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What is the term for the group of medical conditions that affect the functioning of the heart and blood vessels?
What is the term for the group of medical conditions that affect the functioning of the heart and blood vessels?
Cardiovascular disease (CVD)
What is the name of the disease that affects the arteries that supply the heart and often leads to heart attack?
What is the name of the disease that affects the arteries that supply the heart and often leads to heart attack?
Coronary artery disease (CAD) or heart disease
What is the term for the abnormal functioning of the carotid arteries in the neck that provide blood to the brain?
What is the term for the abnormal functioning of the carotid arteries in the neck that provide blood to the brain?
Carotid artery disease
How does COVID-19 pose an increased risk of heart attack in people with cardiovascular disease?
How does COVID-19 pose an increased risk of heart attack in people with cardiovascular disease?
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What is the term for the chronic condition in which the blood pressure in the arteries is elevated?
What is the term for the chronic condition in which the blood pressure in the arteries is elevated?
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What is the name of the disease that affects the arteries that supply the arms and legs (limbs) and pelvic region?
What is the name of the disease that affects the arteries that supply the arms and legs (limbs) and pelvic region?
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What is atherosclerosis, and what is the process by which it occurs?
What is atherosclerosis, and what is the process by which it occurs?
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What is the difference between HDL and LDL cholesterol in relation to cardiovascular health?
What is the difference between HDL and LDL cholesterol in relation to cardiovascular health?
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What is the term for a thrombus or part of a plaque that breaks free from where it formed and travels through the bloodstream?
What is the term for a thrombus or part of a plaque that breaks free from where it formed and travels through the bloodstream?
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In which arteries is the blood supply vulnerable to damage by atherosclerosis?
In which arteries is the blood supply vulnerable to damage by atherosclerosis?
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What is the result of atherosclerosis in the carotid arteries in the neck?
What is the result of atherosclerosis in the carotid arteries in the neck?
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Why does atherosclerosis contribute to the development of hypertension?
Why does atherosclerosis contribute to the development of hypertension?
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What is the role of lipoproteins in the development of atherosclerosis?
What is the role of lipoproteins in the development of atherosclerosis?
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What type of lipoprotein is the largest and least dense?
What type of lipoprotein is the largest and least dense?
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What is the leading cause of death in the United States, and what percentage of deaths is it responsible for?
What is the leading cause of death in the United States, and what percentage of deaths is it responsible for?
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What is the function of HDL in the bloodstream?
What is the function of HDL in the bloodstream?
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What is the function of LDL in the bloodstream?
What is the function of LDL in the bloodstream?
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What is atherosclerosis, and how does it affect the functioning of arteries?
What is atherosclerosis, and how does it affect the functioning of arteries?
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Why is the 'good' or 'bad' classification of cholesterol no longer helpful in predicting a person's risk of atherosclerosis?
Why is the 'good' or 'bad' classification of cholesterol no longer helpful in predicting a person's risk of atherosclerosis?
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What is the role of inflammation in the development of atherosclerosis?
What is the role of inflammation in the development of atherosclerosis?
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What is the difference between a healthy artery and an atherosclerotic artery?
What is the difference between a healthy artery and an atherosclerotic artery?
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What is the result of hypertension on the heart?
What is the result of hypertension on the heart?
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What is a thrombus, and how does it affect blood flow?
What is a thrombus, and how does it affect blood flow?
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What is the result of a thrombus completely blocking blood flow to a section of the heart muscle?
What is the result of a thrombus completely blocking blood flow to a section of the heart muscle?
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What is the effect of a thrombus blocking an artery in the brain?
What is the effect of a thrombus blocking an artery in the brain?
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What is the result of a thrombus blocking an artery in a limb?
What is the result of a thrombus blocking an artery in a limb?
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Why is it essential for blood to clot, especially when blood vessels have been injured?
Why is it essential for blood to clot, especially when blood vessels have been injured?
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What is the relationship between COVID-19 and cardiovascular disease?
What is the relationship between COVID-19 and cardiovascular disease?
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What is the primary reason why oxidized LDL cholesterol is harmful to the body?
What is the primary reason why oxidized LDL cholesterol is harmful to the body?
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How does cigarette smoking contribute to the development of atherosclerosis?
How does cigarette smoking contribute to the development of atherosclerosis?
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What is the effect of oxidized HDL cholesterol on cardiovascular health?
What is the effect of oxidized HDL cholesterol on cardiovascular health?
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What is the primary difference between VLDL and LDL in terms of their lipid composition?
What is the primary difference between VLDL and LDL in terms of their lipid composition?
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What is the effect of excessive alcohol and refined carbohydrate intake on VLDL production?
What is the effect of excessive alcohol and refined carbohydrate intake on VLDL production?
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According to the National Heart, Lung, and Blood Institute, what is the significance of having multiple risk factors for atherosclerosis?
According to the National Heart, Lung, and Blood Institute, what is the significance of having multiple risk factors for atherosclerosis?
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What is the age at which men and women are more likely to develop atherosclerosis?
What is the age at which men and women are more likely to develop atherosclerosis?
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How does a person's genetic makeup influence their risk of atherosclerosis?
How does a person's genetic makeup influence their risk of atherosclerosis?
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What is the significance of oxidized LDL cholesterol in the development of atherosclerosis?
What is the significance of oxidized LDL cholesterol in the development of atherosclerosis?
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Why is having a high level of HDL cholesterol not necessarily a sign of good cardiovascular health?
Why is having a high level of HDL cholesterol not necessarily a sign of good cardiovascular health?
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What is the role of B vitamins in relation to homocysteine?
What is the role of B vitamins in relation to homocysteine?
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What is the association between homocysteine and cardiovascular disease?
What is the association between homocysteine and cardiovascular disease?
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Why is hypertension referred to as a 'silent disease'?
Why is hypertension referred to as a 'silent disease'?
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How does excess body fat, particularly in the abdominal region, contribute to cardiovascular disease?
How does excess body fat, particularly in the abdominal region, contribute to cardiovascular disease?
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What is the impact of tobacco use on cardiovascular disease?
What is the impact of tobacco use on cardiovascular disease?
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Why is it important to modify lifestyle choices to reduce the risk of atherosclerosis?
Why is it important to modify lifestyle choices to reduce the risk of atherosclerosis?
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What is the association between metabolic syndrome and cardiovascular disease?
What is the association between metabolic syndrome and cardiovascular disease?
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How does sodium intake contribute to the development of hypertension?
How does sodium intake contribute to the development of hypertension?
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What is the impact of elevated blood lipids on cardiovascular disease?
What is the impact of elevated blood lipids on cardiovascular disease?
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Why is it crucial to address modifiable risk factors for atherosclerosis?
Why is it crucial to address modifiable risk factors for atherosclerosis?
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What is the primary component of e-liquids that can contribute to atherosclerosis and poor cardiovascular health?
What is the primary component of e-liquids that can contribute to atherosclerosis and poor cardiovascular health?
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How does emotional stress contribute to the development of atherosclerosis?
How does emotional stress contribute to the development of atherosclerosis?
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What is the main difference between a risk factor and a cause of disease, as seen in the context of atherosclerosis?
What is the main difference between a risk factor and a cause of disease, as seen in the context of atherosclerosis?
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Why is it important to fast for 12 hours before a lipoprotein profile test?
Why is it important to fast for 12 hours before a lipoprotein profile test?
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What is the desirable range for total cholesterol in mg/dl, according to Table 6.5?
What is the desirable range for total cholesterol in mg/dl, according to Table 6.5?
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What is the primary purpose of regular medical checkups in assessing the risk of atherosclerosis?
What is the primary purpose of regular medical checkups in assessing the risk of atherosclerosis?
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What is the difference between serum and plasma in the context of medical testing?
What is the difference between serum and plasma in the context of medical testing?
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Why is it important to understand the complexity of atherosclerosis and its multiple risk factors?
Why is it important to understand the complexity of atherosclerosis and its multiple risk factors?
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What is the primary way to assess whether the carotid arteries are becoming blocked during a medical checkup?
What is the primary way to assess whether the carotid arteries are becoming blocked during a medical checkup?
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Why is it important to reduce or eliminate modifiable risk factors for atherosclerosis?
Why is it important to reduce or eliminate modifiable risk factors for atherosclerosis?
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Study Notes
Cardiovascular Disease (CVD)
- CVD is a group of medical conditions that affect the functioning of the heart and blood vessels
- Some forms of CVD are the result of birth defects, inherited conditions, and infections
- Includes coronary artery disease (CAD), carotid artery disease, peripheral artery disease (PAD), and chronic high blood pressure (hypertension)
Atherosclerosis
- A chronic process that negatively affects the functioning of arteries
- Results from the deposit of cholesterol and other substances in the arterial walls, leading to the formation of plaques
- Plaques can rupture, causing blood clots to form, which can lead to heart attack or stroke
- Contributes to the development of hypertension, a major risk factor for heart disease and stroke
Lipoproteins and Atherosclerosis
- Lipoproteins transport cholesterol and triglycerides in the bloodstream
- Three major types of lipoproteins: chylomicrons, high-density lipoprotein (HDL), and low-density lipoprotein (LDL)
- HDL is the smallest and densest lipoprotein, transports cholesterol away from tissues and to the liver for processing and elimination
- LDL transports cholesterol to tissues, where it can be used to make cell structures and vital compounds
- Oxidized LDL cholesterol is taken up by plaque-forming arterial cells, contributing to atherosclerosis
Risk Factors for Atherosclerosis
- Modifiable risk factors:
- Unhealthy diet
- Hypertension
- Insulin resistance and diabetes
- Elevated blood cholesterol (especially LDL cholesterol)
- Excess body fat
- Physical inactivity
- Tobacco use or exposure to tobacco smoke
- Nonmodifiable risk factors:
- Family history of CVD
- Increasing age
- Other risk factors:
- Homocysteine levels (associated with CVD)
- Genetics (family history)
- Emotional stress (particularly anger)
Reducing the Risk of Atherosclerosis
- Modifying lifestyle choices can reduce the risk of atherosclerosis
- Avoiding tobacco use, limiting intake of saturated fat, exercising regularly, and maintaining a healthy body weight can all help reduce the risk
- Reducing sodium intake, managing diabetes, and maintaining healthy blood pressure can also help reduce the risk### Diet and Atherosclerosis
- Diet influences the likelihood of atherosclerosis and is highly modifiable.
Medical Testing for Atherosclerosis
- Regular medical checkups can determine the risk of atherosclerosis.
- Blood pressure and blood flow in carotid arteries are checked to assess artery blockage.
- A lipoprotein profile is requested to assess:
- Total serum cholesterol level
- Serum HDL cholesterol level
- Serum LDL cholesterol level
- Triglyceride levels
Blood Lipoprotein Levels
- Blood lipoprotein levels increase after consuming foods and beverages.
- Levels can remain elevated for a few hours.
- To obtain accurate information, individuals should fast for 12 hours before blood is drawn for a lipoprotein profile.
Classification of Fasting Blood Lipid Levels
- "Desirable" (low risk) range for total cholesterol is less than 200 mg/dl.
- Average total blood cholesterol level in American adults (2013-2016): 191 mg/dl.
- Approximately 12% of adults have blood cholesterol levels ≥ 240 mg/dl, placing them at high risk of cardiovascular disease.
- Classification of fasting blood lipid levels:
- Total cholesterol:
- < 200 mg/dl: desirable
- 200-239 mg/dl: borderline high
- ≥ 240 mg/dl: high risk
- LDL cholesterol:
- < 100 mg/dl: optimal
- 100-129 mg/dl: near optimal
- 130-159 mg/dl: borderline high
- ≥ 160 mg/dl: high risk
- HDL cholesterol:
- ≥ 60 mg/dl: high
- 40-59 mg/dl: average
- < 40 mg/dl: low
- Triglycerides:
- < 150 mg/dl: normal
- 150-199 mg/dl: borderline high
- ≥ 200 mg/dl: high risk
- Total cholesterol:
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Description
Learn about Cardiovascular Disease (CVD), its forms and causes, as well as Atherosclerosis, a chronic process affecting arteries. Quiz covers coronary artery disease, carotid artery disease, peripheral artery disease, and hypertension.