Cartilage Tensile Modulus Quiz
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Questions and Answers

Which of the following is NOT a factor that affects the tensile modulus (stiffness) of cartilage?

  • Density of collagen fibers
  • Type or amount of collagen cross linking
  • Orientation of collagen fibers
  • Articular cartilage's permeability under compression (correct)

As the density of collagen fibers in cartilage increases, the tensile modulus (stiffness) of the tissue will typically:

  • Decrease
  • Remain constant
  • Increase (correct)
  • Become more variable

How does the orientation of collagen fibers in cartilage affect the tensile modulus (stiffness) of the tissue?

  • Tensile modulus is independent of collagen fiber orientation
  • Tensile modulus varies inversely with the degree of fiber alignment
  • Fibers oriented perpendicular to the joint surface have higher tensile modulus
  • Fibers oriented parallel to the joint surface have higher tensile modulus (correct)

How does the degree of collagen cross-linking in cartilage affect its tensile modulus (stiffness)?

<p>Increased cross-linking increases tensile modulus (A)</p> Signup and view all the answers

How does the permeability of articular cartilage change with increasing compressive strain and pressure?

<p>Permeability decreases exponentially (C)</p> Signup and view all the answers

Which of the following factors can cause variations in the tensile modulus (stiffness) of articular cartilage?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary factor that governs the normal swelling behavior of articular cartilage?

<p>Maintenance of the collagen-proteoglycan network integrity (D)</p> Signup and view all the answers

What is the primary cause of the viscoelastic behavior of articular cartilage?

<p>All of the above (D)</p> Signup and view all the answers

What is the relationship between the hydraulic permeability 'k' and the creep behavior of cartilage in a confined compression test?

<p>Creep is controlled by the exudation of fluid through the porous platen, and the movement of fluid is controlled by the hydraulic permeability 'k' (A)</p> Signup and view all the answers

How does the collagen-proteoglycan network integrity affect the hydration of articular cartilage?

<p>Healthy cartilage with intact collagen-proteoglycan network shows less than 3% weight change, while degenerate cartilage shows significantly greater (~30%) weight change (A)</p> Signup and view all the answers

How does the orientation of the collagen fibers in articular cartilage affect its mechanical properties?

<p>The text does not provide any information about the relationship between collagen fiber orientation and the mechanical properties of articular cartilage (A)</p> Signup and view all the answers

How does the degree of cross-linking in the collagen fibers affect the tensile modulus of articular cartilage?

<p>The text does not provide any information about the relationship between collagen cross-linking and the tensile modulus of articular cartilage (A)</p> Signup and view all the answers

Which region of the tensile force-deformation curve for cartilage corresponds to the straightening and un-crimping of collagen fibrils?

<p>The toe region (C)</p> Signup and view all the answers

In the linear region of the tensile force-deformation curve for cartilage, what is the behavior of the collagen fibrils?

<p>The collagen fibrils are aligned parallel to the axis of tension (A)</p> Signup and view all the answers

Which of the following factors contributes to the anisotropic mechanical behavior of cartilage?

<p>Inhomogeneous distribution of collagen fibrils and proteoglycans (C)</p> Signup and view all the answers

Under compressive loading, which of the following mechanisms contributes to the resistance of cartilage to compression?

<p>The osmotic swelling pressure increases, and the resistance to compression is achieved (B)</p> Signup and view all the answers

Which of the following statements is true regarding the tensile modulus of cartilage?

<p>The tensile modulus is higher in regions with higher collagen fibril density (C)</p> Signup and view all the answers

Which of the following factors contributes to the high compressive stiffness of cartilage?

<p>The presence of a high concentration of fixed negative charges on the proteoglycans (A)</p> Signup and view all the answers

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