Cartilage Tensile Modulus Quiz
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Questions and Answers

Which of the following is NOT a factor that affects the tensile modulus (stiffness) of cartilage?

  • Density of collagen fibers
  • Type or amount of collagen cross linking
  • Orientation of collagen fibers
  • Articular cartilage's permeability under compression (correct)
  • As the density of collagen fibers in cartilage increases, the tensile modulus (stiffness) of the tissue will typically:

  • Decrease
  • Remain constant
  • Increase (correct)
  • Become more variable
  • How does the orientation of collagen fibers in cartilage affect the tensile modulus (stiffness) of the tissue?

  • Tensile modulus is independent of collagen fiber orientation
  • Tensile modulus varies inversely with the degree of fiber alignment
  • Fibers oriented perpendicular to the joint surface have higher tensile modulus
  • Fibers oriented parallel to the joint surface have higher tensile modulus (correct)
  • How does the degree of collagen cross-linking in cartilage affect its tensile modulus (stiffness)?

    <p>Increased cross-linking increases tensile modulus</p> Signup and view all the answers

    How does the permeability of articular cartilage change with increasing compressive strain and pressure?

    <p>Permeability decreases exponentially</p> Signup and view all the answers

    Which of the following factors can cause variations in the tensile modulus (stiffness) of articular cartilage?

    <p>All of the above</p> Signup and view all the answers

    What is the primary factor that governs the normal swelling behavior of articular cartilage?

    <p>Maintenance of the collagen-proteoglycan network integrity</p> Signup and view all the answers

    What is the primary cause of the viscoelastic behavior of articular cartilage?

    <p>All of the above</p> Signup and view all the answers

    What is the relationship between the hydraulic permeability 'k' and the creep behavior of cartilage in a confined compression test?

    <p>Creep is controlled by the exudation of fluid through the porous platen, and the movement of fluid is controlled by the hydraulic permeability 'k'</p> Signup and view all the answers

    How does the collagen-proteoglycan network integrity affect the hydration of articular cartilage?

    <p>Healthy cartilage with intact collagen-proteoglycan network shows less than 3% weight change, while degenerate cartilage shows significantly greater (~30%) weight change</p> Signup and view all the answers

    How does the orientation of the collagen fibers in articular cartilage affect its mechanical properties?

    <p>The text does not provide any information about the relationship between collagen fiber orientation and the mechanical properties of articular cartilage</p> Signup and view all the answers

    How does the degree of cross-linking in the collagen fibers affect the tensile modulus of articular cartilage?

    <p>The text does not provide any information about the relationship between collagen cross-linking and the tensile modulus of articular cartilage</p> Signup and view all the answers

    Which region of the tensile force-deformation curve for cartilage corresponds to the straightening and un-crimping of collagen fibrils?

    <p>The toe region</p> Signup and view all the answers

    In the linear region of the tensile force-deformation curve for cartilage, what is the behavior of the collagen fibrils?

    <p>The collagen fibrils are aligned parallel to the axis of tension</p> Signup and view all the answers

    Which of the following factors contributes to the anisotropic mechanical behavior of cartilage?

    <p>Inhomogeneous distribution of collagen fibrils and proteoglycans</p> Signup and view all the answers

    Under compressive loading, which of the following mechanisms contributes to the resistance of cartilage to compression?

    <p>The osmotic swelling pressure increases, and the resistance to compression is achieved</p> Signup and view all the answers

    Which of the following statements is true regarding the tensile modulus of cartilage?

    <p>The tensile modulus is higher in regions with higher collagen fibril density</p> Signup and view all the answers

    Which of the following factors contributes to the high compressive stiffness of cartilage?

    <p>The presence of a high concentration of fixed negative charges on the proteoglycans</p> Signup and view all the answers

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