Cardiovascular Medications and Interactions
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Questions and Answers

What is the primary concern when using ACEs and ARBs?

  • Hypertension
  • Tachycardia
  • Hypokalemia
  • Angioedema (correct)
  • What is the combination medication Entresto used to treat?

  • Heart failure (correct)
  • Pulmonary edema
  • Chronic kidney disease
  • Hypertension
  • Which diuretic is commonly used to treat pulmonary edema in patients who are struggling to breathe?

  • Furosemide (correct)
  • HCTZ
  • Spironolactone
  • Bumetanide
  • What is the top issue associated with the use of furosemide?

    <p>Hypokalemia</p> Signup and view all the answers

    What is the complication of taking digoxin with a diuretic, especially one that lowers potassium levels?

    <p>Both hypo and hyperkalemia</p> Signup and view all the answers

    What is the name of the potassium-sparing diuretic?

    <p>Spironolactone</p> Signup and view all the answers

    What is the calculation required to determine the volume of bumetanide to administer via IV push?

    <p>Prescribed dose in mg divided by concentration in mg/mL</p> Signup and view all the answers

    What is a common side effect of thiazide diuretics?

    <p>Increased sensitivity to sunlight</p> Signup and view all the answers

    What is the main purpose of blocking the RAAS system in hypertension treatment?

    <p>To decrease blood pressure through vasodilation and diuresis</p> Signup and view all the answers

    What is a common side effect of ACE inhibitors?

    <p>All of the above</p> Signup and view all the answers

    Which medication would NOT need to be held for a client with a potassium level of 6.2 mEq/L?

    <p>None of the above</p> Signup and view all the answers

    What is the mechanism of action of -glutides in the treatment of diabetes?

    <p>Mimicking the action of incretin</p> Signup and view all the answers

    What is a risk associated with the use of -glutides and -gliptins?

    <p>Pancreatitis</p> Signup and view all the answers

    Which suffix is associated with ACE inhibitors?

    <p>-pril</p> Signup and view all the answers

    What is the effect of vasodilation on blood pressure?

    <p>It decreases blood pressure</p> Signup and view all the answers

    Why is it important to know about the RAAS system in hypertension treatment?

    <p>To understand how to decrease blood pressure</p> Signup and view all the answers

    Which medication is known for its vasodilating properties and primarily acts on the body system related to peripheral arterial resistance?

    <p>Hydralazine</p> Signup and view all the answers

    Which of the following medications primarily serves as a vasodilator due to its mechanism of action on angiotensin II receptors?

    <p>Losartan</p> Signup and view all the answers

    What is the mechanism of action of Lisinopril in terms of its effect on the body system?

    <p>Angiotensin-converting enzyme inhibition</p> Signup and view all the answers

    Which medication among the following is classified as a potassium-sparing diuretic and can also result in vasodilation?

    <p>Spironolactone</p> Signup and view all the answers

    Which beta-blocker specifically allows for vasodilation and is noted for its additional effects in congestive heart failure?

    <p>Carvedilol</p> Signup and view all the answers

    What should patients taking Terazosin be cautioned about regarding its effects as a vasodilator?

    <p>Occurrence of orthostatic hypotension</p> Signup and view all the answers

    Which of the following statements correctly describes the unique property of Amlodipine as a vasodilator?

    <p>It is a dihydropyridine calcium channel blocker</p> Signup and view all the answers

    Which of the following anti-hypertensive medications is most likely to cause a feeling of dry mouth as a side effect?

    <p>Clonidine</p> Signup and view all the answers

    Study Notes

    Cardio Drugs and Grapefruit Interaction

    • Statins and amiodarone are cardio drugs that show a dangerous increased effect when taken with grapefruit.

    Anti-Hypertensive Medications

    • Clonidine works on the central nervous system.
    • Metoprolol is a beta blocker that works on the cardiac system and is a vasodilator.
    • Hydrochlorothiazide is a diuretic that works on the renal system.
    • Hydralazine is a vasodilator that works on the peripheral nervous system.
    • Losartan is an angiotensin receptor blocker that works on the renal system.
    • Lisinopril is an ACE inhibitor that works on the renal system.
    • Spironolactone is a potassium-sparing diuretic that works on the renal system.
    • Terazosin is an alpha blocker that works on the peripheral nervous system.
    • Amlodipine is a calcium channel blocker that works on the peripheral nervous system.

    Beta Blockers

    • Beta 1 (B1) blocking is cardiac-specific, while beta 2 (B2) blocking is bronchial-specific.
    • Carvedilol, metoprolol, and timolol are examples of beta blockers.
    • Beta blockers mask hypoglycemia tachycardia.

    Clonidine

    • Clonidine is used to treat high blood pressure and ADHD.
    • Common side effects of clonidine include dry mouth, drowsiness, and tachycardia.

    ACE Inhibitors and ARBs

    • ACE inhibitors and ARBs are high-risk medications for the elderly (Beers).
    • Priority side effect of ACEs and ARBs is angioedema, which can cause breathing difficulties.
    • Entresto is a combination medication used to treat heart failure with reduced ejection fraction.

    Diuretics

    • Diuretics are used to treat pulmonary edema, a common exacerbation of heart failure.
    • Furosemide is a loop diuretic that can cause hypokalemia, decreased blood pressure, and ototoxicity.
    • Bumetanide is a loop diuretic that is used to treat pulmonary edema.
    • Thiazide diuretics, such as HCTZ and chlorthalidone, can cause increased sensitivity to sunlight.
    • Spironolactone is a potassium-sparing diuretic.

    Hormones and Diabetes

    • Incretin and amylin are hormones that need to be blocked in the treatment of diabetes.
    • The -gliptins, such as sitagliptin, work through the gut and have unique side effects, including joint pain and pancreatitis.
    • The -glutides, such as exenatide, work like incretin and have side effects, including pancreatitis, thyroid risk, and appetite suppression.

    Hypoglycemia

    • Hypoglycemia can be masked by certain medications, including beta blockers.
    • Signs of hypoglycemia include increased heart rate, sweating, and confusion.
    • Treatment for hypoglycemia includes administering glucose or glucagon.

    Ketoacidosis

    • Ketoacidosis occurs when blood glucose is too high or too low, typically in type 1 diabetes.
    • Ketoacidosis requires immediate treatment to prevent complications.

    RAAS System

    • The renin-angiotensin-aldosterone system (RAAS) increases blood pressure by causing vasoconstriction and fluid retention.
    • Medications can be used to block or inhibit the RAAS system to treat hypertension and fluid retention.

    Medication Suffixes

    • The -pril suffix indicates an ACE inhibitor, while the -sartan suffix indicates an ARB.

    Potassium Levels

    • For a client with a potassium level of 6.2 mEq/L, medications such as captopril, losartan, and spironolactone would need to be held.

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    Description

    This quiz covers the effects of grapefruit on cardio drugs, the handling of extended release medications, and the mechanism of action of anti-hypertensive medications.

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