porous membrane - nuclear envelope.
- Contains thin fibers of DNA and protein - chromatin
- Rod Shaped Chromosomes
- Contains a small round nucleolus
- produces ribosomal RNA which makes ribosomes.
Endoplasmic Reticulum
- A complex network of transport channels.
- Two types:
-
- Smooth- ribosome free
- Functions in lipid and steroid hormone synthesis, breakdown of lipid-soluble toxins in liver cells, and control of calcium release in muscle cell contraction
-
- Rough - contains ribosomes and releases newly made protein from the cell.
-
Golgi Apparatus
- A series of flattened sacs that modifie, packages, stores, and transports proteins to cell surface to be secreted.
- Secretions include hormones, enzymes, antibodies, and other molecules.
- Works with endoplasmic reticulum and ribosomes.
Lysosomes
- Recycling Center
- Recycle cellular debris
- Membrane bound organelle containing a variety of enzymes.
- Help digest food particles, nutrients, foreign and dead materials.
Mitochondrion
- Double Membranous
- Size of a bacterium
- Contains its own DNA: mDNA
- Responsible for respiration and energy production in the cell (produces high energy compound ATP)
Cell Diversity in the context of Cell Morphology & Structure
- Cell diversity results from variation in internal structures and specialized functions.
- The differences between cells (e.g., nerve cells, muscle cells, and epithelial cells) are due to the expression of proteins within the respective cellular architecture.
Types of Tissues
- Epithelium (covering) : sheets of cells, closely attached to one another forming a protective barrier
- Connective (support)
- Muscle (movement)
- Nervous (control)
Functions of Epithelial Tissue
- Protection
- Absorption
- Filtration
- Secretion
Classification of Epithelia
- Thickness
- Simple
- Stratified
- Shape
- Squamous
- Cuboidal
- Columnar
Features of Apical Surface of Epithelium
- Microvilli
- Cilia
- Flagella
Features of the Basal Surface of Epithelium
-
Basal Lamina
-
Basement membrane
-
Selective filter
Features of Lateral Surface of Epithelium
- Proteins
- Contour
Cell Junctions
- Desmosomes
- Tight Junctions
- Gap junction
Types of Connective Tissue
- Loose Connective Tissue
- Dense Connective Tissue
- Cartilage
- Bone
- Blood
Other Tissues
- The Nucleus
- Nerve Cell & Skin
- Nervous System
- Glial Cells (Neuroglia)
- Muscle Tissue
- Tendons & Ligaments
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Description
Test your knowledge on key concepts of cell biology, including the structure and function of cell membranes, types of microscopes, and characteristics of eukaryotic cells. This quiz covers important details about cellular components and their roles in maintaining cell integrity and function.