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Questions and Answers
What is the purpose of INR calculation?
What is the purpose of INR calculation?
- To measure platelet count
- To guide heparin dosing
- To standardize PT results (correct)
- To measure platelet function
Which of the following correlates with an ACT test?
Which of the following correlates with an ACT test?
- Provides information on function of the extrinsic pathway
- Normal value for standard patient is > 400 seconds
- Guides warfarin dosing
- More accurate than PTT if using a large dose of heparin (correct)
When should the ACT be measured after going on CPB?
When should the ACT be measured after going on CPB?
- Every 45 minutes after going on CPB
- 3 minutes after going on CPB (correct)
- 30 seconds after going on CPB
- 60 seconds after going on CPB
What is the target INR for patients on warfarin?
What is the target INR for patients on warfarin?
Which of the following is correct regarding a Platelet Count?
Which of the following is correct regarding a Platelet Count?
What is the primary role of platelets in hemostasis?
What is the primary role of platelets in hemostasis?
Which of the following best describes the initial response to blood vessel damage in hemostasis?
Which of the following best describes the initial response to blood vessel damage in hemostasis?
What is the main function of the fibrinolytic system in hemostasis?
What is the main function of the fibrinolytic system in hemostasis?
Which of the following involves the activation of tissue factor (TF) in hemostasis?
Which of the following involves the activation of tissue factor (TF) in hemostasis?
What happens when there is no injury to blood vessels in terms of hemostasis?
What happens when there is no injury to blood vessels in terms of hemostasis?
In which of the following vessels are hemostatic mechanisms less effective in dealing with bleeding?
In which of the following vessels are hemostatic mechanisms less effective in dealing with bleeding?
What is the main role of the cell-based prothrombinase complex?
What is the main role of the cell-based prothrombinase complex?
Which of the following is a key function of thrombin in the coagulation process?
Which of the following is a key function of thrombin in the coagulation process?
What is the role of the Factor VIIIa/IXa complex in the coagulation cascade?
What is the role of the Factor VIIIa/IXa complex in the coagulation cascade?
What is the primary function of TFPI in the clotting process?
What is the primary function of TFPI in the clotting process?
Which of the following is a mechanism that limits the size of a clot in the coagulation process?
Which of the following is a mechanism that limits the size of a clot in the coagulation process?
How does the Fibrinolytic System regulate clot breakdown?
How does the Fibrinolytic System regulate clot breakdown?
What is the role of Factor XIII in the clotting cascade?
What is the role of Factor XIII in the clotting cascade?
Why are activated platelets considered essential for the clotting cascade?
Why are activated platelets considered essential for the clotting cascade?
What is the function of thrombin in the clotting cascade?
What is the function of thrombin in the clotting cascade?
In the classical clotting cascade, which pathway is activated when coagulation is initiated outside of the blood vessels?
In the classical clotting cascade, which pathway is activated when coagulation is initiated outside of the blood vessels?
What occurs at the endpoint of both intrinsic and extrinsic pathways in the clotting cascade?
What occurs at the endpoint of both intrinsic and extrinsic pathways in the clotting cascade?
Which enzyme is synthesized in the liver and is inactive until needed to digest fibrin?
Which enzyme is synthesized in the liver and is inactive until needed to digest fibrin?
What is the role of tPA inhibitor (tPAI) in the fibrinolysis process?
What is the role of tPA inhibitor (tPAI) in the fibrinolysis process?
Which test assesses the intrinsic and final common pathway of coagulation?
Which test assesses the intrinsic and final common pathway of coagulation?
What is the mechanism by which plasmin degrades fibrin?
What is the mechanism by which plasmin degrades fibrin?
Which factor must be reduced by more than 30% before a change in Prothrombin Time (PT) is observed?
Which factor must be reduced by more than 30% before a change in Prothrombin Time (PT) is observed?
What does Alpha-2 antiplasmin do in the context of fibrinolysis?
What does Alpha-2 antiplasmin do in the context of fibrinolysis?
INR stands for International Normalization Ratio.
INR stands for International Normalization Ratio.
The normal value of INR is around 3.
The normal value of INR is around 3.
Activated Clotting Time (ACT) is measured after heparin administration only.
Activated Clotting Time (ACT) is measured after heparin administration only.
Platelet Count measures the function of platelets.
Platelet Count measures the function of platelets.
ACT should be greater than 400 seconds before going on CPB.
ACT should be greater than 400 seconds before going on CPB.
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