Podcast
Questions and Answers
Which term is used to describe diffuse dysfunction attributed to multivessel coronary artery disease?
Which term is used to describe diffuse dysfunction attributed to multivessel coronary artery disease?
- Restrictive cardiomyopathy
- Dilated cardiomyopathy
- Hypertrophic cardiomyopathy
- Ischemic cardiomyopathy (correct)
What are cardiomyopathies characterized by?
What are cardiomyopathies characterized by?
- Morphologically and functionally normal myocardium
- Abnormal myocardium in the presence of other diseases
- Genetic disease (correct)
- Structural heart disease
What was the traditional classification of cardiomyopathies based on?
What was the traditional classification of cardiomyopathies based on?
- Echocardiographic findings
- Symptoms reported by patients
- Autopsy specimens (correct)
- Electrocardiographic findings
Which term is used to describe cardiomyopathy resulting from causes other than multivessel coronary artery disease?
Which term is used to describe cardiomyopathy resulting from causes other than multivessel coronary artery disease?
What term is sometimes applied to describe diffuse dysfunction attributed to multivessel coronary artery disease?
What term is sometimes applied to describe diffuse dysfunction attributed to multivessel coronary artery disease?
Which cardiomyopathy is now defined more on the basis of abnormal diastolic function?
Which cardiomyopathy is now defined more on the basis of abnormal diastolic function?
Why is the classification scheme based on phenotype considered increasingly inadequate?
Why is the classification scheme based on phenotype considered increasingly inadequate?
Which term primarily describes the resulting syndrome of fluid retention in cardiomyopathy?
Which term primarily describes the resulting syndrome of fluid retention in cardiomyopathy?
What may be absent despite severe fluid retention in younger patients with cardiomyopathy?
What may be absent despite severe fluid retention in younger patients with cardiomyopathy?
What is the primary presentation for fulminant myocarditis?
What is the primary presentation for fulminant myocarditis?
Which imaging modality is increasingly used to provide further information on myocardial tissue characterization?
Which imaging modality is increasingly used to provide further information on myocardial tissue characterization?
Which type of inheritance pattern is most commonly seen in familial cardiomyopathies?
Which type of inheritance pattern is most commonly seen in familial cardiomyopathies?
What kind of genetic mutations are the most common in cardiomyopathy?
What kind of genetic mutations are the most common in cardiomyopathy?
How do missense mutations affect the normal allele in cardiomyopathy?
How do missense mutations affect the normal allele in cardiomyopathy?
What is haploinsufficiency in the context of cardiomyopathy?
What is haploinsufficiency in the context of cardiomyopathy?
Which type of mutations may create a truncated or unstable protein in cardiomyopathy?
Which type of mutations may create a truncated or unstable protein in cardiomyopathy?
What characterizes genetic cardiomyopathy in terms of penetrance?
What characterizes genetic cardiomyopathy in terms of penetrance?
How does sex influence penetrance and clinical severity in most cardiomyopathies?
How does sex influence penetrance and clinical severity in most cardiomyopathies?
In which type of mutation is the lack of a stable protein the cause of cardiomyopathy?
In which type of mutation is the lack of a stable protein the cause of cardiomyopathy?
What is a possible consequence of antiviral drugs used to treat chronic HIV?
What is a possible consequence of antiviral drugs used to treat chronic HIV?
In which regions has hepatitis C been particularly associated with cardiomyopathy?
In which regions has hepatitis C been particularly associated with cardiomyopathy?
What factor can complicate the clinical picture related to cardiomyopathy when treating chronic HIV?
What factor can complicate the clinical picture related to cardiomyopathy when treating chronic HIV?
What effect can interferon therapy have on cardiac function?
What effect can interferon therapy have on cardiac function?
Which viruses have been specifically implicated in myocarditis, besides hepatitis viruses?
Which viruses have been specifically implicated in myocarditis, besides hepatitis viruses?
What is the dominant injury site of SARS-CoV-2, leading to severe complications?
What is the dominant injury site of SARS-CoV-2, leading to severe complications?
Which cytokine is mentioned as possibly depressing cardiac function transiently?
Which cytokine is mentioned as possibly depressing cardiac function transiently?
Which family of RNA viruses was first implicated in causing clinical myocarditis in humans?
Which family of RNA viruses was first implicated in causing clinical myocarditis in humans?
Which of the following DNA viruses is well recognized to cause myocarditis and is also common in the healthy population?
Which of the following DNA viruses is well recognized to cause myocarditis and is also common in the healthy population?
Which virus may affect the cardiovascular system through infection of vascular endothelial cells?
Which virus may affect the cardiovascular system through infection of vascular endothelial cells?
Which virus was associated with an incidence of dilated cardiomyopathy (DCM) of 1–2% before the advent of highly active antiretroviral therapy?
Which virus was associated with an incidence of dilated cardiomyopathy (DCM) of 1–2% before the advent of highly active antiretroviral therapy?
Which virus has been associated with a lower incidence of cardiac disease due to the advent of highly active antiretroviral therapy?
Which virus has been associated with a lower incidence of cardiac disease due to the advent of highly active antiretroviral therapy?
Which technique detects viral genomes in the majority of patients with dilated cardiomyopathy (DCM)?
Which technique detects viral genomes in the majority of patients with dilated cardiomyopathy (DCM)?
Which of the following viruses may contribute to chronic cardiomyopathy despite serologic evidence of exposure in many children and most adults?
Which of the following viruses may contribute to chronic cardiomyopathy despite serologic evidence of exposure in many children and most adults?
What is a common feature of Chagas' disease related to the conduction system abnormalities?
What is a common feature of Chagas' disease related to the conduction system abnormalities?
Why is xenodiagnosis rarely performed in Chagas' disease diagnosis?
Why is xenodiagnosis rarely performed in Chagas' disease diagnosis?
Which medication is commonly used to treat heart failure manifestations in advanced stages of Chagas' disease?
Which medication is commonly used to treat heart failure manifestations in advanced stages of Chagas' disease?
What is a known side effect of the antiparasitic therapies benznidazole and nifurtimox?
What is a known side effect of the antiparasitic therapies benznidazole and nifurtimox?
Why was the role of antiparasitic therapy left unclear in the trial with adults having Chagas' cardiomyopathy?
Why was the role of antiparasitic therapy left unclear in the trial with adults having Chagas' cardiomyopathy?
What makes the dilated ventricles in Chagas' disease particularly thrombogenic?
What makes the dilated ventricles in Chagas' disease particularly thrombogenic?
Why are two separate positive serologic tests needed to diagnose Chagas' disease?
Why are two separate positive serologic tests needed to diagnose Chagas' disease?
In Chagas' disease, what is a major focus of treatment in advanced stages?
In Chagas' disease, what is a major focus of treatment in advanced stages?
What is the main characteristic of the dilated ventricles in Chagas' disease related to thrombogenesis?
What is the main characteristic of the dilated ventricles in Chagas' disease related to thrombogenesis?
Which diagnostic method for Chagas' disease lacks sufficient specificity and sensitivity, requiring two positive tests for confirmation?
Which diagnostic method for Chagas' disease lacks sufficient specificity and sensitivity, requiring two positive tests for confirmation?