Podcast
Questions and Answers
Match the blood conditions with their effects on blood viscosity:
Match the blood conditions with their effects on blood viscosity:
Anemia = Decreases viscosity Polycythemia = Increases viscosity Low RBC count = Decreases TPR High RBC count = Increases MAP
Match the heart valve sounds with their corresponding events:
Match the heart valve sounds with their corresponding events:
First sound (lub) = AV valves close Second sound (dup) = Semilunar valves close Systole = Heart contraction Diastole = Heart relaxation
Match the changes in total peripheral resistance (TPR) with blood conditions:
Match the changes in total peripheral resistance (TPR) with blood conditions:
Anemia = Decreased TPR Polycythemia = Increased TPR Decreased viscosity = Decreased MAP Increased viscosity = Increased MAP
Match the terms with their definitions:
Match the terms with their definitions:
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Match the physiological processes with their outcomes:
Match the physiological processes with their outcomes:
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Match the phase of the cardiac action potential with its characteristic event:
Match the phase of the cardiac action potential with its characteristic event:
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Match the ion movement with its effect during depolarization and repolarization:
Match the ion movement with its effect during depolarization and repolarization:
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Match the mechanism with the corresponding activity during initial repolarization:
Match the mechanism with the corresponding activity during initial repolarization:
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Match the following statements with the phase they describe:
Match the following statements with the phase they describe:
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Match the concept with its role during cardiac action potentials:
Match the concept with its role during cardiac action potentials:
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Match the following phases of cardiac muscle contraction with their descriptions:
Match the following phases of cardiac muscle contraction with their descriptions:
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Match the following types of blood pressure conditions with their locations relative to the heart:
Match the following types of blood pressure conditions with their locations relative to the heart:
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Match the following statements about blood flow with their implications:
Match the following statements about blood flow with their implications:
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Match the following cardiac events with their corresponding waveforms:
Match the following cardiac events with their corresponding waveforms:
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Match the following elements of cardiac physiology with their functions:
Match the following elements of cardiac physiology with their functions:
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Match the reflex with its key description:
Match the reflex with its key description:
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Match the following components of the circulatory system with their functions:
Match the following components of the circulatory system with their functions:
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Match the blood volume change with its effect on mean arterial pressure (MAP):
Match the blood volume change with its effect on mean arterial pressure (MAP):
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Match the mechanism with its role in blood pressure regulation:
Match the mechanism with its role in blood pressure regulation:
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Match the following heart ventricles with their primary role:
Match the following heart ventricles with their primary role:
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Match the components of cardiac action potentials with their descriptions:
Match the components of cardiac action potentials with their descriptions:
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Match the physiological condition with its reflex response:
Match the physiological condition with its reflex response:
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Match the following terms with their descriptions:
Match the following terms with their descriptions:
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Match the sequence of heart contractions with the corresponding event:
Match the sequence of heart contractions with the corresponding event:
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Match the term with its correct definition:
Match the term with its correct definition:
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Match the following blood flow effects with their resulting changes:
Match the following blood flow effects with their resulting changes:
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Match the phase of cardiac action potential propagation with its speed:
Match the phase of cardiac action potential propagation with its speed:
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Match the structure with its specific function in cardiac conduction:
Match the structure with its specific function in cardiac conduction:
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Match each component with its relevant vascular network:
Match each component with its relevant vascular network:
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Match the following processes to their respective summaries:
Match the following processes to their respective summaries:
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Match the cardiac conduction sequence with its timing:
Match the cardiac conduction sequence with its timing:
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Match the following types of blood vessels with their characteristics:
Match the following types of blood vessels with their characteristics:
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Match the terms related to cardiac conduction with their correct descriptions:
Match the terms related to cardiac conduction with their correct descriptions:
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Match the heart structures with whether they primarily conduct or generate impulses:
Match the heart structures with whether they primarily conduct or generate impulses:
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Match the following concepts with their implications in blood flow:
Match the following concepts with their implications in blood flow:
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Match the arrhythmia-related terms with their meanings:
Match the arrhythmia-related terms with their meanings:
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Study Notes
Physiology (0603302)
- Course name: Physiology
- Course code: 0603302
- Chapter: Cardiac Physiology
- Semester: Summer 2023/2024
- Instructor: Dr. Mohammad A. Abedal-Majed
- Institution: The University of Jordan, School of Agriculture
Cardiac Physiology Resources
- Video (327): How does human circulatory system work – 3D animation - YouTube
- Video (328): Human Heart Anatomy And Physiology | How Human Heart works? (3D Animation) - YouTube
- Video (335): Circulatory System and Pathway of Blood Through the Heart - YouTube
Blood Flow
- Pulmonary circulation involves blood flow from the heart to the lungs, and back to the heart.
- Systemic circulation involves blood flow from the heart to the other tissues in the body, and back to the heart.
Vascular System
- Pulmonary circulation (low pressure): poorly oxygenated blood to lungs, and highly oxygenated blood to the heart.
- Systemic circulation (high pressure): highly oxygenated blood to tissues, and poorly oxygenated blood back to the heart.
Functional Components of the Circulatory System
- Pump (heart): responsible for pumping blood
- Distributing tubes (arterial system): carry blood away from the heart
- Collecting tubes (venous system): collect blood returning to the heart
- Exchange system (capillary beds): allow for exchange of substances between blood and tissues
The Pumps
- Right ventricle: pumps blood through the lungs (pulmonary circulation) acquires O2, expels CO2
- Left ventricle: pumps blood through all other tissues (systemic circulation) delivers O2 & nutrients, obtains CO2 & waste products
Distributing (arterial system) & Collecting tubes (venous system)
- Arterial system: branching of aorta & pulmonary artery; progressively smaller vessels (arteries → arterioles → capillaries)
- Venous system: empties into vena cava & pulmonary vein; smaller vessels join to form larger vessels (capillaries → venules → veins)
Exchange System (capillary beds)
- Exchange of O2, CO2, nutrients, & waste products between blood & tissues via capillaries
Cardiac Output
- CO = SV x HR
- Stroke Volume (SV): volume of blood pumped by each ventricle per beat (average 70 mL/beat)
- Heart Rate (HR): heart beats per minute (average 70 beats/min)
- Resting cardiac output: approximately 5 liters/minute
- Exercise cardiac output: can increase to 20-25 liters/minute
Heart Valves
- Atrioventricular valves: between atria and ventricles (left - mitral, right - tricuspid)
- Semilunar valves: between ventricles and major arteries (left - aortic, right - pulmonic)
Electrical Activity of Cardiac Muscle Cells
- Specialized muscle cells in the SA node spontaneously depolarize, creating an action potential.
- The action potential spreads through the heart via gap junctions.
- Pacemaker cells depolarize without neural stimulation, setting the basic heart rate.
- Motor neurons from the sympathetic and parasympathetic nervous systems modify the heart rate.
Cardiac Action Potentials
- Cardiac action potentials are relatively long (100–250 ms).
- Voltage-gated Ca2+ channels are important in prolonging these action potentials
- Phase 4 (Resting Membrane Potential): Membrane is more permeable to potassium (K+) than sodium (Na+) or calcium (Ca2+)
- Phase 0 (Depolarization): Voltage-gated sodium (Na+) channels open, causing a rapid influx of Na+
- Phase 1 (Initial Repolarization): Sodium channels inactivate, and potassium (K+) channels open, leading to a rapid outflow of K+
- Phase 2 (Plateau): Calcium channels open, causing a slow influx of Ca2+. This plateau prevents the ventricles from contracting too quickly
- Phase 3 (Repolarization): Calcium channels close, and potassium (K+) efflux accelerates, returning the membrane potential to the resting state.
- Phase 4 (Resting Membrane Potential): Voltage-gated sodium, potassium, and calcium channels close.
Cardiac Cycle
- Contraction of cardiac muscle increases ventricular chamber pressure, causing the opening of semilunar valves and the closing of atrioventricular valves.
- Relaxation of cardiac muscle decreases ventricular chamber pressure; atrioventricular valves open and semilunar valves close.
Blood Pressures
- Circulation is pressure-driven flow of blood throughout the body
- Pressures are additive when vessels are below the heart, and subtractive when above the heart
- Blood pressure values vary between a minimum (diastolic) & maximum (systolic) pressure.
- Pulse pressure = systolic pressure - diastolic pressure
- Mean arterial pressure (MAP) = diastolic pressure + (1/3) pulse pressure
Resistance & Blood Pressures
- Resistance is opposition to blood flow in a vascular bed.
- Arterioles have the highest resistance.
- Capillaries & venules have intermediate resistance.
- Veins have the lowest resistance.
Total Peripheral Resistance & Blood Pressures
- TPR= (change in pressure) / resistance
- Organ receives aortic blood
- Organ drained by vena cava
- Arteriolar diameter is what determines vascular resistance in each organ
Clinical Applications
- Blood viscosity
- Blood pressure measurement
- Electrocardiogram (ECG)
Blood Pressure Regulation
- Sympathetic nervous system: norepinephrine and epinephrine increase heart rate and contractility & cause vasoconstriction.
- Parasympathetic nervous system: acetylcholine decreases heart rates and causes vasodilation.
Baroreceptor Reflex
- Baroreceptors sense blood pressure changes
- Sends signals to the CNS for control (sympathetic, parasympathetic effect
- This reflex helps restore normal blood pressures.
Atrial Volume Receptor Reflex
- Atrial volume receptors sense blood volume
- Sends signals to the CNS for control (hormonal, nervous system effects
- This reflex helps restore normal blood volume.
Blood Pressure & RAAS
- Renin-angiotensin-aldosterone system (RAAS) is activated by reduced blood pressure and low blood volume
- RAAS, promotes sodium and water reabsorption in the kidneys, increasing blood volume and pressure.
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Description
Test your understanding of cardiovascular physiology by matching key terms, conditions, and physiological processes with their effects or definitions. This quiz covers various aspects of blood viscosity, heart valve sounds, total peripheral resistance, and cardiac action potentials. Perfect for students studying anatomy or physiology.