18 Questions
Which of the following is NOT a factor that affects the tensile modulus (stiffness) of cartilage?
Articular cartilage's permeability under compression
As the density of collagen fibers in cartilage increases, the tensile modulus (stiffness) of the tissue will typically:
Increase
How does the orientation of collagen fibers in cartilage affect the tensile modulus (stiffness) of the tissue?
Fibers oriented parallel to the joint surface have higher tensile modulus
How does the degree of collagen cross-linking in cartilage affect its tensile modulus (stiffness)?
Increased cross-linking increases tensile modulus
How does the permeability of articular cartilage change with increasing compressive strain and pressure?
Permeability decreases exponentially
Which of the following factors can cause variations in the tensile modulus (stiffness) of articular cartilage?
All of the above
What is the primary factor that governs the normal swelling behavior of articular cartilage?
Maintenance of the collagen-proteoglycan network integrity
What is the primary cause of the viscoelastic behavior of articular cartilage?
All of the above
What is the relationship between the hydraulic permeability 'k' and the creep behavior of cartilage in a confined compression test?
Creep is controlled by the exudation of fluid through the porous platen, and the movement of fluid is controlled by the hydraulic permeability 'k'
How does the collagen-proteoglycan network integrity affect the hydration of articular cartilage?
Healthy cartilage with intact collagen-proteoglycan network shows less than 3% weight change, while degenerate cartilage shows significantly greater (~30%) weight change
How does the orientation of the collagen fibers in articular cartilage affect its mechanical properties?
The text does not provide any information about the relationship between collagen fiber orientation and the mechanical properties of articular cartilage
How does the degree of cross-linking in the collagen fibers affect the tensile modulus of articular cartilage?
The text does not provide any information about the relationship between collagen cross-linking and the tensile modulus of articular cartilage
Which region of the tensile force-deformation curve for cartilage corresponds to the straightening and un-crimping of collagen fibrils?
The toe region
In the linear region of the tensile force-deformation curve for cartilage, what is the behavior of the collagen fibrils?
The collagen fibrils are aligned parallel to the axis of tension
Which of the following factors contributes to the anisotropic mechanical behavior of cartilage?
Inhomogeneous distribution of collagen fibrils and proteoglycans
Under compressive loading, which of the following mechanisms contributes to the resistance of cartilage to compression?
The osmotic swelling pressure increases, and the resistance to compression is achieved
Which of the following statements is true regarding the tensile modulus of cartilage?
The tensile modulus is higher in regions with higher collagen fibril density
Which of the following factors contributes to the high compressive stiffness of cartilage?
The presence of a high concentration of fixed negative charges on the proteoglycans
Test your knowledge on the factors affecting tensile modulus of cartilage, such as collagen fibers density, orientation, and cross-linking. Understand how tensile modulus varies based on joint surface location and specimen depth.
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