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Questions and Answers
What calculation determines the stroke volume (SV)?
What calculation determines the stroke volume (SV)?
If the end-diastolic volume (EDV) is 130 ml and the end-systolic volume (ESV) is 60 ml, what is the stroke volume (SV)?
If the end-diastolic volume (EDV) is 130 ml and the end-systolic volume (ESV) is 60 ml, what is the stroke volume (SV)?
What is the approximate cardiac output (CO) for a person with a heart rate (HR) of 75 beats per minute and a stroke volume (SV) of 80 ml?
What is the approximate cardiac output (CO) for a person with a heart rate (HR) of 75 beats per minute and a stroke volume (SV) of 80 ml?
Which of the following statement correctly describes ejection fraction?
Which of the following statement correctly describes ejection fraction?
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If a person has an end-diastolic volume (EDV) of 140 ml and a stroke volume (SV) of 70 ml, what is the ejection fraction?
If a person has an end-diastolic volume (EDV) of 140 ml and a stroke volume (SV) of 70 ml, what is the ejection fraction?
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What is primarily responsible for the initial slow depolarization phase of the pacemaker potential?
What is primarily responsible for the initial slow depolarization phase of the pacemaker potential?
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Which event causes the full depolarization phase in pacemaker cells?
Which event causes the full depolarization phase in pacemaker cells?
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What triggers the repolarization phase in pacemaker cells?
What triggers the repolarization phase in pacemaker cells?
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What causes the minimum potential phase (hyperpolarization) in pacemaker cells?
What causes the minimum potential phase (hyperpolarization) in pacemaker cells?
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Where is the sinoatrial (SA) node located?
Where is the sinoatrial (SA) node located?
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What is the intrinsic rate of depolarization of the SA node?
What is the intrinsic rate of depolarization of the SA node?
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Which of the following systems can influence the rate of depolarization of the SA node?
Which of the following systems can influence the rate of depolarization of the SA node?
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Which of the following best describes the effect of bundle branch blocks on the QRS complex?
Which of the following best describes the effect of bundle branch blocks on the QRS complex?
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The calcium ion channels in pacemaker cells are which type of gated channels?
The calcium ion channels in pacemaker cells are which type of gated channels?
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During ventricular filling, what is the relationship between the pressures in the ventricles and atria?
During ventricular filling, what is the relationship between the pressures in the ventricles and atria?
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What is the main characteristic of atrial fibrillation on an ECG tracing?
What is the main characteristic of atrial fibrillation on an ECG tracing?
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What is the immediate treatment for ventricular fibrillation?
What is the immediate treatment for ventricular fibrillation?
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What prevents the backflow of blood from the pulmonary trunk and aorta into the ventricles during ventricular filling?
What prevents the backflow of blood from the pulmonary trunk and aorta into the ventricles during ventricular filling?
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What causes the atrioventricular valves to open during the ventricular filling phase?
What causes the atrioventricular valves to open during the ventricular filling phase?
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Why is defibrillation ineffective in cases of asystole?
Why is defibrillation ineffective in cases of asystole?
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Approximately what percentage of the total atrial blood volume drains passively into the ventricles?
Approximately what percentage of the total atrial blood volume drains passively into the ventricles?
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Which condition is described as chaotic electrical activity in the ventricles, resulting in the heart’s inability to effectively pump blood?
Which condition is described as chaotic electrical activity in the ventricles, resulting in the heart’s inability to effectively pump blood?
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What is a common visual comparison used to describe the movement of a fibrillating muscle?
What is a common visual comparison used to describe the movement of a fibrillating muscle?
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What event immediately follows the end of the passive filling of the ventricles?
What event immediately follows the end of the passive filling of the ventricles?
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What is the approximate volume of blood in each ventricle at the end of atrial systole, also known as the End-Diastolic Volume (EDV)?
What is the approximate volume of blood in each ventricle at the end of atrial systole, also known as the End-Diastolic Volume (EDV)?
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What is the typical treatment for asystole, given that defibrillation is not appropriate?
What is the typical treatment for asystole, given that defibrillation is not appropriate?
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Which of the following is TRUE about atrial fibrillation?
Which of the following is TRUE about atrial fibrillation?
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What causes the S1 heart sound at the beginning of ventricular systole?
What causes the S1 heart sound at the beginning of ventricular systole?
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What characterizes the isovolumetric contraction phase?
What characterizes the isovolumetric contraction phase?
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What event is primarily responsible for the opening of the semilunar valves?
What event is primarily responsible for the opening of the semilunar valves?
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What is the approximate volume of blood remaining in each ventricle at the end of the ventricular ejection phase, also known as end-systolic volume (ESV)?
What is the approximate volume of blood remaining in each ventricle at the end of the ventricular ejection phase, also known as end-systolic volume (ESV)?
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During the isovolumetric relaxation phase, what action causes the second heart sound (S2)?
During the isovolumetric relaxation phase, what action causes the second heart sound (S2)?
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What is the state of the ventricles during the isovolumetric relaxation phase, in relation to blood volume?
What is the state of the ventricles during the isovolumetric relaxation phase, in relation to blood volume?
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If a person has a heart rate (HR) of 75 beats per minute and a stroke volume (SV) of 70 ml, what is their cardiac output (CO) in ml/min?
If a person has a heart rate (HR) of 75 beats per minute and a stroke volume (SV) of 70 ml, what is their cardiac output (CO) in ml/min?
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What is the term for the amount of blood pumped by the ventricle in one heartbeat?
What is the term for the amount of blood pumped by the ventricle in one heartbeat?
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What is the average range for the number of cardiac cycles (beats) per minute?
What is the average range for the number of cardiac cycles (beats) per minute?
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Why does the ejection of blood from the ventricles decrease as the ventricular ejection phase continues?
Why does the ejection of blood from the ventricles decrease as the ventricular ejection phase continues?
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What is the primary effect of acetylcholine release on the heart?
What is the primary effect of acetylcholine release on the heart?
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Which of the following has the strongest negative inotropic effect on the heart?
Which of the following has the strongest negative inotropic effect on the heart?
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What is the effect of epinephrine and norepinephrine on the heart?
What is the effect of epinephrine and norepinephrine on the heart?
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Which hormone decreases blood volume and preload, thereby reducing cardiac output?
Which hormone decreases blood volume and preload, thereby reducing cardiac output?
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How does an increase in body temperature affect the heart's sinoatrial (SA) node?
How does an increase in body temperature affect the heart's sinoatrial (SA) node?
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What effect does increasing blood volume have on cardiac output?
What effect does increasing blood volume have on cardiac output?
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Which of the following is a positive chronotropic agent?
Which of the following is a positive chronotropic agent?
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What is the effect of increased extracellular electrolyte concentration on cardiac output?
What is the effect of increased extracellular electrolyte concentration on cardiac output?
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Study Notes
Human Anatomy & Physiology, Chapter 17: The Cardiovascular System I: The Heart
- The cardiovascular system comprises the heart, blood vessels, and blood.
- The heart is a cone-shaped organ situated slightly left of the center in the thoracic cavity; it rests on the diaphragm and its apex points towards the left hip.
- The heart is roughly the size of a fist and weighs approximately 250-350 grams.
- The heart's superior chambers are the atria, and the inferior chambers are the ventricles.
- The atrioventricular sulcus is an indentation externally marking the boundary between the atria and ventricles.
- The interventricular sulcus is an externally visible depression separating the right and left ventricles.
- Blood enters the atria from veins and is pumped into arteries from ventricles.
- The heart has two main circuits; the pulmonary circuit, which carries blood to and from the lungs, and the systemic circuit, which carries blood to the rest of the body.
- In the pulmonary circuit, the right side of the heart pumps oxygen-poor blood to the lungs where it becomes oxygenated.
- The pulmonary arteries transfer deoxygenated blood.
- In the systemic circuit, the left side of the heart receives this oxygenated blood from the lungs and pumps it throughout the body.
- Oxygen-rich blood is carried in arteries to the tissues and oxygen-poor blood is collected in veins and returned to the heart.
- The heart has four chambers and valves that assure blood flow in only one direction.
Heart Chambers and Valves
- The heart has four chambers: two atria and two ventricles.
- The atria receive blood; the ventricles pump blood.
- The atria contract to pump blood into the ventricles, where the ventricles contract to pump blood into the arteries.
- Heart valves ensure blood flows in one direction.
- The tricuspid valve is the right AV valve; the bicuspid (mitral) valve is the left AV valve.
- Each valve has flaps called cusps that close when ventricles contract, preventing backflow.
- Semilunar valves (pulmonary valve & aortic valve) are found near where the heart pumps blood out; they prevent backflow from the arteries into the ventricles.
Blood Vessels
- Blood vessels, including arteries, veins, and capillaries, form a network to transport blood throughout the body.
- Major systemic veins include the superior and inferior vena cava, which drain blood into the right atrium.
- The pulmonary trunk receives blood from the right ventricle and branches into right and left pulmonary arteries.
- These arteries carry blood to the lungs for oxygenation.
- Oxygenated blood returns to the heart via pulmonary veins to the left atrium.
- The aorta, the largest artery in the body, receives blood from the left ventricle and distributes it to the rest of the body's systemic circuit.
The Heart's Great Vessels
- The superior vena cava (SVC) drains deoxygenated blood from the upper body.
- The inferior vena cava (IVC) drains blood from the lower body.
- The pulmonary trunk is the main vessel carrying blood from the right ventricle to the lungs.
- It branches to the right and left pulmonary arteries.
- Pulmonary veins return oxygenated blood from the lungs to the left atrium.
- The aorta receives oxygenated blood from the left ventricle and distributes it throughout the body.
The Coronary Circulation
- The heart receives blood from coronary arteries, which branch from the aorta.
- The network of channels facilitates adequate oxygen and nutrient supply to all parts of the heart tissue.
- Coronary veins collect deoxygenated blood and return it to the right atrium through the coronary sinus.
- Blockage in the coronary arteries can lead to heart attack.
Cardiac Muscle Tissue Anatomy and Electrophysiology
- The heart's rhythmic contraction arises from specialized cardiac muscle cells' autorhythmicity.
- Cardiac muscle cells exhibit unique structures called intercalated discs (desmosomes and gap junctions), contributing to coordinated contraction.
- The heart's electrical activity, orchestrated by specialized pacemaker cells, creates the heartbeat.
- The SA and AV nodes are two significant pacemaker regions, establishing the heart's rhythm.
- The Purkinje fibers disseminate the electrical signal to ensure coordinated ventricular contractions.
- An electrocardiogram (ECG) is a diagnostic tool to visualize the heart's electrical activity.
Cardiac Output and Regulation
- Cardiac output (CO) is the total blood volume pumped into circulation by the heart in one minute, determined by heart rate and stroke volume.
- Stroke volume (SV) is the amount of blood ejected by one ventricle during a contraction, dependent on preload, contractility, and afterload.
- The body regulates CO via both nervous and hormonal systems.
Heart Failure
- Heart failure is an inability for the heart to pump adequately.
- Reduced contractility, valve disease, and electrolyte imbalances contribute to heart failure.
Dysrhythmias
- Dysrhythmias or arrhythmias involve irregularities in the heart's electrical activity.
- Bradycardia denotes a slow heart rate, while tachycardia denotes a rapid heartbeat.
- Heart blocks are conduction disturbances, frequently involving the AV node, often resulting in abnormal ECG patterns
- Fibrillation, a chaotic, uncoordinated contraction of the heart muscle, may also be life threatening.
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Test your knowledge on stroke volume, cardiac output, and pacemaker potentials with this quiz. Questions cover essential calculations and physiological concepts related to heart function and the electrical conduction system. Perfect for students of cardiovascular physiology.