Cardiovascular System Drugs for Heart Failure I - Overview
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Questions and Answers

What are the direct detrimental effects of high levels of angiotensin II and aldosterone on cardiac muscle?

  • Favor remodeling, fibrosis, and inflammatory changes (correct)
  • Promote vasodilation and reduce natriuresis
  • Inhibit renin and aldosterone release
  • Increase myocardial contractility

    • Which natriuretic peptide is considered most important in heart failure?

  • B-type natriuretic peptide (correct)
  • D-type natriuretic peptide
  • Atrial natriuretic peptide
  • C-type natriuretic peptide

    • What does excessive elongation of heart muscle fibers lead to?

  • Improved cardiac function
  • Increased natriuresis
  • Weaker contractions and diminished ejection ability (correct)
  • Stronger contractions

    • Which term is used to describe the failure that occurs when the ventricle is unable to effectively pump blood?

    <p><strong>Heart failure with reduced ejection fraction (HFrEF)</strong></p> Signup and view all the answers

    What is a characteristic of diastolic dysfunction in patients with heart failure?

    <p><strong>Impaired ventricular relaxation and filling</strong></p> Signup and view all the answers

    Which response is activated by natriuretic peptides in heart failure?

    <p><strong>Vasodilation, natriuresis, inhibition of renin, reduction in myocardial fibrosis</strong></p> Signup and view all the answers

    What role do atrial and B-type natriuretic peptides play in heart failure?

    <p><strong>Have beneficial effects on cardiac function</strong></p> Signup and view all the answers

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