Carvedilol Flashcards - Beta Blockers
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Questions and Answers

What is the trade name of carvedilol?

  • Coreg
  • Coreg CR
  • Both Coreg and Coreg CR (correct)
  • None of the above

What is the therapeutic effect of carvedilol?

Decreased heart rate and BP. Improved cardiac output, slowing of the progression of HF and decreased risk of death.

What are the side effects of carvedilol?

CNS: dizziness, fatigue, weakness. CV: bradycardia, HF, pulmonary edema. GI: diarrhea. GU: erectile dysfunction. Derm: Stevens-Johnson syndrome, toxic epidermal necrolysis. Endo: hyperglycemia. Misc: anaphylaxis, angioedema.

What is the interaction of carvedilol?

<p>Increased risk of bradycardia with digoxin; clonidine increases hypotension and bradycardia; may decrease beneficial beta1-cardiovascular effects of dopamine or dobutamine; cimetidine may increase toxicity from carvedilol; NSAIDs may decrease antihypertensive action; may increase blood levels of cyclosporine.</p> Signup and view all the answers

To whom is carvedilol contraindicated?

<p>Hypersensitivity reactions, pulmonary edema, cardiogenic shock, bradycardia, heart block or sick sinus syndrome, uncompensated HF requiring IV inotropic agents, severe hepatic impairment, asthma or other bronchospastic disorders.</p> Signup and view all the answers

What is involved in nurse assessment for a patient on carvedilol?

<p>Monitor BP and pulse frequently, assess for orthostatic hypotension, monitor intake and output ratios, assess for fluid overload symptoms, and observe lab test considerations.</p> Signup and view all the answers

What should be included in patient teaching regarding carvedilol?

<p>Abrupt withdrawal may precipitate life-threatening arrhythmias, hypertension, or myocardial ischemia; notify healthcare professional if slow pulse, difficulty breathing, wheezing, cold extremities, dizziness, or unusual symptoms occur.</p> Signup and view all the answers

Study Notes

Carvedilol Overview

  • Trade names: Coreg, Coreg CR
  • Class: Anti-adrenergic beta blocker

Therapeutic Effects

  • Reduces heart rate and blood pressure
  • Enhances cardiac output
  • Slows progression of heart failure (HF)
  • Decreases risk of mortality

Side Effects

  • CNS: Dizziness, fatigue, weakness
  • Cardiovascular: Bradycardia, heart failure, pulmonary edema
  • Gastrointestinal: Diarrhea
  • Genitourinary: Erectile dysfunction
  • Dermatological: Stevens-Johnson syndrome, toxic epidermal necrolysis
  • Endocrine: Hyperglycemia
  • Miscellaneous: Anaphylaxis, angioedema

Drug Interactions

  • Increased risk of bradycardia with digoxin
  • Clonidine may exacerbate hypotension and bradycardia
  • Can reduce the cardiovascular effects of dopamine or dobutamine
  • Cimetidine may heighten carvedilol toxicity
  • NSAIDs potentially diminish antihypertensive efficacy
  • May elevate blood levels of cyclosporine

Contraindications

  • Hypersensitivity reactions (e.g., Stevens-Johnson syndrome, angioedema, anaphylaxis)
  • Conditions such as pulmonary edema and cardiogenic shock
  • Bradycardia, heart block, or sick sinus syndrome (unless a pacemaker is present)
  • Uncompensated heart failure requiring IV inotropic therapy
  • Severe hepatic impairment
  • Asthma or other bronchospastic disorders

Nurse Assessment Guidelines

  • Monitor blood pressure and pulse closely during dose adjustments and therapy
  • Assess for orthostatic hypotension when changing patient position
  • Track intake/output ratios and daily weight
  • Monitor for signs of fluid overload (edema, dyspnea, fatigue, weight gain)
  • Be aware of potential symptom worsening during HF treatment initiation
  • Lab tests: May rise BUN, serum lipoprotein, potassium, triglycerides, uric acid; may increase ANA titers and blood glucose levels

Patient Teaching

  • Warn against abrupt cessation, which can lead to severe arrhythmias, hypertension, or myocardial ischemia
  • Instruct patients to report symptoms such as slow pulse, respiratory issues, dizziness, confusion, depression, skin rashes, fever, sore throat, or unusual bleeding/bruising immediately.

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Test your knowledge on carvedilol, an anti-adrenergic beta blocker, with these flashcards. Explore trade names, therapeutic effects, and side effects to enhance your understanding of this medication. Perfect for students and healthcare professionals alike!

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