Cardiovascular Disease and Thrombosis Quiz

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Which factor is responsible for the formation of a hemostatic plug that seals the vessel wall and prevents further blood loss?

Tissue plasminogen activator evaluation

Fibrinolysis facilitation

Platelet adherence (correct)

Activation of the coagulation cascade

What is responsible for enhancing platelet aggregation in the coagulation cascade?

Fibrin production

Factors V and VIII activation

Thrombin (correct)

Tissue plasminogen activator

Which condition is associated with venous stasis?

Pregnancy/postpartum

Excess of factor VIII or XI

Indwelling venous catheters

Heart failure (correct)

What is the FDA-approved use of Warfarin?

Prevention and treatment of VTE Signup and view all the answers

Which mechanism does Warfarin use to exert its anticoagulant effect?

Inhibiting production of clotting factors II, VII, IX, X, proteins C and S Signup and view all the answers

What is a contraindication for Warfarin therapy?

Pregnancy/postpartum Signup and view all the answers

Which cellular materials compose a thrombus?

Red and white blood cells, platelets Signup and view all the answers

What is the common manifestation of clot formation in the venous circulation?

Pulmonary embolism (PE) Signup and view all the answers

Which factor does Unfractionated heparin (UFH) inhibit to prevent clot formation?

Factor IIa (thrombin) Signup and view all the answers

What condition is a contraindication for the use of Unfractionated heparin (UFH)?

Severe thrombocytopenia Signup and view all the answers

What should be done if major bleeding occurs during Unfractionated heparin (UFH) therapy?

Discontinue therapy immediately and start IV protamine sulfate infusion over 10 minutes Signup and view all the answers

What does heparin-induced inhibition of thrombin-induced activation of factor VIII result in?

Inhibition of further clot formation Signup and view all the answers

Cardiovascular Disease and Thrombosis Quiz

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Questions and Answers

Which factor is responsible for the formation of a hemostatic plug that seals the vessel wall and prevents further blood loss?

What is responsible for enhancing platelet aggregation in the coagulation cascade?

Which condition is associated with venous stasis?

What is the FDA-approved use of Warfarin?

Which mechanism does Warfarin use to exert its anticoagulant effect?

What is a contraindication for Warfarin therapy?

Which cellular materials compose a thrombus?

What is the common manifestation of clot formation in the venous circulation?

Which factor does Unfractionated heparin (UFH) inhibit to prevent clot formation?

What condition is a contraindication for the use of Unfractionated heparin (UFH)?

What should be done if major bleeding occurs during Unfractionated heparin (UFH) therapy?

What does heparin-induced inhibition of thrombin-induced activation of factor VIII result in?

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