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What is a critical nursing intervention when administering calcium channel blockers to patients?
What is a critical nursing intervention when administering calcium channel blockers to patients?
Patients should be instructed to report dizziness and symptoms of an irregular heart rate.
Why should patients avoid grapefruit juice while taking calcium channel blockers?
Why should patients avoid grapefruit juice while taking calcium channel blockers?
Grapefruit juice inhibits the hepatic metabolism of calcium channel blockers, potentially leading to increased drug levels.
How do azole antifungals and certain antibiotics affect the metabolism of cardiovascular agents?
How do azole antifungals and certain antibiotics affect the metabolism of cardiovascular agents?
They can inhibit drug metabolism, leading to elevated levels and potentially increased effects or toxicity.
What precautions should be taken for patients with heart failure when prescribing calcium channel blockers?
What precautions should be taken for patients with heart failure when prescribing calcium channel blockers?
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What are common adverse effects of beta blockers that a nurse should monitor?
What are common adverse effects of beta blockers that a nurse should monitor?
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What is the impact of combining statins with calcium channel blockers?
What is the impact of combining statins with calcium channel blockers?
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List one class of medications that should be monitored for interaction due to their effect on cytochrome P450 isoenzymes.
List one class of medications that should be monitored for interaction due to their effect on cytochrome P450 isoenzymes.
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In managing patients with Prinzmetal angina, how do calcium channel blockers provide therapeutic benefits?
In managing patients with Prinzmetal angina, how do calcium channel blockers provide therapeutic benefits?
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What physical assessments should a nurse perform to evaluate perfusion when administering phosphodiesterase inhibitors?
What physical assessments should a nurse perform to evaluate perfusion when administering phosphodiesterase inhibitors?
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Why are phosphodiesterase inhibitors contraindicated in patients with severe aortic or pulmonic valvular disease?
Why are phosphodiesterase inhibitors contraindicated in patients with severe aortic or pulmonic valvular disease?
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What laboratory tests should be monitored during the administration of drugs like inamrinone and milrinone?
What laboratory tests should be monitored during the administration of drugs like inamrinone and milrinone?
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What is the onset and peak time of intravenous inamrinone and milrinone administration?
What is the onset and peak time of intravenous inamrinone and milrinone administration?
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Describe the significance of obtaining a baseline ECG before administering phosphodiesterase inhibitors.
Describe the significance of obtaining a baseline ECG before administering phosphodiesterase inhibitors.
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What is the primary route of administration for inamrinone and milrinone, and why is it used?
What is the primary route of administration for inamrinone and milrinone, and why is it used?
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What can a nurse assess in a patient’s abdomen to gauge gastrointestinal motility when administering these medications?
What can a nurse assess in a patient’s abdomen to gauge gastrointestinal motility when administering these medications?
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What are the primary metabolites of inamrinone and milrinone, and how are they excreted?
What are the primary metabolites of inamrinone and milrinone, and how are they excreted?
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What nursing considerations should be taken when administering calcium channel blockers (CCBs) to patients with coronary artery disease (CAD)?
What nursing considerations should be taken when administering calcium channel blockers (CCBs) to patients with coronary artery disease (CAD)?
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How does the metabolism of amlodipine get affected by certain drug interactions?
How does the metabolism of amlodipine get affected by certain drug interactions?
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What are the key patient responses to monitor after administering nitrates for angina pectoris?
What are the key patient responses to monitor after administering nitrates for angina pectoris?
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What contraindications exist for the use of bile acid sequestrants?
What contraindications exist for the use of bile acid sequestrants?
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How can the combination of calcium channel blockers and beta-blockers affect a patient's heart rate and blood pressure?
How can the combination of calcium channel blockers and beta-blockers affect a patient's heart rate and blood pressure?
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What should nurses monitor for in patients taking cholestyramine to manage cholesterol levels?
What should nurses monitor for in patients taking cholestyramine to manage cholesterol levels?
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What is the significance of recognizing symptoms of ischemic heart disease in patients treated with cardiovascular agents?
What is the significance of recognizing symptoms of ischemic heart disease in patients treated with cardiovascular agents?
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Why is it essential to assess the patient's response to treatment when using CCBs for atrial fibrillation?
Why is it essential to assess the patient's response to treatment when using CCBs for atrial fibrillation?
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Study Notes
Calcium Channel Blockers
- Decrease calcium influx into smooth muscle
- Cause vascular relaxation
- Reverse or prevent coronary vessel spasms
- Used for conditions such as angina, hypertension, supraventricular tachycardia
- Effective for coronary artery spasms
- Three classes: phenylalkylamines, benzothiazepines, and dihydropyridines
- Common examples: verapamil, diltiazem, and amlodipine
Interactions
- Azole antifungals, clarithromycin, erythromycin, and HIV drugs can increase levels and effects of calcium channel blockers
- Statins can increase statin toxicity
- Cyclosporine can cause possible toxicity of either drug
- Grapefruit juice inhibits metabolism, leading to higher blood levels and stronger effects
Nursing Considerations
- Tell patients to report dizziness and symptoms of an irregular heart rate
- Warn patients to avoid grapefruit juice
- Use cautiously in patients with heart failure
- Monitor skin and mucous membranes, nail beds, and capillary refill
- Examine abdomen for distention and auscultate bowel sounds
- Assess voiding patterns and urinary output
- Obtain baseline ECG to evaluate rate and rhythm
- Monitor laboratory tests, including serum electrolytes, complete blood count, and renal and hepatic function tests
Phosphodiesterase Inhibitors
- Contraindicated in allergies to the drugs or bisulfites
- Contraindicated in severe aortic or pulmonic valvular disease
- Distributed after injection or rapid GI absorption
- Excreted in urine
Bile Acid Sequestrants
- Act while in the intestine
- Excreted directly in feces
- Cholestyramine must be mixed with liquids
- Colestipol is available in powder and tablet form
- Colesevelam is available in tablet form
- Contraindicated in allergies to bile acid sequestrants
- Contraindicated in complete biliary obstruction
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Description
This quiz covers the fundamentals of calcium channel blockers, including their mechanisms, interactions, and nursing considerations. Test your knowledge on the different classes of these medications and their uses in treating conditions like angina and hypertension.