CDC Classification of Tuberculin Test

Which of the following is NOT a member of the Mycobacterium tuberculosis complex?

Mycobacterium africanum

Mycobacterium pinnipedii (correct)

Mycobacterium tuberculosis

Mycobacterium bovis

Which of the following is a characteristic of Mycobacterium tuberculosis?

Motile rod

Acid-fast (correct)

Spore-forming

Gram-negative

Which disease is caused by Mycobacterium tuberculosis?

Malaria

Meningitis

Influenza

Pneumonia (correct)

Which method is considered the gold standard for laboratory confirmation of tuberculosis?

Culture method Signup and view all the answers

What is the advantage of using molecular methods for detecting mycobacteria?

They provide rapid results Signup and view all the answers

Which method uses an oligonucleotide probe labeled with a detector molecule to identify M.tuberculosis?

In Situ Hybridization Signup and view all the answers

Which diagnostic test is endorsed by WHO for use in TB endemic countries?

Xpert MTB/RIF Signup and view all the answers

Which of the following is the primary mode of transmission for tuberculosis?

Inhalation of droplet nuclei Signup and view all the answers

What is the form of tuberculosis that develops in a previously unexposed person?

Primary tuberculosis Signup and view all the answers

Which of the following is the greatest known risk factor for progression of latent tuberculosis infection to active tuberculosis?

HIV infection Signup and view all the answers

Which diagnostic test is used to establish the presence of active tuberculosis?

Sputum smear Signup and view all the answers

Which test is used to measure the diameter of induration after 48-72 hours of injecting PPD on the volar surface of the forearm?

Mantoux test Signup and view all the answers

What is the interpretation of an induration size of 5-15 mm in the Mantoux test?

Positive for person with no known risk factor for TB Signup and view all the answers

Which test differentiates M. tuberculosis infection from previous BCG vaccination and most non-tuberculous mycobacteria?

Interferon gamma release assay (IGRA) Signup and view all the answers

What is the definition of Tuberculin test conversion?

An increase of > 10 mm within a 2 year period Signup and view all the answers

Which two drugs are commonly used in the treatment of drug-resistant TB?

Isoniazid and Rifampicin Signup and view all the answers

What is the definition of XDR-TB?

TB caused by M. tuberculosis strains that are resistant to isoniazid, rifampicin, any fluoroquinolone, and either bedaquiline or linezolid Signup and view all the answers

What is the preferred treatment regimen for drug-resistant TB?

INH, RIF, PZA, EMB daily or 5 days a week Signup and view all the answers

What were the drugs used in the Nix-TB trial?

Bedaquiline, Pretomanid, and Linezolid Signup and view all the answers