Causes of Cellular Damage Quiz

Play an AI-generated podcast conversation about this lesson

Which disease is probably the most common cause of mouth ulcers?

Recurrent aphthous stomatitis (correct)

Infection

Trauma

Immunologically-mediated

What is the typical mechanism of trauma-related oral ulceration?

Viral infection

Autoimmune response

Physical impact (correct)

Chemical exposure

Which type of disease can oral ulceration be a feature of?

Iatrogenic disease

Vasculitic or granulomatous disease (correct)

Malignancy

Infectious disease

What is the most typically associated malignancy with oral ulceration?

Oral squamous cell carcinoma (OSCC) Signup and view all the answers

Which lifestyle factor is mentioned as influencing oral disease?

Smoking Signup and view all the answers

Which type of disease reflects anemia or neutropenia in relation to oral ulceration?

Haematological/gastroenterological disease Signup and view all the answers

Which type of ulceration is typically short-term with well-defined features and is caused by viral infections?

Infectious ulceration Signup and view all the answers

What are the reasons for changing patterns of infectious disease in relation to oral ulceration?

Improved public health measures and vaccinations Signup and view all the answers

What is the suggested association with H. pylori in relation to RAS?

Indirect effect Signup and view all the answers

What is the observed allergy in some RAS patients that leads to lessening of ulceration following exclusion?

Allergy to cow’s milk Signup and view all the answers

What is the mainstay of therapy for RAS according to the text?

Topical corticosteroids Signup and view all the answers

What does the text suggest about the use of systemic corticosteroids for RAS?

Not practical long term therapy Signup and view all the answers

What did the early studies observe about RAS in US students?

RAS in 'stressed' US students Signup and view all the answers

What is the common feature of Behçet’s disease presentation according to the text?

Recurrent oral and genital ulcers Signup and view all the answers

What does severe HIV disease occasionally cause in relation to RAS?

Superficial ulceration Signup and view all the answers

What is the suggested association between inflammatory bowel disease and RAS?

Superficial ulceration related to haematinic deficiency Signup and view all the answers

What is the initial suggestion regarding the use of Levamisole for RAS?

'No benefit' Signup and view all the answers

What is the most common cause of mouth ulcers?

Recurrent aphthous stomatitis Signup and view all the answers

What percentage of individuals is suggested to be affected by recurrent aphthous stomatitis?

1.03% Signup and view all the answers

At what age does the frequency of recurrent aphthous stomatitis possibly decrease?

After 40 years Signup and view all the answers

Which subtype of recurrent aphthous ulcer is extremely painful and interferes with speaking and eating?

Herpetiform RAU Signup and view all the answers

What genetic predisposition is associated with recurrent aphthous stomatitis?

Both parents having genetic predisposition Signup and view all the answers

Which of the following is NOT listed as an associated factor with recurrent aphthous stomatitis?

Bacterial infections Signup and view all the answers

What type of T cells dominate in the pre-ulcerative stage of recurrent aphthous stomatitis?

CD8+ T cells Signup and view all the answers

Which proinflammatory cytokines may be generated by antigenic stimulation of keratinocytes in recurrent aphthous stomatitis?

$\text{IFN-γ}$ and $\text{TNF-α}$ Signup and view all the answers

What pattern of response may be at play in recurrent aphthous stomatitis, associated with a deranged TLR gene expression?

Th1 response Signup and view all the answers

What is not associated with recurrent aphthous stomatitis?

Antibody-mediated process Signup and view all the answers

What is the suggested pathergy test used for?

Diagnosing Behcet's disease Signup and view all the answers

What is the major difference between RAU of Behcet's disease and common RAU?

Greater involvement of soft palate and oropharynx Signup and view all the answers

What is the triad of symptoms associated with Reiter's Syndrome?

Urethritis, arthritis, and conjunctivitis Signup and view all the answers

What is the main implication for dental professionals when suspecting Behcet's disease in a patient?

Refer the patient to dermatologic & ophthalmologic specialists Signup and view all the answers

What is the aim of the lecture on recurrent aphthous stomatitis (RAS) and related diseases?

To detail the clinical, diagnostic and therapeutic aspects of RAS Signup and view all the answers

What does the Cochrane systematic review of 2012 conclude regarding the long-term benefit of local or systemic agents for RAS?

No substantial evidence of long term benefit Signup and view all the answers

What are the adverse side effects of using systemic azathioprine for severe RAS disease?

Well-known side effects with available monitoring guidelines Signup and view all the answers

'Mucocutaneous-occular syndromes' involve which parts of the body?

Skin, oral mucosa, and eyes Signup and view all the answers

'Herptiform RAS' is typically treated with which of the following?

Local anesthetic and tetracycline mouth bath Signup and view all the answers