Questions and Answers
What is the generic name of Cefaclor?
What is the trade name of Cefaclor?
Ceclor
What classification does Cefaclor belong to?
Antibiotic, Second - Generation Cephalosporin
What are the available forms of Cefaclor?
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What is the action of Cefaclor?
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What are the primary uses of Cefaclor?
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Cefaclor is contraindicated in patients with hypersensitivity to cephalosporins.
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What are some adverse effects of Cefaclor?
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What nursing implications should be considered before administering Cefaclor?
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Yogurt and milk can help maintain normal intestinal flora during Cefaclor therapy.
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Study Notes
Cefaclor Overview
- Generic Name: Cefaclor
- Trade Name: Ceclor
Classification and Formulation
- Classification: Antibiotic, Second-Generation Cephalosporin
- Availability: Offered in 250mg and 500mg capsules, 500mg sustained release tablets, and various suspension forms (e.g., 125mg/5ml, 250mg/5ml).
Mechanism of Action
- Action: Semisynthetic second-generation antibiotic effective against certain gram-negative bacteria, particularly beta-lactamase producing Haemophilus influenzae and resistant strains.
- Binding: Binds to penicillin-binding proteins on the cell walls of susceptible organisms.
Therapeutic Uses
- Indications: Treats otitis media, respiratory tract infections, urinary tract infections, and skin infections, particularly those caused by ampicillin-resistant strains.
Contraindications
- Hypersensitivity: Not recommended for patients with hypersensitivity to cephalosporins or related antibiotics.
Adverse Effects
- Common Reactions: May cause serum sickness-like reactions, eosinophilia, joint pain, fever, diarrhea, nausea, vomiting, and anorexia.
- Rare Complications: Pseudomembranous colitis; dermatological reactions include urticaria, pruritus, and morbilliform eruptions.
Nursing Implications
- Assessment: Check for any history of hypersensitivity to cephalosporins or other antibiotics before initiating treatment.
- Monitoring: Regular culture and sensitivity tests during therapy. Report persistent diarrhea and monitor allergic reactions or signs of superinfection.
Patient Education
- Awareness: Patients advised to report any signs of superinfection.
- Prophylactic Measures: Consuming yogurt and milk may help maintain intestinal flora and prevent superinfections, if appropriate.
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Description
Test your knowledge about Cefaclor with these flashcards! This quiz covers important details such as its generic and trade names, classification, availability, and action. Perfect for pharmacy students or anyone interested in antibiotic medications.