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What is a cataract and how does it affect vision?
What is a cataract and how does it affect vision?
A cataract is a light-scattering opacity within the lens that can lead to visual loss when it obstructs the visual axis.
Identify two environmental factors that may contribute to the development of age-related cataracts.
Identify two environmental factors that may contribute to the development of age-related cataracts.
Cumulative exposure to UV radiation and smoking are two environmental factors contributing to age-related cataracts.
Explain the impact of ocular trauma on cataract formation.
Explain the impact of ocular trauma on cataract formation.
Ocular trauma, including blunt and penetrating injuries, can lead to the development of cataracts by causing direct damage to the lens.
What role do systemic diseases play in cataract development?
What role do systemic diseases play in cataract development?
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How does uveitis potentially lead to cataract formation?
How does uveitis potentially lead to cataract formation?
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What effect does near vision have on pupil size and how does this relate to cataract vision obstruction?
What effect does near vision have on pupil size and how does this relate to cataract vision obstruction?
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Differentiate between immature and mature cataracts.
Differentiate between immature and mature cataracts.
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What characterizes a hypermature cataract?
What characterizes a hypermature cataract?
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What symptoms are commonly associated with cataracts?
What symptoms are commonly associated with cataracts?
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Explain the significance of signs found during an eye examination for cataracts.
Explain the significance of signs found during an eye examination for cataracts.
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What is one primary indication for cataract surgery?
What is one primary indication for cataract surgery?
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Describe the visual impact of a nuclear cataract.
Describe the visual impact of a nuclear cataract.
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What is a Morgagnian cataract, and how does it differ from a hypermature cataract?
What is a Morgagnian cataract, and how does it differ from a hypermature cataract?
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What constitutes a medical indication for cataract surgery?
What constitutes a medical indication for cataract surgery?
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Why is fundus examination significant in the context of cataract surgery?
Why is fundus examination significant in the context of cataract surgery?
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What does a cover test in ophthalmic preoperative assessment reveal?
What does a cover test in ophthalmic preoperative assessment reveal?
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What preoperative conditions of the ocular adnexa may necessitate resolution before cataract surgery?
What preoperative conditions of the ocular adnexa may necessitate resolution before cataract surgery?
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How does corneal health impact cataract surgery outcomes?
How does corneal health impact cataract surgery outcomes?
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What challenges can arise from a shallow anterior chamber before cataract surgery?
What challenges can arise from a shallow anterior chamber before cataract surgery?
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How do different types of cataracts affect the phacoemulsification process?
How do different types of cataracts affect the phacoemulsification process?
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In assessing current refractive status, what is the primary purpose before cataract surgery?
In assessing current refractive status, what is the primary purpose before cataract surgery?
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What is a Vossius ring and what does it indicate?
What is a Vossius ring and what does it indicate?
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Name two systemic drugs that can lead to posterior subcapsular cataracts.
Name two systemic drugs that can lead to posterior subcapsular cataracts.
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How does chronic anterior uveitis contribute to cataract formation?
How does chronic anterior uveitis contribute to cataract formation?
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What systemic cause of cataract is associated with congenital rubella?
What systemic cause of cataract is associated with congenital rubella?
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Describe the characteristic change seen in nuclear cataracts.
Describe the characteristic change seen in nuclear cataracts.
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What are glaukomflecken and in what context do they occur?
What are glaukomflecken and in what context do they occur?
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Identify one syndrome associated with cataract formation.
Identify one syndrome associated with cataract formation.
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How do metabolic disorders contribute to cataract formation?
How do metabolic disorders contribute to cataract formation?
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What are the potential consequences of congenital cataract on a child's vision?
What are the potential consequences of congenital cataract on a child's vision?
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Why is urgent surgery recommended for congenital cataract within the first few weeks of life?
Why is urgent surgery recommended for congenital cataract within the first few weeks of life?
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What role do contact lenses play in the treatment of aphakia in infants?
What role do contact lenses play in the treatment of aphakia in infants?
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How might cataract surgery in infants before one year of age pose a risk for glaucoma?
How might cataract surgery in infants before one year of age pose a risk for glaucoma?
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What is the difference between subluxation and dislocation of the lens in ectopia lentis?
What is the difference between subluxation and dislocation of the lens in ectopia lentis?
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What are some inherited disorders associated with ectopia lentis?
What are some inherited disorders associated with ectopia lentis?
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Why do problems with lens shape and position contribute to myopia?
Why do problems with lens shape and position contribute to myopia?
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What treatment methods are increasingly used for children over 2 years old with congenital cataracts?
What treatment methods are increasingly used for children over 2 years old with congenital cataracts?
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What is the significance of keratometry readings in refractive surgery planning?
What is the significance of keratometry readings in refractive surgery planning?
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How does biometry assist in determining the power of intraocular lenses (IOL)?
How does biometry assist in determining the power of intraocular lenses (IOL)?
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What is a common formula used for IOL power calculation, specifically for eyes with axial lengths greater than 22.0 mm?
What is a common formula used for IOL power calculation, specifically for eyes with axial lengths greater than 22.0 mm?
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Why is it necessary for patients to refrain from wearing contact lenses before undergoing biometry?
Why is it necessary for patients to refrain from wearing contact lenses before undergoing biometry?
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What technology is commonly used for non-contact axial measurements in biometry?
What technology is commonly used for non-contact axial measurements in biometry?
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What factors influence the choice of IOL power during cataract surgery planning?
What factors influence the choice of IOL power during cataract surgery planning?
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Explain the role of the Zeiss IOLMaster in preoperative assessments.
Explain the role of the Zeiss IOLMaster in preoperative assessments.
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What is the importance of analyzing postoperative refractive results in previously operated eyes?
What is the importance of analyzing postoperative refractive results in previously operated eyes?
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What is the initial appearance of nuclear sclerosis and how does it relate to presbyopia?
What is the initial appearance of nuclear sclerosis and how does it relate to presbyopia?
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Describe the progression of cortical cataracts and the visual symptoms they typically cause.
Describe the progression of cortical cataracts and the visual symptoms they typically cause.
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How do posterior subcapsular cataracts differ from nuclear and cortical cataracts in terms of vision impairment?
How do posterior subcapsular cataracts differ from nuclear and cortical cataracts in terms of vision impairment?
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What morphological changes occur in the lens during the development of nuclear cataracts?
What morphological changes occur in the lens during the development of nuclear cataracts?
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What specific changes are involved in the formation of anterior subcapsular cataracts?
What specific changes are involved in the formation of anterior subcapsular cataracts?
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How does spherical aberration affect vision in relation to lens function?
How does spherical aberration affect vision in relation to lens function?
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In cataract progression, what is the significance of the 'clefts and vacuoles' observed in cortical cataracts?
In cataract progression, what is the significance of the 'clefts and vacuoles' observed in cortical cataracts?
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Explain the relationship between aging, nuclear sclerosis, and the concept of 'second sight.'
Explain the relationship between aging, nuclear sclerosis, and the concept of 'second sight.'
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What causes the formation of a Vossius ring in the context of ocular trauma?
What causes the formation of a Vossius ring in the context of ocular trauma?
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Which drugs are commonly associated with posterior subcapsular cataract formation?
Which drugs are commonly associated with posterior subcapsular cataract formation?
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Explain the term 'glaukomflecken' and its clinical significance.
Explain the term 'glaukomflecken' and its clinical significance.
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What is the relationship between nuclear cataract and myopia?
What is the relationship between nuclear cataract and myopia?
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Identify a syndrome associated with congenital cataract and explain its significance.
Identify a syndrome associated with congenital cataract and explain its significance.
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Discuss how metabolic disorders contribute to cataract formation.
Discuss how metabolic disorders contribute to cataract formation.
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What is the main surgical approach for cataract removal and how is it usually performed?
What is the main surgical approach for cataract removal and how is it usually performed?
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How does chronic anterior uveitis increase the risk of cataract formation?
How does chronic anterior uveitis increase the risk of cataract formation?
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What is the impact of ionizing radiation on cataract formation?
What is the impact of ionizing radiation on cataract formation?
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Prior to cataract surgery, what important information must be conveyed to patients regarding coexisting conditions?
Prior to cataract surgery, what important information must be conveyed to patients regarding coexisting conditions?
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What potential visual symptoms indicate the need for cataract surgery?
What potential visual symptoms indicate the need for cataract surgery?
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What is the significance of using a toric intraocular lens in cataract surgery?
What is the significance of using a toric intraocular lens in cataract surgery?
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Describe the role of local anesthesia in cataract surgery.
Describe the role of local anesthesia in cataract surgery.
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What innovations are currently being explored in cataract surgery techniques?
What innovations are currently being explored in cataract surgery techniques?
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Why is it important for younger patients to understand the adjustment time after cataract surgery?
Why is it important for younger patients to understand the adjustment time after cataract surgery?
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What is the role of the plastic lens implant after cataract surgery?
What is the role of the plastic lens implant after cataract surgery?
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What can trigger the onset of squint in infants with bilateral cataracts?
What can trigger the onset of squint in infants with bilateral cataracts?
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How does the timing of cataract surgery impact the risk of subsequent glaucoma in infants?
How does the timing of cataract surgery impact the risk of subsequent glaucoma in infants?
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Why is a coordinated patching routine essential for children with congenital cataracts?
Why is a coordinated patching routine essential for children with congenital cataracts?
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Discuss the relationship between ectopia lentis and myopia.
Discuss the relationship between ectopia lentis and myopia.
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What complications may arise from the surgery of congenital cataracts in infants?
What complications may arise from the surgery of congenital cataracts in infants?
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How does homocystinuria relate to lens position abnormalities?
How does homocystinuria relate to lens position abnormalities?
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In the context of congenital cataracts, why is fitting contact lenses a significant challenge for parents?
In the context of congenital cataracts, why is fitting contact lenses a significant challenge for parents?
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What are the characteristics of anterior lenticonus associated with Alport's syndrome?
What are the characteristics of anterior lenticonus associated with Alport's syndrome?
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Study Notes
Cataract
- A light-scattering opacity within the lens
- Can lead to visual loss when it impedes visual axis
- Most common cause of blindness in the world
- Majority of cataracts are age related, developing as a consequence of UV exposure, poor diet, chronic disease, smoking etc.
- Can be caused by specific ocular or systemic disease, some are inherited
Causes of Cataract
-
Ocular Trauma
- Penetrating injury
- Blunt trauma to the globe
- Ionizing radiation
- Infrared radiation
- Electrical shock
-
Uveitis
- Unilateral if affecting only one eye
- High Myopia
-
Topical Medications
- Steroid eye drops
-
Intraocular Tumor
- Ciliary body tumors can physically affect the lens
-
Acute Angle-Closure Glaucoma
- Glaukomflecken on anterior capsule
-
Concussion
- Vossius' ring from imprinting of iris pigment
-
Penetrating
- Flower-shaped
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Other Causes
- Ionizing radiation
- Electric shock
- Lightning
-
Drugs
- Systemic or Topical steroids
- Posterior subcapsular
- Chlorpromazine
- Central, anterior capsular granules
- Other drugs:
- Long-acting miotics
- Amiodarone
- Busulphan
-
Secondary (Complicated) cataract
- Posterior subcapsular
- Glaukomflecken
- Chronic anterior uveitis
- Follows acute angle-closure glaucoma
-
Systemic Causes
- Diabetes
- Metabolic disorders (galactosemia and hypocalcemia)
- Systemic drugs (steroids, chlorpromazine, Amiodarone)
- X-radiation
- Infection (congenital rubella)
- Atopy (accompanying atopic dermatitis)
- Inherited (congenital cataracts and some adult cataracts as in myotonic dystrophy, Neurofibromatosis 2)
- Syndromes (Down syndrome, Lowe syndrome)
Classification According to Location
-
Nuclear Cataract
- Starts as an exaggeration of the normal aging changes involving the lens nucleus
- Often associated with myopia due to the increased refractive index of the nucleus, and also with increased spherical aberration
- May cause patients to be able to read without spectacles again ('second sight of the aged')
-
Subcapsular Cataract
- Anterior
- Posterior
Classification According to Maturity
-
Immature Cataract
- Lens is partially opaque
-
Mature Cataract
- Lens is completely opaque
-
Hypermature Cataract
- Anterior capsule is shrunken and wrinkled due to water leakage from the lens
-
Morgagnian Cataract
- Hypermature cataract in which the nucleus has sunk inferiorly due to liquefaction of the cortex
Signs and Symptoms
-
Symptoms
- Painless loss of vision
- Glare due to light scattering
- Change in refraction (myopic shift with nuclear cataract)
- In neonates and infants, cataract causes amblyopia (failure of visual maturation)
-
Signs
- Reduced visual acuity
- Impaired reading at all distances
- Reduced ability for night driving due to glare
- Reduced acuity in bright light
- Cataract appears as a dark silhouette against the red reflex.
Preoperative Considerations
-
Indications for Surgery
- Visual improvement: most common indication
- Medical indications: phacolytic or phacomorphic glaucoma
- To Facilitate Fundus Examination: required in the context of fundal pathology requiring monitoring or treatment.
-
Ophthalmic Preoperative Assessment
- Visual Acuity: tested using a Snellen chart
- Cover Test: can indicate amblyopia or diplopia if vision is improved.
- Pupillary Responses: presence of pupillary defect suggests additional pathology
- Ocular Adnexa: Dacryocystitis, blepharitis, chronic conjunctivitis, lagophthalmos, ectropion, entropion and tear film abnormalities can predispose to endophthalmitis
- Cornea: Eyes with decreased endothelial cell counts are vulnerable to postoperative decompensation.
- Anterior Chamber: shallow chamber, poorly dilating pupil may require preoperative mydriatic drops.
- Lens: Nuclear cataracts tend to be harder for phacoemulsification, while cortical opacities tend to be softer. Black nuclear opacities are extremely dense.
- Fundus Examination: Pathology such as age-related macular degeneration may affect visual outcome.
- Current Refractive Status: Guides intraocular lens implant (IOL) selection.
Congenital and Infantile Cataracts
- Threat to sight: immediate obstruction and disturbance to retinal image formation
- Can lead to amblyopia, squint or nystagmus
- Requires urgent surgery within the first few weeks of life
Disorders of Lens Shape
- Abnormal lens shape is very unusual
- Alport’s syndrome (anterior lenticonus) - bilateral, conical protrusion of the anterior lens surface
- Posterior lenticonus (non-syndromic, unilateral condition)
- Abnormal small lens can be associated with short stature and other skeletal abnormalities.
Disorders of Lens Position (Ectopia lentis)
- Subluxation - minor displacement of the lens caused by weakness of the zonule
- Dislocation - more significant displacement
- Homocystinuria - recessive disorder with ectopia lentis (displaced downwards)
- Marfan Syndrome - displaced lens upwards, defect in the zonular protein (mutation in the fibrillin gene).
- Ocular trauma can also cause lens displacement
### Traumatic Cataract
-
Caused by blunt trauma, penetrating trauma, ionizing radiation, electric shock, and lightning.
-
Blunt trauma can result in a Vossius ring, flower-shaped imprinting of iris pigment onto anterior lens capsule.
Drug-Induced Cataract
-
Systemic and topical steroids, chlorpromazine, and long-acting miotics can all cause cataracts.
-
Chlorpromazine can cause central anterior capsular granules.
Secondary (Complicated) Cataract
- Posterior subcapsular cataracts commonly follow chronic anterior uveitis and acute angle-closure glaucoma.
Systemic Causes of Cataract
-
Diabetes, metabolic disorders (galactosemia and hypocalcemia), systemic drugs (steroids, chlorpromazine, Amiodarone), X-radiation, congenital rubella, atopy, and inherited conditions are common systemic causes.
-
Specific inherited conditions include myotonic dystrophy, Neurofibromatosis 2, Down syndrome, and Lowe syndrome.
Nuclear Cataract
-
Starts as an exaggeration of normal aging changes involving the lens nucleus.
-
Often associated with myopia due to increased refractive index of the nucleus.
-
Can lead to "second sight of the aged" where patients can read without glasses again.
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Early stages characterized by a yellowish hue due to urochrome pigment deposition.
-
Spherical aberration can occur due to the outer parts of the lens not focusing light rays at the same point as the central part.
Cortical Cataract
-
May affect the anterior, posterior, or equatorial cortex.
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Initially appears as clefts and vacuoles between lens fibers due to hydration of the cortex.
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Forms typical cuneiform (wedge-shaped) or radial spoke-like opacities, often in the inferonasal quadrant.
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Patients often experience glare due to light scattering.
Subcapsular Cataract
-
Anterior subcapsular cataracts are located directly under the lens capsule and are associated with fibrous metaplasia of the lens epithelium.
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Posterior subcapsular opacities lie just in front of the posterior capsule and have a vacuolated, granular, or plaque-like appearance, appearing black on retroillumination.
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Often caused by diabetes, steroid use, and uveitis.
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Because of its location at the nodal point of the eye, a posterior subcapsular opacity has a more significant impact on vision than a comparable nuclear or cortical cataract.
-
Near vision is often impaired more than distance vision.
Cataract Surgery
-
Requires access to the lens through an opening in the anterior lens capsule.
-
Involves removing most lens fibers and epithelial cells.
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Inserts a plastic lens implant of appropriate optical power.
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Implant (IOL) is held in place within the capsular bag.
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Usually performed under local anesthesia.
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Phacoemulsification (phaco) is the preferred method of lens removal, using an ultrasound probe introduced through a small incision at the limbus.
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Femtosecond lasers are increasingly used to make incisions in the cornea, anterior capsule, and partially emulsify the lens.
Congenital Cataract
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A threat to sight due to the immediate obstruction of vision and disturbance to retinal image formation during visual development.
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Leads to impaired visual maturation and amblyopia.
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Triggers the onset of squint.
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Bilateral cataract can cause bilateral amblyopia, squint, and nystagmus.
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Risk of subsequent glaucoma is significant, particularly in infants undergoing surgery before 1 year of age.
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Urgent surgery is required within the first few weeks of life to maximize the chances of success.
Disorders of Lens Shape
-
Abnormal lens shape is unusual.
-
Anterior lenticonus (bilateral, conical anterior protrusion) can occur in Alport’s syndrome.
-
Posterior lenticonus (non-syndromic, unilateral condition) can also occur.
-
An abnormally small lens may be associated with short stature and other skeletal abnormalities.
Disorders of Lens Position (Ectopia Lentis)
-
Weakness of the zonule causes lens displacement, termed subluxation if minor, or dislocation when more advanced.
-
The lens takes on a more rounded form, and the eye becomes more myopic.
-
Caused by ocular trauma, homocystinuria (recessive disorder with lens displaced downwards), Marfan syndrome (lens displaced upwards), and defects in the zonular protein (mutation in the fibrillin gene).
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Description
This quiz covers the essential information about cataracts, including their characteristics and various causes. Learn about how cataracts can lead to visual impairment and the risk factors associated with their development. Test your knowledge on ocular trauma, uveitis, and other contributing factors to cataract formation.