Cartilage Lecture by Dr. Noor Alaa M.B.Ch.B
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Questions and Answers

What type of collagen is rich in the extracellular matrix of hyaline cartilage?

  • Type I collagen
  • Type III collagen
  • Type IV collagen
  • Type II collagen (correct)
  • In hyaline cartilage, chondrocytes can be found:

  • In large clusters
  • In isogenous groups (correct)
  • In partnership with osteoblasts
  • Attached to blood vessels
  • Which type of cartilage provides flexible support for the external ear?

  • Elastic cartilage (correct)
  • Fibrocartilage
  • Hyaline cartilage
  • Collagen cartilage
  • What is a characteristic feature of elastic cartilage that distinguishes it from hyaline cartilage?

    <p>Abundant elastic fibers</p> Signup and view all the answers

    What is the primary function of cartilage?

    <p>To provide cushioning and low-friction surfaces in joints</p> Signup and view all the answers

    How does fibrocartilage provide support in the body?

    <p>By providing very tough support</p> Signup and view all the answers

    What is the primary cell type found in cartilage?

    <p>Chondrocytes and chondroblasts</p> Signup and view all the answers

    Which of the following is NOT a major type of cartilage?

    <p>Calcified cartilage</p> Signup and view all the answers

    Which of the following statements about cartilage is true?

    <p>Cartilage is nonvascular but surrounded by a vascular perichondrium</p> Signup and view all the answers

    What is the primary function of the perichondrium?

    <p>To generate new chondrocytes for cartilage growth and repair</p> Signup and view all the answers

    Study Notes

    Cartilage Overview

    • Cartilage is a tough, resilient type of connective tissue that supports soft tissues, particularly in the respiratory tract, and provides cushioned, low-friction surfaces in joints.

    Cartilage Composition

    • Cartilage is composed mainly of chondrocytes and chondroblasts that synthesize an extensive extracellular matrix.
    • Extracellular matrix includes collagen (notably type II), proteoglycans (notably aggrecan), and a high water content.

    Cartilage Characteristics

    • Cartilage is nonvascular, but surrounded by vascular connective tissue perichondrium.
    • Nutrients enter and metabolites leave cartilage through diffusion through the matrix.

    Types of Cartilage

    Hyaline Cartilage

    • Has a homogeneous and glassy extracellular matrix rich in type II collagen and aggrecan complexes with bound water.
    • Chondrocytes occur singly or in small, mitotically derived isogenous groups.
    • Perichondrium is dense connective tissue containing chondroblasts, fibroblasts, and blood vessels.

    Elastic Cartilage

    • Has a matrix that includes abundant elastic fibers, increasing tissue flexibility.
    • Provides flexible support for the external ear, middle ear, and larynx structures.
    • Always surrounded by perichondrium.

    Fibrocartilage

    • Contains varying combinations of hyaline cartilage and dense connective tissue.
    • Histologically, it consists of small chondrocytes in a hyaline matrix, layered with bundled type I collagen and scattered fibroblasts.
    • Provides very tough, strong support at tendon insertions, intervertebral discs, and certain joints.

    Cartilage Formation, Growth, and Repair

    • All forms of cartilage form from embryonic mesenchyme.
    • Cartilaginous structures grow by mitosis of existing chondroblasts (interstitial growth) or formation of new chondroblasts peripherally from progenitor cells in the perichondrium.

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    Description

    Learn about the definition, types, formation, growth, repair, and medical applications of cartilage in this lecture by Dr. Noor Alaa M.B.Ch.B. Cartilage is a tough connective tissue that provides structural support to soft tissues and cushioned surfaces in joints.

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