Podcast
Questions and Answers
What was the best cutoff value for fractional flow reserve?
What was the best cutoff value for fractional flow reserve?
- IVUS-ALM of 2.3 mm2
- OCT-area of stenosis of 65.0%
- IVUS-ALM of 3.8 mm2 (correct)
- OCT-ALM of 2.3 mm2
What was the percentage of plaque burden for OCT-ALM?
What was the percentage of plaque burden for OCT-ALM?
- 60.0%
- 70.0%
- 65.0% (correct)
- 75.0%
What was the diagnostic accuracy of anatomical parameters?
What was the diagnostic accuracy of anatomical parameters?
- Low, below 50%
- Moderate, around 70-80% (correct)
- High, above 90%
- Moderate, around 50-60%
What was the correlation between physiological indices and anatomical parameters?
What was the correlation between physiological indices and anatomical parameters?
Which test was used to measure fractional flow reserve?
Which test was used to measure fractional flow reserve?
What was the discriminative power of physiological indices?
What was the discriminative power of physiological indices?
What was the clinical trial identifier for this study?
What was the clinical trial identifier for this study?
Who published this study?
Who published this study?
What is a limitation of coronariography?
What is a limitation of coronariography?
What is an invasive physiological index used to guide clinical decisions?
What is an invasive physiological index used to guide clinical decisions?
What is used to evaluate coronary arteries in addition to coronariography?
What is used to evaluate coronary arteries in addition to coronariography?
What is the significance of the discrepancy between angiographic stenosis intensity and myocardial ischemia?
What is the significance of the discrepancy between angiographic stenosis intensity and myocardial ischemia?
What is the purpose of using invasive physiological indices?
What is the purpose of using invasive physiological indices?
Where was the study conducted?
Where was the study conducted?
What is the time period during which the study was conducted?
What is the time period during which the study was conducted?
How many coronary arteries were evaluated using IVUS or OCT?
How many coronary arteries were evaluated using IVUS or OCT?
What is the purpose of intracoronary imaging diagnostic techniques?
What is the purpose of intracoronary imaging diagnostic techniques?
What was excluded from the study?
What was excluded from the study?
What was the goal of previous studies?
What was the goal of previous studies?
What was the limitation of previous studies?
What was the limitation of previous studies?
What was the criterion for performing intravascular imaging exploration?
What was the criterion for performing intravascular imaging exploration?
What was the purpose of the specific protocol for this analysis?
What was the purpose of the specific protocol for this analysis?
What was the relationship between the population of patients and the quantitative parameters?
What was the relationship between the population of patients and the quantitative parameters?
What was the factor that influenced the diagnostic value of the quantitative parameters?
What was the factor that influenced the diagnostic value of the quantitative parameters?
What was calculated from each wave with an offline algorithm?
What was calculated from each wave with an offline algorithm?
What was standardized before RFR calculation?
What was standardized before RFR calculation?
What was applied to eliminate subcycle artifacts?
What was applied to eliminate subcycle artifacts?
What was defined as the point with the lowest Pa/Pd ratio?
What was defined as the point with the lowest Pa/Pd ratio?
How many cardiac cycles were required for RFR determination?
How many cardiac cycles were required for RFR determination?
What was calculated as the average of the Pd/Pa ratio?
What was calculated as the average of the Pd/Pa ratio?
What was used to measure coronary physiological parameters?
What was used to measure coronary physiological parameters?
Where was the algorithm used for RFR calculation developed?
Where was the algorithm used for RFR calculation developed?
What is the role of intravascular ultrasound in coronary stenosis?
What is the role of intravascular ultrasound in coronary stenosis?
What is the purpose of fractional flow reserve?
What is the purpose of fractional flow reserve?
What is the correlation between physiological indices and anatomical parameters?
What is the correlation between physiological indices and anatomical parameters?
What is the purpose of intravascular ultrasound-derived minimal lumen area?
What is the purpose of intravascular ultrasound-derived minimal lumen area?
What is the role of quantitative computed tomography in coronary stenosis?
What is the role of quantitative computed tomography in coronary stenosis?
What is the purpose of head-to-head comparison of quantitative coronary angiography and quantitative computed tomography?
What is the purpose of head-to-head comparison of quantitative coronary angiography and quantitative computed tomography?
What is the significance of minimal lumen area in left main coronary artery stenosis?
What is the significance of minimal lumen area in left main coronary artery stenosis?
What is the purpose of the study mentioned in the text?
What is the purpose of the study mentioned in the text?
Study Notes
Coronary Artery Disease Diagnosis
- Fractional flow reserve (FFR) is used to guide clinical decisions regarding revascularization.
- Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are intracoronary imaging techniques that provide accurate anatomical information.
- Physiological indices like FFR and instantaneous wave-free ratio (iFR) are used to predict functional significance of coronary stenosis.
Study Design and Population
- The study included consecutive patients who underwent invasive coronary angiography for clinical indication.
- IVUS or OCT examination of at least one coronary artery was performed.
- Patients with hemodynamic instability, left ventricular dysfunction, or acute coronary syndrome were excluded.
Parameters and Measurements
- FFR was calculated using an offline algorithm (Abbott Vascular, Santa Clara, CA, USA) with a standardized sampling frequency of 100 Hz.
- The pressure wire was used to measure the pressure curves.
- The minimal lumen diameter, reference vessel diameter, and lesion length were measured.
- The SYNTAX score was determined according to previously published methods.
Key Findings
- The best cut-off values for fractional flow reserve were IVUS-ALM of 3.8 mm², plaque burden of 70.0%, OCT-ALM of 2.3 mm², and OCT stenosis area of 65.0%.
- Physiological indices at rest showed an identical correlation with quantitative plaque characteristics defined by IVUS or OCT.
- Fractional flow reserve showed a stronger correlation with IVUS or OCT parameters than physiological indices at rest.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz assesses your understanding of the best cut-off values for fractional flow reserve, including IVUS-ALM, OCT-ALM, and OCT-area of stenosis. It covers the predictive accuracy of diagnostic parameters derived from IVUS and OCT.
