Causes of Cellular Damage Quiz

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Questions and Answers

Which disease is probably the most common cause of mouth ulcers?

  • Recurrent aphthous stomatitis (correct)
  • Infection
  • Trauma
  • Immunologically-mediated

What is the typical mechanism of trauma-related oral ulceration?

  • Viral infection
  • Autoimmune response
  • Physical impact (correct)
  • Chemical exposure

Which type of disease can oral ulceration be a feature of?

  • Iatrogenic disease
  • Vasculitic or granulomatous disease (correct)
  • Malignancy
  • Infectious disease

What is the most typically associated malignancy with oral ulceration?

<p>Oral squamous cell carcinoma (OSCC) (A)</p> Signup and view all the answers

Which lifestyle factor is mentioned as influencing oral disease?

<p>Smoking (A)</p> Signup and view all the answers

Which type of disease reflects anemia or neutropenia in relation to oral ulceration?

<p>Haematological/gastroenterological disease (B)</p> Signup and view all the answers

Which type of ulceration is typically short-term with well-defined features and is caused by viral infections?

<p>Infectious ulceration (C)</p> Signup and view all the answers

What are the reasons for changing patterns of infectious disease in relation to oral ulceration?

<p><strong>Improved public health measures and vaccinations</strong> (D)</p> Signup and view all the answers

What is the suggested association with H. pylori in relation to RAS?

<p>Indirect effect (C)</p> Signup and view all the answers

What is the observed allergy in some RAS patients that leads to lessening of ulceration following exclusion?

<p>Allergy to cow’s milk (D)</p> Signup and view all the answers

What is the mainstay of therapy for RAS according to the text?

<p>Topical corticosteroids (A)</p> Signup and view all the answers

What does the text suggest about the use of systemic corticosteroids for RAS?

<p>Not practical long term therapy (C)</p> Signup and view all the answers

What did the early studies observe about RAS in US students?

<p>RAS in 'stressed' US students (C)</p> Signup and view all the answers

What is the common feature of Behçet’s disease presentation according to the text?

<p>Recurrent oral and genital ulcers (A)</p> Signup and view all the answers

What does severe HIV disease occasionally cause in relation to RAS?

<p>Superficial ulceration (B)</p> Signup and view all the answers

What is the suggested association between inflammatory bowel disease and RAS?

<p>Superficial ulceration related to haematinic deficiency (D)</p> Signup and view all the answers

What is the initial suggestion regarding the use of Levamisole for RAS?

<p>'No benefit' (A)</p> Signup and view all the answers

What is the most common cause of mouth ulcers?

<p>Recurrent aphthous stomatitis (C)</p> Signup and view all the answers

What percentage of individuals is suggested to be affected by recurrent aphthous stomatitis?

<p>1.03% (C)</p> Signup and view all the answers

At what age does the frequency of recurrent aphthous stomatitis possibly decrease?

<p>After 40 years (B)</p> Signup and view all the answers

Which subtype of recurrent aphthous ulcer is extremely painful and interferes with speaking and eating?

<p>Herpetiform RAU (C)</p> Signup and view all the answers

What genetic predisposition is associated with recurrent aphthous stomatitis?

<p>Both parents having genetic predisposition (C)</p> Signup and view all the answers

Which of the following is NOT listed as an associated factor with recurrent aphthous stomatitis?

<p>Bacterial infections (B)</p> Signup and view all the answers

What type of T cells dominate in the pre-ulcerative stage of recurrent aphthous stomatitis?

<p>CD8+ T cells (D)</p> Signup and view all the answers

Which proinflammatory cytokines may be generated by antigenic stimulation of keratinocytes in recurrent aphthous stomatitis?

<p>$\text{IFN-γ}$ and $\text{TNF-α}$ (B)</p> Signup and view all the answers

What pattern of response may be at play in recurrent aphthous stomatitis, associated with a deranged TLR gene expression?

<p>Th1 response (B)</p> Signup and view all the answers

What is not associated with recurrent aphthous stomatitis?

<p>Antibody-mediated process (B)</p> Signup and view all the answers

What is the suggested pathergy test used for?

<p>Diagnosing Behcet's disease (D)</p> Signup and view all the answers

What is the major difference between RAU of Behcet's disease and common RAU?

<p>Greater involvement of soft palate and oropharynx (A)</p> Signup and view all the answers

What is the triad of symptoms associated with Reiter's Syndrome?

<p>Urethritis, arthritis, and conjunctivitis (D)</p> Signup and view all the answers

What is the main implication for dental professionals when suspecting Behcet's disease in a patient?

<p>Refer the patient to dermatologic &amp; ophthalmologic specialists (B)</p> Signup and view all the answers

What is the aim of the lecture on recurrent aphthous stomatitis (RAS) and related diseases?

<p>To detail the clinical, diagnostic and therapeutic aspects of RAS (B)</p> Signup and view all the answers

What does the Cochrane systematic review of 2012 conclude regarding the long-term benefit of local or systemic agents for RAS?

<p>No substantial evidence of long term benefit (C)</p> Signup and view all the answers

What are the adverse side effects of using systemic azathioprine for severe RAS disease?

<p>Well-known side effects with available monitoring guidelines (B)</p> Signup and view all the answers

'Mucocutaneous-occular syndromes' involve which parts of the body?

<p>Skin, oral mucosa, and eyes (C)</p> Signup and view all the answers

'Herptiform RAS' is typically treated with which of the following?

<p>Local anesthetic and tetracycline mouth bath (B)</p> Signup and view all the answers

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