Questions and Answers
What is the trade name of carvedilol?
What is the therapeutic effect of carvedilol?
Decreased heart rate and BP. Improved cardiac output, slowing of the progression of HF and decreased risk of death.
What are the side effects of carvedilol?
CNS: dizziness, fatigue, weakness. CV: bradycardia, HF, pulmonary edema. GI: diarrhea. GU: erectile dysfunction. Derm: Stevens-Johnson syndrome, toxic epidermal necrolysis. Endo: hyperglycemia. Misc: anaphylaxis, angioedema.
What is the interaction of carvedilol?
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To whom is carvedilol contraindicated?
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What is involved in nurse assessment for a patient on carvedilol?
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What should be included in patient teaching regarding carvedilol?
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Study Notes
Carvedilol Overview
- Trade names: Coreg, Coreg CR
- Class: Anti-adrenergic beta blocker
Therapeutic Effects
- Reduces heart rate and blood pressure
- Enhances cardiac output
- Slows progression of heart failure (HF)
- Decreases risk of mortality
Side Effects
- CNS: Dizziness, fatigue, weakness
- Cardiovascular: Bradycardia, heart failure, pulmonary edema
- Gastrointestinal: Diarrhea
- Genitourinary: Erectile dysfunction
- Dermatological: Stevens-Johnson syndrome, toxic epidermal necrolysis
- Endocrine: Hyperglycemia
- Miscellaneous: Anaphylaxis, angioedema
Drug Interactions
- Increased risk of bradycardia with digoxin
- Clonidine may exacerbate hypotension and bradycardia
- Can reduce the cardiovascular effects of dopamine or dobutamine
- Cimetidine may heighten carvedilol toxicity
- NSAIDs potentially diminish antihypertensive efficacy
- May elevate blood levels of cyclosporine
Contraindications
- Hypersensitivity reactions (e.g., Stevens-Johnson syndrome, angioedema, anaphylaxis)
- Conditions such as pulmonary edema and cardiogenic shock
- Bradycardia, heart block, or sick sinus syndrome (unless a pacemaker is present)
- Uncompensated heart failure requiring IV inotropic therapy
- Severe hepatic impairment
- Asthma or other bronchospastic disorders
Nurse Assessment Guidelines
- Monitor blood pressure and pulse closely during dose adjustments and therapy
- Assess for orthostatic hypotension when changing patient position
- Track intake/output ratios and daily weight
- Monitor for signs of fluid overload (edema, dyspnea, fatigue, weight gain)
- Be aware of potential symptom worsening during HF treatment initiation
- Lab tests: May rise BUN, serum lipoprotein, potassium, triglycerides, uric acid; may increase ANA titers and blood glucose levels
Patient Teaching
- Warn against abrupt cessation, which can lead to severe arrhythmias, hypertension, or myocardial ischemia
- Instruct patients to report symptoms such as slow pulse, respiratory issues, dizziness, confusion, depression, skin rashes, fever, sore throat, or unusual bleeding/bruising immediately.
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Description
Test your knowledge on carvedilol, an anti-adrenergic beta blocker, with these flashcards. Explore trade names, therapeutic effects, and side effects to enhance your understanding of this medication. Perfect for students and healthcare professionals alike!
