5 Questions
What is the initial event that triggers the development of osteoarthritis?
Damage to articular cartilage
Which of the following is NOT a potential risk factor for osteoarthritis?
Smoking
What is the characteristic pain associated with osteoarthritis?
Localized deep, aching pain associated with the affected joint
Which joints are most commonly affected by osteoarthritis in the hands?
Distal interphalangeal (DIP) and proximal interphalangeal (PIP) joints
What is the relationship between osteoarthritis and age?
Prevalence and severity increase with age
Study Notes
- Articular cartilage damage can be caused by injury, excess loading, aging, or joint instability, leading to increased metabolic activity of chondrocytes and synthesis of matrix constituents.
- The reparative response to cartilage damage does not restore it to normal but initiates a process that can lead to further cartilage loss.
- Prevalence and severity of cartilage damage increase with age, with potential risk factors including obesity, joint trauma, and heredity.
- Common symptoms of cartilage damage include localized deep aching pain in affected joints, which worsens with joint activity and improves with rest.
- The distal interphalangeal (DIP) and proximal interphalangeal (PIP) joints of the hands are often most affected by cartilage damage.
Explore the process of cartilage damage and repair, including the causes, metabolic responses, and the likelihood of further cartilage loss. Learn about the prevalence and factors contributing to this common issue.
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