Podcast
Questions and Answers
What is the primary cause of imbalance between oxygen demand and oxygen supply in the myocardium?
What is the primary cause of imbalance between oxygen demand and oxygen supply in the myocardium?
- Coronary artery spasm
- Hypertension
- Atherosclerotic plaque formation (correct)
- Diabetes mellitus
Which of the following is NOT a clinical entity of Acute Coronary Syndrome?
Which of the following is NOT a clinical entity of Acute Coronary Syndrome?
- ST-segment elevation myocardial infarction (STEMI)
- Chronic stable angina (correct)
- Non-ST segment elevation myocardial infarction (N-STEMI)
- Unstable angina
Which risk factor for ischemic heart disease is familial?
Which risk factor for ischemic heart disease is familial?
- Hypertension
- Smoking
- Obesity
- Familial hypercholesterolemia (correct)
What is the term for the blockage of a coronary artery, leading to myocardial infarction?
What is the term for the blockage of a coronary artery, leading to myocardial infarction?
Which of the following is a modifiable risk factor for ischemic heart disease?
Which of the following is a modifiable risk factor for ischemic heart disease?
Study Notes
Ischemic Heart Disease
- Inadequate perfusion of the myocardium due to imbalance between oxygen demand and oxygen supply
- Pathogenesis: narrowing/occlusion of coronary artery most commonly due to atheromatous plaque formation
Acute Coronary Syndrome (ACS)
- Spectrum of coronary artery disease that includes three clinical entities:
- Unstable angina
- Non-ST segment elevation myocardial infarction (N-STEMI)
- ST-segment elevation myocardial infarction (STEMI)
- Pathogenesis: rupture of an atherosclerotic plaque and partial or complete thrombosis of a coronary artery
Risk Factors for Ischemic Heart Disease/Atherosclerosis
Non-Modifiable Risk Factors
- Age > 50 years
- Sex: more common in males
- Family history of ischemic heart disease
- Familial hypercholesterolemia
Modifiable Risk Factors
- Obesity and physical inactivity
- Smoking and psychic stress
- Diabetes mellitus
- Hypertension
- Dyslipidemia
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Description
Learn about the pathogenesis of acute coronary syndrome, including unstable angina, non-ST segment elevation myocardial infarction, and ST-segment elevation myocardial infarction. Understand the imbalance between oxygen demand and oxygen supply in the myocardium.
